Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT04427 , Free fatty acid receptor 4
Gene Name FFAR4
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q5NUL3
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT04427
 
Compound ID Compound Name Compound Formula
CP0219930
3-[(2R)-6-[3-fluoro-4-methoxy-6-(3-methoxycyclobutyl)oxypyridin-2-yl]-3,4-dihydro-2H-chromen-2-yl]propanoic acid
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C23H26FNO6
 2
1
EC50 = 5 nM
   TI
   LI
   LO
   TS
2
EC50 = 14 nM
   TI
   LI
   LO
   TS
CP0399970
3-[(2R)-6-[3-chloro-2-fluoro-5-[(5-methyl-1,3-thiazol-2-yl)oxy]phenyl]-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C22H19ClFNO4S
 2
1
EC50 = 5.6 nM
   TI
   LI
   LO
   TS
2
EC50 = 14 nM
   TI
   LI
   LO
   TS
CP0380760
3-[(2R)-6-(6-cyclobutyloxy-3-fluoro-4-methoxypyridin-2-yl)-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C22H24FNO5
 2
1
EC50 = 6.2 nM
   TI
   LI
   LO
   TS
2
EC50 = 15 nM
   TI
   LI
   LO
   TS
CP0414416
(1R,2R)-2-[(2R)-6-(6-cyclobutyloxy-3-fluoro-4-methoxypyridin-2-yl)-3,4-dihydro-2H-chromen-2-yl]cyclopropane-1-carboxylic acid
   Show/Hide
C23H24FNO5
 2
1
EC50 = 7.8 nM
   TI
   LI
   LO
   TS
2
EC50 = 18 nM
   TI
   LI
   LO
   TS
CP0447471
(1R,2R)-2-[(2R)-6-(5-cyclobutyloxy-2-fluoro-3-methoxyphenyl)-3,4-dihydro-2H-chromen-2-yl]cyclopropane-1-carboxylic acid
   Show/Hide
C24H25FO5
 2
1
EC50 = 8 nM
   TI
   LI
   LO
   TS
2
EC50 = 25 nM
   TI
   LI
   LO
   TS
CP0414856
3-[(2R)-6-(3-chloro-5-cyclobutyloxy-2-fluorophenyl)-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C22H22ClFO4
 2
1
EC50 = 8.3 nM
   TI
   LI
   LO
   TS
2
EC50 = 40 nM
   TI
   LI
   LO
   TS
CP0432167
3-[(2R)-6-(5-cyclobutyloxy-2-fluoro-3-methoxyphenyl)-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C23H25FO5
 2
1
EC50 = 9 nM
   TI
   LI
   LO
   TS
2
EC50 = 15 nM
   TI
   LI
   LO
   TS
CP0432202
3-[(2R)-6-(5-cyclobutyloxy-2-fluorophenyl)-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C22H23FO4
 2
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
2
EC50 = 28 nM
   TI
   LI
   LO
   TS
CP0466963
3-[(2R)-6-[2-fluoro-3-methoxy-5-(trifluoromethoxy)phenyl]-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C20H18F4O5
 2
1
EC50 = 11 nM
   TI
   LI
   LO
   TS
2
EC50 = 25 nM
   TI
   LI
   LO
   TS
CP0432201
3-[(2R)-6-(5-cyclobutyloxy-2,3-difluorophenyl)-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C22H22F2O4
 2
1
EC50 = 13 nM
   TI
   LI
   LO
   TS
2
EC50 = 21 nM
   TI
   LI
   LO
   TS
CP0432203
3-[(2R)-6-[2-fluoro-3-methoxy-5-[(5-methyl-1,3-thiazol-2-yl)oxy]phenyl]-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C23H22FNO5S
 2
1
EC50 = 13 nM
   TI
   LI
   LO
   TS
2
EC50 = 37 nM
   TI
   LI
   LO
   TS
CP0408970
3-[(2R)-6-[2-fluoro-5-(trifluoromethoxy)phenyl]-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C19H16F4O4
 2
1
EC50 = 17 nM
   TI
   LI
   LO
   TS
2
EC50 = 170 nM
   TI
   LI
   LO
   TS
CP0414422
3-[(2R)-6-[3-chloro-2-fluoro-5-(trifluoromethoxy)phenyl]-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C19H15ClF4O4
 2
1
EC50 = 17 nM
   TI
   LI
   LO
   TS
2
EC50 = 72 nM
   TI
   LI
   LO
   TS
CP0414423
(1R,2R)-2-[(2R)-6-[2,3-difluoro-5-(3-methoxycyclobutyl)oxyphenyl]-3,4-dihydro-2H-chromen-2-yl]cyclopropane-1-carboxylic acid
   Show/Hide
C24H24F2O5
 2
1
EC50 = 17 nM
   TI
   LI
   LO
   TS
2
EC50 = 45 nM
   TI
   LI
   LO
   TS
CP0048253
