| Compound ID |
Compound Name |
Compound Formula |
|
CP0080125
|
5-(4-methylphenyl)sulfonylquinolin-8-ol
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|
C16H13NO3S
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0438323
|
7-fluoro-5-(4-methylphenyl)sulfonylquinolin-8-ol
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|
C16H12FNO3S
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0534904
|
5-cyclopentylsulfonylquinolin-8-ol
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|
C14H15NO3S
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0521500
|
5-[4-(trifluoromethyl)phenyl]sulfonylquinolin-8-ol
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|
C16H10F3NO3S
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0159103
|
7-fluoro-5-pyrrolidin-1-ylsulfonylquinolin-8-ol
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|
C13H13FN2O3S
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0404794
|
7-fluoro-5-(4-fluorophenyl)sulfonylquinolin-8-ol
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|
C15H9F2NO3S
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0438319
|
5-ethylsulfonylquinolin-8-ol
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|
C11H11NO3S
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0387334
|
5-(2-benzylpyrrolidin-1-yl)sulfonylquinolin-8-ol
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|
C20H20N2O3S
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0476687
|
5-pyrrolidin-1-ylsulfonylquinolin-8-ol
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|
C13H14N2O3S
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0427211
|
5-cyclopentylsulfonyl-7-fluoroquinolin-8-ol
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|
C14H14FNO3S
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0484717
|
7-methyl-5-pyrrolidin-1-ylsulfonylquinolin-8-ol
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|
C14H16N2O3S
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0519742
|
7-chloro-5-pyrrolidin-1-ylsulfonylquinolin-8-ol
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|
C13H13ClN2O3S
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0438321
|
7-fluoro-5-[4-(trifluoromethyl)phenyl]sulfonylquinolin-8-ol
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|
C16H9F4NO3S
|
1
|
| 1 |
IC50 = 6309.57 nM
|
|
|
|
CP0483087
|
7-chloro-5-cyclopentylsulfonylquinolin-8-ol
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|
C14H14ClNO3S
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0412358
|
7-chloro-5-(4-fluorophenyl)sulfonylquinolin-8-ol
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|
C15H9ClFNO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0438325
|
5-cyclopentylsulfonyl-7-(trifluoromethyl)quinolin-8-ol
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|
C15H14F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0438326
|
7-chloro-5-(4-methylphenyl)sulfonylquinolin-8-ol
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|
C16H12ClNO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0476688
|
5-(4-methylphenyl)sulfonyl-7-(trifluoromethyl)quinolin-8-ol
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|
C17H12F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0567266
|
7-bromo-5-(4-methylphenyl)sulfonylquinolin-8-ol
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|
C16H12BrNO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0355617
|
2-[(2,4-dichlorophenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H14Cl2N2O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0437962
|
2-[(2,6-dimethylphenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C17H20N2O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0437965
|
2-[(2-chlorophenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H15ClN2O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0474014
|
2-[(2-chloro-6-fluorophenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H14ClFN2O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0556289
|
2-benzyl-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H16N2O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
