| Compound ID |
Compound Name |
Compound Formula |
|
CP0568675
|
4-[3-(3-fluoropyrazol-1-yl)cyclobutyl]-6-(3-pyrazol-1-ylcyclobutyl)oxypyrimidine
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|
C18H19FN6O
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0547090
|
CHEMBL5092963
Show/Hide
|
C21H23N5O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0496474
|
4-[3-(4-fluoropyrazol-1-yl)cyclobutyl]-6-(3-pyrazol-1-ylcyclobutyl)oxypyrimidine
Show/Hide
|
C18H19FN6O
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0574216
|
4-[3-(3-chloropyrazol-1-yl)cyclobutyl]-6-(3-pyrazol-1-ylcyclobutyl)oxypyrimidine
Show/Hide
|
C18H19ClN6O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0549528
|
4-[6-[2-(4-fluorophenyl)ethoxy]pyrimidin-4-yl]-1,4-oxazepane
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|
C17H20FN3O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0543583
|
(2S)-4-[6-[3-(1,3-oxazol-2-yl)cyclobutyl]oxypyrimidin-4-yl]-2-phenylmorpholine
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|
C21H22N4O3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0549529
|
4-[6-[3-(5-methylpyrazol-1-yl)propoxy]pyrimidin-4-yl]-2-phenylmorpholine
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|
C21H25N5O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0564591
|
4-[3-(5-methylpyrazol-1-yl)propoxy]-6-piperidin-1-ylpyrimidine
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|
C16H23N5O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0564592
|
4-[6-[3-(5-methylpyrazol-1-yl)propoxy]pyrimidin-4-yl]-2-(trifluoromethyl)morpholine
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|
C16H20F3N5O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0484288
|
(2S)-4-[6-[3-(1,3,4-oxadiazol-2-yl)cyclobutyl]oxypyrimidin-4-yl]-2-phenylmorpholine
Show/Hide
|
C20H21N5O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0579023
|
(2S)-2-phenyl-4-[6-[3-(triazol-1-yl)cyclobutyl]oxypyrimidin-4-yl]morpholine
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|
C20H22N6O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0573271
|
CHEMBL5084780
Show/Hide
|
C18H20N6O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0570415
|
4-[6-[2-(4-fluorophenyl)ethoxy]pyrimidin-4-yl]morpholine
Show/Hide
|
C16H18FN3O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0540391
|
1-(2-fluorophenyl)-N-[1-(2-fluoropyridin-4-yl)pyrazol-3-yl]cyclopropane-1-carboxamide
Show/Hide
|
C18H14F2N4O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0577249
|
(2S)-2-phenyl-4-[6-(3-phenylcyclobutyl)oxypyrimidin-4-yl]morpholine
Show/Hide
|
C24H25N3O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0496475
|
6-[2-(4-fluorophenyl)ethoxy]-N-methyl-N-(oxolan-3-yl)pyrimidin-4-amine
Show/Hide
|
C17H20FN3O2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0573272
|
6-[2-(4-fluorophenyl)ethoxy]-N,N-dimethylpyrimidin-4-amine
Show/Hide
|
C14H16FN3O
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0543584
|
4-[2-(4-fluorophenyl)ethoxy]-6-piperidin-1-ylpyrimidine
Show/Hide
|
C17H20FN3O
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0564593
|
8-[6-[3-(5-methylpyrazol-1-yl)propoxy]pyrimidin-4-yl]-2,5-dioxa-8-azaspiro[3.5]nonane
Show/Hide
|
C17H23N5O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0484289
|
4-[2-(5-methylpyrazol-1-yl)ethoxy]-6-piperidin-1-ylpyrimidine
Show/Hide
|
C15H21N5O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0484291
|
2-(2-methylpyrazol-3-yl)-4-[6-[3-(5-methylpyrazol-1-yl)propoxy]pyrimidin-4-yl]morpholine
Show/Hide
|
C19H25N7O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0579024
|
4-(3-pyrazol-1-ylcyclobutyl)-6-(3-pyrazol-1-ylcyclobutyl)oxypyrimidine
Show/Hide
|
C18H20N6O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0543585
|
1-[6-[2-(4-fluorophenyl)ethoxy]pyrimidin-4-yl]azepane
Show/Hide
|
C18H22FN3O
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0547089
|
6-[6-[3-(5-methylpyrazol-1-yl)propoxy]pyrimidin-4-yl]-3-oxa-6-azabicyclo[3.1.1]heptane
Show/Hide
|
C16H21N5O2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0564594
|
4-[2-(4-fluorophenyl)ethoxy]-6-pyrrolidin-1-ylpyrimidine
Show/Hide
|
C16H18FN3O
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0484292
|
2-[2-(4-fluorophenyl)ethoxy]-4-piperidin-1-ylpyridine
Show/Hide
|
C18H21FN2O
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0564595
|
2-[2-(4-fluorophenyl)ethoxy]-5-pyridin-3-ylpyridine
Show/Hide
|
C18H15FN2O
|
1
|
| 1 |
IC50 = 6700 nM
|
|
|