4-[2,6-difluoro-4-[2-fluoro-5-(trifluoromethoxy)phenyl]phenoxy]butanoic acid
   Show/Hide
C17H12F6O4
 1
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
CP0380758
3-[(2R)-6-(6-cyclobutyloxy-3-fluoropyridin-2-yl)-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C21H22FNO4
 2
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
2
EC50 = 30 nM
   TI
   LI
   LO
   TS
CP0048202
3-[(2R)-6-[3,4-difluoro-6-(3-methoxycyclobutyl)oxypyridin-2-yl]-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C22H23F2NO5
 2
1
EC50 = 24 nM
   TI
   LI
   LO
   TS
2
EC50 = 35 nM
   TI
   LI
   LO
   TS
CP0432166
5-[2-[(2R)-6-(5-cyclopropyloxy-2-fluoro-3-methoxyphenyl)-3,4-dihydro-2H-chromen-2-yl]ethyl]-2H-tetrazole
   Show/Hide
C22H23FN4O3
 2
1
EC50 = 32 nM
   TI
   LI
   LO
   TS
2
EC50 = 51 nM
   TI
   LI
   LO
   TS
CP0410368
(1R,2R)-2-[(2R)-6-[2-fluoro-5-(trifluoromethoxy)phenyl]-3,4-dihydro-2H-chromen-2-yl]cyclopropane-1-carboxylic acid
   Show/Hide
C20H16F4O4
 2
1
EC50 = 33 nM
   TI
   LI
   LO
   TS
2
EC50 = 69 nM
   TI
   LI
   LO
   TS
CP0380759
3-[(2S)-6-[2-fluoro-5-(trifluoromethoxy)phenyl]-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C19H16F4O4
 2
1
EC50 = 42 nM
   TI
   LI
   LO
   TS
2
EC50 = 180 nM
   TI
   LI
   LO
   TS
CP0432168
5-[2-[(2R)-6-[2-fluoro-3-methoxy-5-(3-methoxycyclobutyl)oxyphenyl]-3,4-dihydro-2H-chromen-2-yl]ethyl]-2H-tetrazole
   Show/Hide
C24H27FN4O4
 2
1
EC50 = 43 nM
   TI
   LI
   LO
   TS
2
EC50 = 53 nM
   TI
   LI
   LO
   TS
CP0432672
3-[3,5-difluoro-4-[[5-(trifluoromethyl)-3-[4-(trifluoromethyl)phenyl]-1,2-thiazol-4-yl]methoxy]phenyl]propanoic acid
   Show/Hide
C21H13F8NO3S
 1
1
EC50 = 51 nM
   TI
   LI
   LO
   TS
CP0447470
(1R,2R)-2-[(2R)-6-[2-fluoro-3-methoxy-5-(3-methoxycyclobutyl)oxyphenyl]-3,4-dihydro-2H-chromen-2-yl]cyclopropane-1-carboxylic acid
   Show/Hide
C25H27FO6
 2
1
EC50 = 55 nM
   TI
   LI
   LO
   TS
2
EC50 = 78 nM
   TI
   LI
   LO
   TS
CP0048254
4-[4-[2-chloro-5-(trifluoromethoxy)phenyl]phenoxy]butanoic acid
   Show/Hide
C17H14ClF3O4
 1
1
EC50 = 57 nM
   TI
   LI
   LO
   TS
CP0153988
4-[4-[2-fluoro-5-(3-fluorophenoxy)phenyl]phenoxy]butanoic acid
   Show/Hide
C22H18F2O4
 1
1
EC50 = 60 nM
   TI
   LI
   LO
   TS
CP0478382
3-[4-[[3-(4-ethylphenyl)-5-(trifluoromethyl)-1,2-oxazol-4-yl]methoxy]-3,5-difluorophenyl]propanoic acid
   Show/Hide
C22H18F5NO4
 1
1
EC50 = 60 nM
   TI
   LI
   LO
   TS
CP0432671
3-[4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-3,5-difluorophenyl]propanoic acid
   Show/Hide
C20H13ClF5NO3S
 1
1
EC50 = 62 nM
   TI
   LI
   LO
   TS
CP0048255
3-[5-[2-fluoro-5-(trifluoromethoxy)phenyl]-1-benzofuran-2-yl]propanoic acid
   Show/Hide
C18H12F4O4
 1
1
EC50 = 63 nM
   TI
   LI
   LO
   TS
CP0302776
4-[4-(5-cyclopropyloxy-2-fluorophenyl)phenoxy]butanoic acid
   Show/Hide
C19H19FO4
 1
1
EC50 = 66 nM
   TI
   LI
   LO
   TS
CP0172418
2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C19H23ClF3NO3
 2
1
EC50 = 66 nM
   TI
   LI
   LO
   TS
2
EC50 = 98 nM
   TI
   LI
   LO
   TS
CP0048251
3-[5-(3-cyclobutyloxy-5-methylphenyl)-1-benzofuran-2-yl]propanoic acid
   Show/Hide
C22H22O4
 1
1
EC50 = 68 nM
   TI
   LI
   LO
   TS
CP0550388
3-[3,5-difluoro-4-[[3-phenyl-5-(trifluoromethyl)-1,2-oxazol-4-yl]methoxy]phenyl]propanoic acid
   Show/Hide
C20H14F5NO4
 1
1
EC50 = 69 nM
   TI
   LI
   LO
   TS
CP0122626
3-[4-[[1-(4-chlorophenyl)-3-(trifluoromethyl)pyrrol-2-yl]methoxy]-3,5-difluorophenyl]propanoic acid
   Show/Hide
C21H15ClF5NO3
 1
1
EC50 = 69 nM
   TI
   LI
   LO
   TS
CP0411848
3-[4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-3,5-difluoro-2-methylphenyl]propanoic acid
   Show/Hide
C21H15ClF5NO3S
 1
1
EC50 = 71 nM
   TI
   LI
   LO
   TS
CP0451470
3-[(2R)-6-(5-cyclobutyloxy-2-fluoropyridin-3-yl)-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C21H22FNO4
 2
1
EC50 = 79 nM
   TI
   LI
   LO
   TS
2
EC50 = 140 nM
   TI
   LI
   LO
   TS
CP0370088
3-[5-[2-fluoro-5-(trifluoromethoxy)phenyl]-1-benzofuran-2-yl]-2-methylpropanoic acid
   Show/Hide
C19H14F4O4
 1
1
EC50 = 83 nM
   TI
   LI
   LO
   TS
CP0386426
3-[3-bromo-4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]phenyl]propanoic acid
   Show/Hide
C20H14BrClF3NO3S
 1
1
EC50 = 83 nM
   TI
   LI
   LO
   TS
CP0377505
5-[2-[(2R)-6-(5-cyclobutyloxy-2-fluorophenyl)-3,4-dihydro-2H-chromen-2-yl]ethyl]-2H-tetrazole
   Show/Hide
C22H23FN4O2
 2
1
EC50 = 84 nM
   TI
   LI
   LO
   TS
2
EC50 = 220 nM
   TI
   LI
   LO
   TS
CP0547884
3-[4-[[3-(4-chloro-3-fluorophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-3,5-difluorophenyl]propanoic acid
   Show/Hide
C20H12ClF6NO3S
 1
1
EC50 = 86 nM
   TI
   LI
   LO
   TS
CP0048249
4-[4-(2-chloro-5-pyridin-3-yloxyphenyl)phenoxy]butanoic acid
   Show/Hide
C21H18ClNO4
 1
1
EC50 = 88 nM
   TI
   LI
   LO
   TS
CP0561873
3-[3,5-difluoro-4-[[3-(4-methoxyphenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]phenyl]propanoic acid
   Show/Hide
C21H16F5NO4S
 1
1
EC50 = 91 nM
   TI
   LI
   LO
   TS
CP0085978
4-[4-[2-chloro-5-(trifluoromethoxy)phenyl]-2,6-dimethylphenoxy]butanoic acid
   Show/Hide
C19H18ClF3O4
 1
1
EC50 = 94 nM
   TI
   LI
   LO
   TS
CP0220860
3-[5-[5-(cyclopropanecarbonyl)-2-fluorophenyl]-1-benzofuran-2-yl]propanoic acid
   Show/Hide
C21H17FO4
 1
1
EC50 = 97 nM
   TI
   LI
   LO
   TS
CP0550433
3-[4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-2,3-difluorophenyl]propanoic acid
   Show/Hide
C20H13ClF5NO3S
 1
1
EC50 = 98 nM
   TI
   LI
   LO
   TS
CP0550436
3-[4-[[3-(4-ethylphenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-3,5-difluorophenyl]propanoic acid
   Show/Hide
C22H18F5NO3S
 1
1
EC50 = 98 nM
   TI
   LI
   LO
   TS
CP0432673
3-[3,5-difluoro-4-[[3-[4-(trifluoromethoxy)phenyl]-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]phenyl]propanoic acid
   Show/Hide
C21H13F8NO4S
 1
1
EC50 = 99 nM
   TI
   LI
   LO
   TS
CP0191029
4-[4-(2-fluoro-5-phenoxyphenyl)phenoxy]butanoic acid
   Show/Hide
C22H19FO4
 1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
CP0388566
3-[5-[2-chloro-5-(trifluoromethoxy)phenyl]-1-benzofuran-2-yl]propanoic acid
   Show/Hide
C18H12ClF3O4
 1
1
EC50 = 102 nM
   TI
   LI
   LO
   TS
CP0411847
3-[4-[[5-(4-chlorophenyl)-3-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C22H19ClF3NO3S
 1
1
EC50 = 105 nM
   TI
   LI
   LO
   TS
CP0495668
3-[4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-2,3,5-trifluorophenyl]propanoic acid
   Show/Hide
C20H12ClF6NO3S
 1
1
EC50 = 112 nM
   TI
   LI
   LO
   TS
CP0346517
4-[4-(2-chloro-5-ethoxyphenyl)phenoxy]butanoic acid
   Show/Hide
C18H19ClO4
 1
1
EC50 = 121 nM
   TI
   LI
   LO
   TS
CP0521809
3-[4-[[3-(4-chlorophenyl)-5-methyl-1,2-thiazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C22H22ClNO3S
 1
1
EC50 = 128 nM
   TI
   LI
   LO
   TS
CP0452049
