Brief Information of the Cell Line and Protein
Cell Line ID: CL000184 , RK3E
Category Transformed cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0503
Protein ID: PT04149 , Retinoic acid receptor RXR-alpha
Gene Name RXRA
Organism Rattus norvegicus, Rat
Protein Classification Transcription factor
Uniprot ID Q05343
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000184  Protein ID: PT04149
 
Compound ID Compound Name Compound Formula
CP0004259
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid
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C24H28O2
 1
1
EC50 = 40 nM
   TI
   LI
   LO
   TS
CP0076500
(2E,4E,6Z,8E)-3,7-dimethyl-8-(4-methyl-3,4-dihydro-2H-naphthalen-1-ylidene)octa-2,4,6-trienoic acid
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C21H24O2
 1
1
EC50 = 110 nM
   TI
   LI
   LO
   TS
CP0042977
9-cis retinoic acid
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C20H28O2
 1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
CP0168036
(2E,4E,6Z,8E)-3,7-dimethyl-8-[(4R)-4-methyl-3,4-dihydro-2H-naphthalen-1-ylidene]octa-2,4,6-trienoic acid
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C21H24O2
 1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
CP0347370
(2E,4E,6Z,8E)-3,7-dimethyl-8-[(4S)-4-methyl-3,4-dihydro-2H-naphthalen-1-ylidene]octa-2,4,6-trienoic acid
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C21H24O2
 1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
CP0158206
(2E,4E,6Z,8E)-8-(3,4-dihydro-2H-naphthalen-1-ylidene)-3,7-dimethylocta-2,4,6-trienoic acid
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C20H22O2
 1
1
EC50 = 820 nM
   TI
   LI
   LO
   TS