Brief Information of the Compound and Protein
Compound Name
(1R,2R)-2-[(2R)-6-(5-cyclobutyloxy-2-fluoro-3-methoxyphenyl)-3,4-dihydro-2H-chromen-2-yl]cyclopropane-1-carboxylic acid
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PubChem ID
CID: 134153298
Canonical SMILES
COc1cc(OC2CCC2)cc(c1F)-c1ccc2O[C@H](CCc2c1)[C@@H]1C[C@H]1C(O)=O
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Compound Formula C24H25FO5
Compound Structure
Protein Name
Free fatty acid receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
Q5NUL3
Gene Name
FFAR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 8 nM
   TI
   LI
   LO
   TS
2
EC50 = 25 nM
   TI
   LI
   LO
   TS