(1S,2S)-2-[(2R)-6-[2-fluoro-5-(trifluoromethoxy)phenyl]-3,4-dihydro-2H-chromen-2-yl]cyclopropane-1-carboxylic acid
   Show/Hide
C20H16F4O4
 2
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
2
EC50 = 320 nM
   TI
   LI
   LO
   TS
CP0414419
5-[2-[(2R)-6-[2-fluoro-3-methoxy-5-(trifluoromethoxy)phenyl]-3,4-dihydro-2H-chromen-2-yl]ethyl]-2H-tetrazole
   Show/Hide
C20H18F4N4O3
 2
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
2
EC50 = 150 nM
   TI
   LI
   LO
   TS
CP0466653
2-[3-[2-fluoro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C19H23F4NO3
 2
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
2
EC50 = 700 nM
   TI
   LI
   LO
   TS
CP0561819
3-[4-[[3-(4-chlorophenyl)-5-propyl-1,2-oxazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C24H26ClNO4
 1
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
CP0550434
3-[3,5-difluoro-4-[[3-phenyl-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]phenyl]propanoic acid
   Show/Hide
C20H14F5NO3S
 1
1
EC50 = 132 nM
   TI
   LI
   LO
   TS
CP0530976
3-[4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-oxazol-4-yl]methoxy]-2,3-difluorophenyl]propanoic acid
   Show/Hide
C20H13ClF5NO4
 1
1
EC50 = 140 nM
   TI
   LI
   LO
   TS
CP0521077
3-[4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C22H19ClF3NO3S
 1
1
EC50 = 141 nM
   TI
   LI
   LO
   TS
CP0550435
3-[4-[[3-(4-chloro-2-fluorophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-3,5-difluorophenyl]propanoic acid
   Show/Hide
C20H12ClF6NO3S
 1
1
EC50 = 143 nM
   TI
   LI
   LO
   TS
CP0191030
4-[4-[2-fluoro-5-(trifluoromethoxy)phenyl]-2,6-dimethylphenoxy]butanoic acid
   Show/Hide
C19H18F4O4
 1
1
EC50 = 149 nM
   TI
   LI
   LO
   TS
CP0220861
3-[5-(3-cyclobutyloxyphenyl)-1-benzofuran-2-yl]propanoic acid
   Show/Hide
C21H20O4
 1
1
EC50 = 153 nM
   TI
   LI
   LO
   TS
CP0432675
3-[4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-3-ethylphenyl]propanoic acid
   Show/Hide
C22H19ClF3NO3S
 1
1
EC50 = 156 nM
   TI
   LI
   LO
   TS
CP0145583
3-[4-[[5-fluoro-2-(4-methylphenyl)phenyl]methoxy]phenyl]propanoic acid
   Show/Hide
C23H21FO3
 1
1
EC50 = 158.49 nM
   TI
   LI
   LO
   TS
CP0389905
3-[3,5-difluoro-4-[[3-(4-methylphenyl)-5-(trifluoromethyl)-1,2-oxazol-4-yl]methoxy]phenyl]-2-methylpropanoic acid
   Show/Hide
C22H18F5NO4
 1
1
EC50 = 160 nM
   TI
   LI
   LO
   TS
CP0446873
3-[4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-oxazol-4-yl]methoxy]-3,5-difluorophenyl]propanoic acid
   Show/Hide
C20H13ClF5NO4
 1
1
EC50 = 160 nM
   TI
   LI
   LO
   TS
CP0541480
3-[4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-oxazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C22H19ClF3NO4
 1
1
EC50 = 160 nM
   TI
   LI
   LO
   TS
CP0432669
3-[4-[[3-chloro-5-(4-ethylphenyl)-1,2-thiazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C23H24ClNO3S
 1
1
EC50 = 166 nM
   TI
   LI
   LO
   TS
CP0071468
4-[4-(3-phenoxyphenyl)phenoxy]butanoic acid
   Show/Hide
C22H20O4
 1
1
EC50 = 170 nM
   TI
   LI
   LO
   TS
CP0398696
5-[2-[(2R)-6-[2,3-difluoro-5-(3-methoxycyclobutyl)oxyphenyl]-3,4-dihydro-2H-chromen-2-yl]ethyl]-2H-tetrazole
   Show/Hide
C23H24F2N4O3
 2
1
EC50 = 170 nM
   TI
   LI
   LO
   TS
2
EC50 = 240 nM
   TI
   LI
   LO
   TS
CP0550387
3-[3,5-difluoro-4-[[3-(4-methylphenyl)-5-(trifluoromethyl)-1,2-oxazol-4-yl]methoxy]phenyl]propanoic acid
   Show/Hide
C21H16F5NO4
 1
1
EC50 = 180 nM
   TI
   LI
   LO
   TS
CP0294302
