Brief Information of the Cell Line and Protein
Cell Line ID: CL000961 , H2.35
 Cell Line Info 
Category Transformed cell line
Organism
Mus musculus (Mouse)
Protein ID: PT06585 , Very long chain fatty acid elongase 6
 Protein Info 
Gene Name ELOVL6
Organism Mus musculus, Mouse
Protein Classification Enzyme
Uniprot ID Q920L5
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000961
 Cell Line Info 
 Protein ID: PT06585
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0202018
 Compound Info 
4-Fluoro-N-{[(+)-(4S)-2-oxo-6-(1H-pyrazol-5-yl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-4-yl]methyl}benzamide
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C20H14F4N4O3
  1
1
IC50 = 3.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0506517
 Compound Info 
4-Fluoro-N-{[(+)-2-oxo-6-(1H-pyrazol-4-yl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-4-yl]methyl}benzamide
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C20H14F4N4O3
  1
1
IC50 = 50 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0497072
 Compound Info 
4-Fluoro-N-{[(+)-2-oxo-6-(1H-pyrazol-1-yl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-4-yl]methyl}benzamide
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C20H14F4N4O3
  1
1
IC50 = 58 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0497071
 Compound Info 
N-[[6-chloro-2-oxo-4-(trifluoromethyl)-1H-3,1-benzoxazin-4-yl]methyl]-4-fluorobenzamide
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C17H11ClF4N2O3
  1
1
IC50 = 131 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0514616
 Compound Info 
1-{[(-)-6-Chloro-2-oxo-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-4-yl]methyl}-3-(4-fluorophenyl)urea
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C17H12ClF4N3O3
  1
1
IC50 = 377 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS