| Compound ID |
Compound Name |
Compound Formula |
|
CP0579574
|
1-[(3S)-4-[(6R,7R)-7-[3-amino-2-fluoro-5-methyl-6-(trifluoromethyl)phenyl]-6-methyl-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-5,6,7,8-tetrahydroquinazolin-4-yl]-3-methylpiperazin-1-yl]prop-2-en-1-one
Show/Hide
|
C31H40F4N6O2
|
1
|
| 1 |
EC50 = 3.3 nM
|
|
|
|
CP0571968
|
1-[(3S)-4-[(6R,7R)-7-[6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl]-6-methyl-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-5,6,7,8-tetrahydroquinazolin-4-yl]-3-methylpiperazin-1-yl]prop-2-en-1-one
Show/Hide
|
C30H40F3N7O2
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0545985
|
1-[(3S)-4-[(6R,7R)-7-(3-hydroxynaphthalen-1-yl)-6-methyl-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-5,6,7,8-tetrahydroquinazolin-4-yl]-3-methylpiperazin-1-yl]prop-2-en-1-one
Show/Hide
|
C33H41N5O3
|
1
|
| 1 |
EC50 < 6.1 nM
|
|
|
|
CP0573331
|
1-[(3S)-4-[(6R,7R)-7-[3-amino-2-fluoro-6-(trifluoromethyl)phenyl]-6-methyl-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-5,6,7,8-tetrahydroquinazolin-4-yl]-3-methylpiperazin-1-yl]prop-2-en-1-one
Show/Hide
|
C30H38F4N6O2
|
1
|
| 1 |
EC50 = 6.6 nM
|
|
|
|
CP0571092
|
1-[(3S)-4-[(6R,7R)-2-[[(2S,4S)-4-fluoro-1-methylpyrrolidin-2-yl]methoxy]-7-(3-hydroxynaphthalen-1-yl)-6-methyl-5,6,7,8-tetrahydroquinazolin-4-yl]-3-methylpiperazin-1-yl]prop-2-en-1-one
Show/Hide
|
C33H40FN5O3
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0571093
|
1-[(3S)-4-[(7S)-7-(3-hydroxynaphthalen-1-yl)-2-[(1-methylimidazol-4-yl)methoxy]-5,6,7,8-tetrahydroquinazolin-4-yl]-3-methylpiperazin-1-yl]prop-2-en-1-one
Show/Hide
|
C31H34N6O3
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
