| Compound ID |
Compound Name |
Compound Formula |
|
CP0410640
|
1-(6-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)-3-methyl-pyrrole-2,5-dione
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|
C18H14N4O3S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0051980
|
1-(5-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)-3-methyl-pyrrole-2,5-dione
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|
C18H14N4O3S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0498669
|
2-Chloro-4-methyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
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|
C14H8ClF6N3O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0003541
|
4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino)-2-thiophen-2-yl-pyrimidine-5-carboxylic acid ethyl ester
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|
C16H14N4O4S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0384511
|
ethyl 4-ethyl-2-[methyl-(3-methyl-2,5-dioxopyrrol-1-yl)amino]pyrimidine-5-carboxylate
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|
C15H18N4O4
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0384510
|
ethyl 2-[(3-methyl-2,5-dioxopyrrol-1-yl)amino]-4-(5-methylthiophen-2-yl)pyrimidine-5-carboxylate
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|
C17H16N4O4S
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0383316
|
2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
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|
C14H5ClF9N3O
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0550900
|
1-[[5-benzoyl-4-(trifluoromethyl)pyrimidin-2-yl]amino]-3-methylpyrrole-2,5-dione
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|
C17H11F3N4O3
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0376529
|
2-Fluoro-4-trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
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|
C14H5F10N3O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0005108
|
4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino)-2-phenyl-pyrimidine-5-carboxylic acid ethyl ester
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|
C18H16N4O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0415493
|
2-chloro-8-(trifluoromethyl)-6H-pyrimido[4,5-b][1,5]benzothiazepin-5-one
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|
C12H5ClF3N3OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0492354
|
2,4-Dichloro-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
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|
C13H5Cl2F6N3O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0536665
|
tert-butyl 2-[(3-methyl-2,5-dioxopyrrol-1-yl)amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate
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|
C15H15F3N4O4
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0404840
|
2-Chloro-4-ethyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
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|
C15H10ClF6N3O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0459902
|
2-Chloro-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
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|
C13H6ClF6N3O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0498668
|
ethyl 2-[methyl-(3-methyl-2,5-dioxopyrrol-1-yl)amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate
Show/Hide
|
C14H13F3N4O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0480521
|
2-Chloro-4-phenyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
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|
C19H10ClF6N3O
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0542165
|
ethyl 4-ethyl-2-[(3-methyl-2,5-dioxopyrrol-1-yl)amino]pyrimidine-5-carboxylate
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|
C14H16N4O4
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0384144
|
2-Chloro-4-propyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
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|
C16H12ClF6N3O
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0384514
|
2-chloro-N-(3,5-dichlorophenyl)-4-methylpyrimidine-5-carboxamide
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|
C12H8Cl3N3O
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0514540
|
2-Chloro-4-pentafluoroethyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
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|
C15H5ClF11N3O
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0572712
|
3-methyl-1-[[5-(2-methyl-1,3-oxazol-4-yl)-4-thiophen-2-ylpyrimidin-2-yl]amino]pyrrole-2,5-dione
Show/Hide
|
C17H13N5O3S
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0550899
|
1-[[4-ethyl-5-(2-methyl-1,3-oxazol-4-yl)pyrimidin-2-yl]amino]-3-methylpyrrole-2,5-dione
Show/Hide
|
C15H15N5O3
|
1
|
| 1 |
IC50 = 830 nM
|
|
|
|
CP0003569
|
4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino)-2-trifluoromethyl-pyrimidine-5-carboxylic acid ethyl ester
Show/Hide
|
C13H11F3N4O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0405526
|
6-Chloro-pyridazine-3-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C13H6ClF6N3O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0400323
|
2-chloro-8-(trifluoromethyl)-6H-pyrimido[4,5-b][1,5]benzoxazepin-5-one
Show/Hide
|
C12H5ClF3N3O2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0384512
|
ethyl 2-[(3-methyl-2,5-dioxopyrrol-1-yl)amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate
Show/Hide
|
C13H11F3N4O4
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0400324
|
5-Chloro-pyrazine-2-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C13H6ClF6N3O
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0498667
|
1-[[5-acetyl-4-(trifluoromethyl)pyrimidin-2-yl]amino]-3-methylpyrrole-2,5-dione
Show/Hide
|
C12H9F3N4O3
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0542543
|
2-chloro-8-(trifluoromethyl)-6H-pyrimido[5,4-c]quinolin-5-one
Show/Hide
|
C12H5ClF3N3O
|
1
|
| 1 |
IC50 = 6100 nM
|
|
|
|
CP0506601
|
2-Chloro-4-thiophen-2-yl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C17H8ClF6N3OS
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0572713
|
2-chloro-8-(trifluoromethyl)-6,11-dihydropyrimido[5,4-c][1]benzazepin-5-one
Show/Hide
|
C13H7ClF3N3O
|
1
|
| 1 |
IC50 = 8500 nM
|
|
|
|
CP0536628
|
6-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-chloropyrrolo[3,4-d]pyrimidine-5,7-dione
Show/Hide
|
C15H6ClF6N3O2
|
1
|
| 1 |
IC50 = 9400 nM
|
|
|
|
CP0550902
|
6-[3,5-bis(trifluoromethyl)phenyl]-2-chloropyrrolo[3,4-d]pyrimidine-5,7-dione
Show/Hide
|
C14H4ClF6N3O2
|
1
|
| 1 |
IC50 = 9400 nM
|
|
|
|
CP0384513
|
2,4-Bis-trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C15H5F12N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0392344
|
2-Phenyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C19H11F6N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0400325
|
6-Chloro-4-trifluoromethyl-pyridazine-3-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C14H5ClF9N3O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0400788
|
2-Cyano-4-trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C15H5F9N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0430866
|
2-Chloro-6-methyl-pyrimidine-4-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C14H8ClF6N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0480399
|
2-Trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C14H6F9N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0483389
|
2-Methyl-4-trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C15H8F9N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0504199
|
4-Chloro-2-trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C14H5ClF9N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0514553
|
2,6-Dichloro-pyrimidine-4-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C13H5Cl2F6N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0516103
|
2-Chloro-6-trifluoromethyl-pyrimidine-4-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C14H5ClF9N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0565411
|
4-Methyl-2-trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide
Show/Hide
|
C15H8F9N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0400787
|
N-[2,4-bis(trifluoromethyl)phenyl]-2-chloro-6-methylpyrimidine-4-carboxamide
Show/Hide
|
C14H8ClF6N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0523088
|
[2-chloro-4-(trifluoromethyl)pyrimidin-5-yl]-[7-(trifluoromethyl)-2,4-dihydro-3,1-benzoxazin-1-yl]methanone
Show/Hide
|
C15H8ClF6N3O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0551429
|
2-chloro-8-(trifluoromethyl)-6,11-dihydropyrimido[5,4-c][1,5]benzodiazepin-5-one
Show/Hide
|
C12H6ClF3N4O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0551430
|
N-[2,4-bis(trifluoromethyl)phenyl]-2-chloro-6-(trifluoromethyl)pyrimidine-4-carboxamide
Show/Hide
|
C14H5ClF9N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0422718
|
N-[3,5-bis(trifluoromethyl)phenyl]-4-chloro-2-(trifluoromethyl)benzamide
Show/Hide
|
C16H7ClF9NO
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
