Brief Information of the Cell Line and Protein
Cell Line ID: CL000004 , SH-SY5Y
Synonyms
SH-Sy5y
SHSY5Y
SHSY-5Y
SK-SH-SY5Y
SY5Y
SH-SY5Y Parental
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0019
Protein ID: PT04172 , Thioredoxin reductase 1, cytoplasmic
Gene Name TXNRD1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q16881
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000004  Protein ID: PT04172
 
Compound ID Compound Name Compound Formula
CP0096608
2-[[2-(tert-butylamino)-1-(4-fluorophenyl)-2-oxoethyl]-methylamino]ethyl (E)-4-(4-fluorophenyl)-4-oxobut-2-enoate
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C25H28F2N2O4
 1
1
IC50 = 7260 nM
   TI
   LI
   LO
   TS
CP0060423
(E)-N-[2-(tert-butylamino)-2-oxo-1-(3,4,5-trimethoxyphenyl)ethyl]-4-(4-fluorophenyl)-N-(3-methylbutyl)-4-oxobut-2-enamide
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C30H39FN2O6
 1
1
IC50 = 8580 nM
   TI
   LI
   LO
   TS
CP0563588
(E)-N-[2-(tert-butylamino)-1-(4-methoxyphenyl)-2-oxoethyl]-4-(4-methylphenyl)-4-oxo-N-propan-2-ylbut-2-enamide
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C27H34N2O4
 1
1
IC50 = 16010 nM
   TI
   LI
   LO
   TS
CP0358695
(E)-N-[2-(tert-butylamino)-1-(4-fluorophenyl)-2-oxoethyl]-N-cyclopropyl-4-(4-fluorophenyl)-4-oxobut-2-enamide
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C25H26F2N2O3
 1
1
IC50 = 17440 nM
   TI
   LI
   LO
   TS
CP0266776
(E)-N-[2-(cyclohexylamino)-1-(4-fluorophenyl)-2-oxoethyl]-N-cyclopropyl-4-(4-methylphenyl)-4-oxobut-2-enamide
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C28H31FN2O3
 1
1
IC50 = 29300 nM
   TI
   LI
   LO
   TS
CP0363278
N-benzyl-2-[butyl-[(E)-4-(4-fluorophenyl)-4-oxobut-2-enoyl]amino]-3,3-dimethylbutanamide
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C27H33FN2O3
 1
1
IC50 = 30540 nM
   TI
   LI
   LO
   TS
CP0176626
(E)-N-[2-(benzylamino)-1-(5-methylpyrimidin-2-yl)-2-oxoethyl]-N-cyclopropyl-4-(4-methylphenyl)-4-oxobut-2-enamide
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C28H28N4O3
 1
1
IC50 = 31840 nM
   TI
   LI
   LO
   TS
CP0040187
CHEBI:8241
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C17H19NO5
 1
1
IC50 = 45880 nM
   TI
   LI
   LO
   TS
CP0096609
(E)-N-cyclohexyl-N-[2-(cyclohexylamino)-1-(2-methoxyphenyl)-2-oxoethyl]-4-(4-methylphenyl)-4-oxobut-2-enamide
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C32H40N2O4
 1
1
IC50 = 51240 nM
   TI
   LI
   LO
   TS
CP0369467
(E)-N-[2-(tert-butylamino)-1-(3,4-dimethoxyphenyl)-2-oxoethyl]-N-cyclopropyl-4-(4-methylphenyl)-4-oxobut-2-enamide
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C28H34N2O5
 1
1
IC50 = 76620 nM
   TI
   LI
   LO
   TS
CP0266777
(E)-N-[2-(cyclohexylamino)-1-(4-methylphenyl)-2-oxoethyl]-4-(4-methylphenyl)-4-oxo-N-propylbut-2-enamide
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C29H36N2O3
 1
1
IC50 = 81630 nM
   TI
   LI
   LO
   TS