4-[4-[3-(4-methylphenoxy)phenyl]phenoxy]butanoic acid
   Show/Hide
C23H22O4
 1
1
EC50 = 182 nM
   TI
   LI
   LO
   TS
CP0386428
3-[4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-2,3,5,6-tetrafluorophenyl]propanoic acid
   Show/Hide
C20H11ClF7NO3S
 1
1
EC50 = 183 nM
   TI
   LI
   LO
   TS
CP0346511
4-[4-[2-chloro-5-(trifluoromethoxy)phenyl]-2-methylphenoxy]butanoic acid
   Show/Hide
C18H16ClF3O4
 1
1
EC50 = 185 nM
   TI
   LI
   LO
   TS
CP0562935
4-[4-[2-chloro-5-(trifluoromethoxy)phenyl]-3-fluorophenoxy]butanoic acid
   Show/Hide
C17H13ClF4O4
 1
1
EC50 = 186 nM
   TI
   LI
   LO
   TS
CP0048252
3-[5-(3-chloro-5-cyclobutyloxyphenyl)-1-benzofuran-2-yl]propanoic acid
   Show/Hide
C21H19ClO4
 1
1
EC50 = 188 nM
   TI
   LI
   LO
   TS
CP0396176
2-[3-(3,5-dichlorophenyl)-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C18H23Cl2NO2
 2
1
EC50 = 190 nM
   TI
   LI
   LO
   TS
2
EC50 = 220 nM
   TI
   LI
   LO
   TS
CP0519984
3-[3,5-difluoro-4-[[5-(trifluoromethyl)-3-[4-(trifluoromethyl)phenyl]-1,2-oxazol-4-yl]methoxy]phenyl]propanoic acid
   Show/Hide
C21H13F8NO4
 1
1
EC50 = 190 nM
   TI
   LI
   LO
   TS
CP0504415
4-[4-[2-chloro-5-(3-fluorophenoxy)phenyl]phenoxy]butanoic acid
   Show/Hide
C22H18ClFO4
 1
1
EC50 = 198 nM
   TI
   LI
   LO
   TS
CP0464376
2-[3-[2-cyano-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C20H23F3N2O3
 2
1
EC50 = 200 nM
   TI
   LI
   LO
   TS
2
EC50 = 370 nM
   TI
   LI
   LO
   TS
CP0190800
4-[4-[2-chloro-5-(1,3-thiazol-3-ium-3-yl)phenyl]phenoxy]butanoic acid
   Show/Hide
C19H17ClNO3S+
 1
1
EC50 = 204 nM
   TI
   LI
   LO
   TS
CP0495670
3-[4-[[3-(4-ethylphenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C24H24F3NO3S
 1
1
EC50 = 210 nM
   TI
   LI
   LO
   TS
CP0414409
3-[(2R)-6-(2-cyclobutyloxy-5-fluoropyridin-4-yl)-3,4-dihydro-2H-chromen-2-yl]propanoic acid
   Show/Hide
C21H22FNO4
 2
1
EC50 = 230 nM
   TI
   LI
   LO
   TS
2
EC50 = 250 nM
   TI
   LI
   LO
   TS
CP0561818
3-[3,5-difluoro-4-[[3-(4-fluorophenyl)-5-(trifluoromethyl)-1,2-oxazol-4-yl]methoxy]phenyl]propanoic acid
   Show/Hide
C20H13F6NO4
 1
1
EC50 = 230 nM
   TI
   LI
   LO
   TS
CP0153986
4-[4-[2-chloro-5-(trifluoromethoxy)phenyl]-3-methylphenoxy]butanoic acid
   Show/Hide
C18H16ClF3O4
 1
1
EC50 = 254 nM
   TI
   LI
   LO
   TS
CP0190955
4-[4-(5-ethoxy-2-fluorophenyl)phenoxy]butanoic acid
   Show/Hide
C18H19FO4
 1
1
EC50 = 290 nM
   TI
   LI
   LO
   TS
CP0478381
3-[4-[[3-(2-chloro-4-fluorophenyl)-5-(trifluoromethyl)-1,2-oxazol-4-yl]methoxy]-3,5-difluorophenyl]propanoic acid
   Show/Hide
C20H12ClF6NO4
 1
1
EC50 = 290 nM
   TI
   LI
   LO
   TS
CP0370086
4-[4-[2-fluoro-5-(trifluoromethoxy)phenyl]-2-methylphenoxy]butanoic acid
   Show/Hide
C18H16F4O4
 1
1
EC50 = 308 nM
   TI
   LI
   LO
   TS
CP0508098
5-[2-[(2R)-6-[2-fluoro-5-(trifluoromethoxy)phenyl]-3,4-dihydro-2H-chromen-2-yl]ethyl]-2H-tetrazole
   Show/Hide
C19H16F4N4O2
 2
1
EC50 = 330 nM
   TI
   LI
   LO
   TS
2
EC50 = 890 nM
   TI
   LI
   LO
   TS
CP0500287
2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]ethanol
   Show/Hide
C19H25ClF3NO2
 2
1
EC50 = 330 nM
   TI
   LI
   LO
   TS
2
EC50 = 4300 nM
   TI
   LI
   LO
   TS
CP0521076
3-[4-[[3-(4-cyanophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-3,5-difluorophenyl]propanoic acid
   Show/Hide
C21H13F5N2O3S
 1
1
EC50 = 332 nM
   TI
   LI
   LO
   TS
CP0464379
