Brief Information of the Cell Line and Protein
Cell Line ID: CL000424 , LN-18
Synonyms
LN 18
LN18
LN018
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0392
Protein ID: PT03480 , Lysosomal alpha-mannosidase
Gene Name MAN2B1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID O00754
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000424  Protein ID: PT03480
 
Compound ID Compound Name Compound Formula
CP0077627
(-)-swainsonine
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C8H15NO3
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0237947
(3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-phenylethylamino)methyl)-1-methylpyrrolidin-2-one
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C14H20N2O4
 2
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
2
Ki = 3200 nM
   TI
   LI
   LO
   TS
CP0237454
(2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL
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C13H20N2O3
 2
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS
2
Ki = 32500 nM
   TI
   LI
   LO
   TS
CP0281764
(R)-2-(((2R,3R,4R)-3,4-dihydroxy-1-methyl-5-oxopyrrolidin-2-yl)methylamino)-2-phenylethyl 4-bromobenzoate
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C21H23BrN2O5
 1
1
IC50 = 75000 nM
   TI
   LI
   LO
   TS