2-[3-[3-cyano-5-(trifluoromethylsulfanyl)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C20H23F3N2O2S
 2
1
EC50 = 360 nM
   TI
   LI
   LO
   TS
2
EC50 = 480 nM
   TI
   LI
   LO
   TS
CP0389908
3-[4-[[3-(4-chlorophenyl)-5-ethyl-1,2-oxazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C23H24ClNO4
 1
1
EC50 = 400 nM
   TI
   LI
   LO
   TS
CP0461738
2-[3-(3-chloro-2,5-difluorophenyl)-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C18H22ClF2NO2
 2
1
EC50 = 420 nM
   TI
   LI
   LO
   TS
2
EC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0432670
3-[4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)-1,2-thiazol-4-yl]methoxy]-2-(trifluoromethyl)phenyl]propanoic acid
   Show/Hide
C21H14ClF6NO3S
 1
1
EC50 = 421 nM
   TI
   LI
   LO
   TS
CP0503953
2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-11-methyl-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C20H25ClF3NO3
 2
1
EC50 = 440 nM
   TI
   LI
   LO
   TS
2
EC50 = 580 nM
   TI
   LI
   LO
   TS
CP0408977
4-[4-(1,2-benzoxazol-3-yl)-2,3-dichlorophenoxy]butanoic acid
   Show/Hide
C17H13Cl2NO4
 1
1
EC50 = 474 nM
   TI
   LI
   LO
   TS
CP0089979
4-[4-[3-(3-methoxyphenoxy)phenyl]phenoxy]butanoic acid
   Show/Hide
C23H22O5
 1
1
EC50 = 498 nM
   TI
   LI
   LO
   TS
CP0370087
3-[5-[3-(trifluoromethoxy)phenyl]-1-benzofuran-2-yl]propanoic acid
   Show/Hide
C18H13F3O4
 1
1
EC50 = 544 nM
   TI
   LI
   LO
   TS
CP0398697
4-[4-(2-phenoxyphenyl)phenoxy]butanoic acid
   Show/Hide
C22H20O4
 1
1
EC50 = 546 nM
   TI
   LI
   LO
   TS
CP0541899
3-[4-[[4-(4-ethylphenyl)thiophen-3-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C24H26O3S
 1
1
EC50 = 711 nM
   TI
   LI
   LO
   TS
CP0558473
3-[4-[[1-(4-ethylphenyl)pyrrol-2-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C24H27NO3
 1
1
EC50 = 750 nM
   TI
   LI
   LO
   TS
CP0478379
3-[4-[[3-(4-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C22H22ClNO4
 1
1
EC50 = 760 nM
   TI
   LI
   LO
   TS
CP0541897
3-[4-[[5-(4-chlorophenyl)-3-methyl-1,2-oxazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C22H22ClNO4
 1
1
EC50 = 810 nM
   TI
   LI
   LO
   TS
CP0534630
3-[5-[2-fluoro-5-(trifluoromethoxy)phenyl]-1-benzofuran-2-yl]butanoic acid
   Show/Hide
C19H14F4O4
 1
1
EC50 = 819 nM
   TI
   LI
   LO
   TS
CP0558475
3-[4-[[3-(4-ethylphenyl)thiophen-2-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C24H26O3S
 1
1
EC50 = 900 nM
   TI
   LI
   LO
   TS
CP0389787
3-[4-[[1-(4-chlorophenyl)pyrrol-2-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C22H22ClNO3
 1
1
EC50 = 930 nM
   TI
   LI
   LO
   TS
CP0534629
4-[4-[2-fluoro-5-(trifluoromethoxy)phenyl]phenoxy]butanoic acid
   Show/Hide
C17H14F4O4
 1
1
EC50 = 946 nM
   TI
   LI
   LO
   TS
CP0464377
3-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]propanoic acid
   Show/Hide
C20H25ClF3NO3
 2
1
EC50 = 1000 nM
   TI
   LI
   LO
   TS
2
EC50 = 2700 nM
   TI
   LI
   LO
   TS
CP0410580
3-[4-[[3-(4-chlorophenyl)-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C24H24ClNO4
 1
1
EC50 = 1090 nM
   TI
   LI
   LO
   TS
CP0478380
3-[4-[[2-(4-ethylphenyl)pyrazol-3-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C23H26N2O3
 1
1
EC50 = 1150 nM
   TI
   LI
   LO
   TS
CP0396175
2-[3-[2-fluoro-5-(trifluoromethyl)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C19H23F4NO2
 2
1
EC50 = 1200 nM
   TI
   LI
   LO
   TS
2
EC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0546707
3-[4-[[3-(4-chlorophenyl)-1,2-thiazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C21H20ClNO3S
 1
1
EC50 = 1342 nM
   TI
   LI
   LO
   TS
CP0176090
3-[4-[[5-fluoro-2-(4-methylphenyl)phenoxy]methyl]phenyl]propanoic acid
   Show/Hide
C23H21FO3
 1
1
EC50 = 1548.82 nM
   TI
   LI
   LO
   TS
CP0389785
3-[4-[[2-(4-chlorophenyl)pyrazol-3-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C21H21ClN2O3
 1
1
EC50 = 2030 nM
   TI
   LI
   LO
   TS
CP0442319
2-[9-[2-chloro-5-(trifluoromethoxy)phenyl]-1-oxa-9-azaspiro[5.5]undecan-3-yl]acetic acid
   Show/Hide
C18H21ClF3NO4
 2
1
EC50 = 2100 nM
   TI
   LI
   LO
   TS
2
EC50 = 5700 nM
   TI
   LI
   LO
   TS
CP0503952
2-[3-(2-chloro-5-methoxyphenyl)-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C19H26ClNO3
 2
1
EC50 = 2100 nM
   TI
   LI
   LO
   TS
2
EC50 = 2500 nM
   TI
   LI
   LO
   TS
CP0444001
N-[4-amino-3-(trifluoromethyl)phenyl]-4-methylbenzenesulfonamide
   Show/Hide
C14H13F3N2O2S
 1
1
EC50 = 2187.76 nM
   TI
   LI
   LO
   TS
CP0468351
9-[2-chloro-5-(trifluoromethoxy)phenyl]-9-azadispiro[2.2.56.23]tridecane-2-carboxylic acid
   Show/Hide
C20H23ClF3NO3
 2
1
EC50 = 2200 nM
   TI
   LI
   LO
   TS
2
EC50 = 3900 nM
   TI
   LI
   LO
   TS
CP0396172
2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-10-methyl-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C20H25ClF3NO3
 2
1
EC50 = 2700 nM
   TI
   LI
   LO
   TS
2
EC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0390098
3-[4-[[3-(4-chlorophenyl)-1,2-oxazol-4-yl]methoxy]-2,3-dimethylphenyl]propanoic acid
   Show/Hide
C21H20ClNO4
 1
1
EC50 = 2760 nM
   TI
   LI
   LO
   TS
CP0089978
4-[4-[2-(trifluoromethoxy)phenyl]phenoxy]butanoic acid
   Show/Hide
C17H15F3O4
 1
1
EC50 = 2999 nM
   TI
   LI
   LO
   TS
CP0516513
2-[3-(5-chloro-2,2-dimethyl-3H-1-benzofuran-7-yl)-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C22H30ClNO3
 2
1
EC50 = 3100 nM
   TI
   LI
   LO
   TS
2
EC50 = 3300 nM
   TI
   LI
   LO
   TS
CP0500271
2-[3-[4-(trifluoromethyl)pyridin-2-yl]-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C18H23F3N2O2
 2
1
EC50 = 3100 nM
   TI
   LI
   LO
   TS
2
EC50 = 9200 nM
   TI
   LI
   LO
   TS
CP0523670
2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]propanoic acid
   Show/Hide
C20H25ClF3NO3
 2
1
EC50 = 3500 nM
   TI
   LI
   LO
   TS
2
EC50 = 4400 nM
   TI
   LI
   LO
   TS
CP0421629
N-[4-amino-3-(trifluoromethyl)phenyl]-4-methoxybenzenesulfonamide
   Show/Hide
C14H13F3N2O3S
 1
1
EC50 = 3548.13 nM
   TI
   LI
   LO
   TS
CP0444000
N-[4-amino-3-(trifluoromethyl)phenyl]-4-ethylbenzenesulfonamide
   Show/Hide
C15H15F3N2O2S
 1
1
EC50 = 3981.07 nM
   TI
   LI
   LO
   TS
CP0444003
N-[4-amino-3-(trifluoromethyl)phenyl]-4-chlorobenzenesulfonamide
   Show/Hide
C13H10ClF3N2O2S
 1
1
EC50 = 4897.79 nM
   TI
   LI
   LO
   TS
CP0421627
N-[4-amino-3-(trifluoromethyl)phenyl]-4-bromobenzenesulfonamide
   Show/Hide
C13H10BrF3N2O2S
 1
1
EC50 = 5128.61 nM
   TI
   LI
   LO
   TS
CP0548697
3-[4-[(5-fluoro-2-methylphenoxy)methyl]phenyl]propanoic acid
   Show/Hide
C17H17FO3
 1
1
EC50 = 5248.07 nM
   TI
   LI
   LO
   TS
CP0555346
3-[4-[(2-bromo-5-fluorophenoxy)methyl]phenyl]propanoic acid
   Show/Hide
C16H14BrFO3
 1
1
EC50 = 5754.4 nM
   TI
   LI
   LO
   TS
CP0555347
3-[4-[(2-cyano-5-fluorophenoxy)methyl]phenyl]propanoic acid
   Show/Hide
C17H14FNO3
 1
1
EC50 = 6025.6 nM
   TI
   LI
   LO
   TS
CP0455040
4-[4-[2-(trifluoromethyl)phenyl]phenoxy]butanoic acid
   Show/Hide
C17H15F3O3
 1
1
EC50 = 8174 nM
   TI
   LI
   LO
   TS
CP0528378
N-[4-amino-3-(trifluoromethyl)phenyl]benzenesulfonamide
   Show/Hide
C13H11F3N2O2S
 1
1
EC50 = 8709.64 nM
   TI
   LI
   LO
   TS
CP0560520
N-[4-amino-3-(trifluoromethyl)phenyl]-4-fluorobenzenesulfonamide
   Show/Hide
C13H10F4N2O2S
 1
1
EC50 = 8912.51 nM
   TI
   LI
   LO
   TS
CP0421631
3-[4-[(5-fluoro-2-methoxyphenoxy)methyl]phenyl]propanoic acid
   Show/Hide
C17H17FO4
 1
1
EC50 = 9549.93 nM
   TI
   LI
   LO
   TS
CP0421625
3-[4-[(5-fluoro-2-methoxycarbonylphenoxy)methyl]phenyl]propanoic acid
   Show/Hide
C18H17FO5
 1
1
EC50 = 9772.37 nM
   TI
   LI
   LO
   TS
CP0464378
2-[3-[2-fluoro-5-(trifluoromethoxy)phenyl]-3,9-diazaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C18H22F4N2O3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0469180
2-[3-(2-chlorophenyl)-3-azaspiro[5.5]undecan-9-yl]acetic acid
   Show/Hide
C18H24ClNO2
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0421624
N-[4-amino-3-(trifluoromethyl)phenyl]-4-nitrobenzenesulfonamide
   Show/Hide
C13H10F3N3O4S
 1
1
EC50 = 12882.5 nM
   TI
   LI
   LO
   TS
CP0546071
N-(4-amino-3-nitrophenyl)benzenesulfonamide
   Show/Hide
C12H11N3O4S
 1
1
EC50 = 17782.79 nM
   TI
   LI
   LO
   TS
CP0018150
4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfonamide
   Show/Hide
C14H12F3NO2S
 1
1
EC50 = 29512.09 nM
   TI
   LI
   LO
   TS
CP0516866
N-[4-amino-3-(trifluoromethyl)phenyl]-4-(trifluoromethoxy)benzenesulfonamide
   Show/Hide
C14H10F6N2O3S
 1
1
EC50 = 30902.95 nM
   TI
   LI
   LO
   TS
CP0516865
N-[4-amino-3-(trifluoromethyl)phenyl]-4-tert-butylbenzenesulfonamide
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C17H19F3N2O2S
 1
1
EC50 = 39810.72 nM
   TI
   LI
   LO
   TS
CP0560519
N-[4-amino-3-(trifluoromethyl)phenyl]-4-hydroxybenzenesulfonamide
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C13H11F3N2O3S
 1
1
EC50 = 50118.72 nM
   TI
   LI
   LO
   TS
CP0562782
N-(4-amino-3-fluorophenyl)benzenesulfonamide
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C12H11FN2O2S
 1
1
EC50 = 63095.73 nM
   TI
   LI
   LO
   TS
CP0048250
4-[4-(3-phenylmethoxyphenyl)phenoxy]butanoic acid
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C23H22O4
 1
1
EC50 > 9950 nM
   TI
   LI
   LO
   TS
CP0508078
5-[2-[5-[2-fluoro-5-(trifluoromethoxy)phenyl]-1-benzofuran-2-yl]ethyl]-2H-tetrazole
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C18H12F4N4O2
 1
1
EC50 > 9950 nM
   TI
   LI
   LO
   TS
CP0541540
5-[2-fluoro-5-(trifluoromethoxy)phenyl]-1-benzofuran-2-carboxylic acid
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C16H8F4O4
 1
1
EC50 > 9950 nM
   TI
   LI
   LO
   TS
CP0271129
N-(4-aminophenyl)benzenesulfonamide
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C12H12N2O2S
 1
1
EC50 < 100000 nM
   TI
   LI
   LO
   TS
CP0421626
2-[[4-(2-carboxyethyl)phenyl]methoxy]-4-fluorobenzoic acid
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C17H15FO5
 1
1
EC50 < 100000 nM
   TI
   LI
   LO
   TS
CP0450881
N-(4-amino-3-methylphenyl)benzenesulfonamide
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C13H14N2O2S
 1
1
EC50 < 100000 nM
   TI
   LI
   LO
   TS
CP0516867
N-[4-amino-3-(trifluoromethyl)phenyl]-4-phenylbenzenesulfonamide
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C19H15F3N2O2S
 1
1
EC50 < 100000 nM
   TI
   LI
   LO
   TS