Brief Information of the Cell Line and Protein
Cell Line ID: CL000141 , LNCaP
 Cell Line Info 
Synonyms
LNCAP
LNCap
Ln-Cap
Lymph Node Carcinoma of the prostate
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0395
Protein ID: PT03321 , 17-beta-hydroxysteroid dehydrogenase type 3
 Protein Info 
Gene Name HSD17B3
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P37058
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000141
 Cell Line Info 
 Protein ID: PT03321
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0396787
 Compound Info 
(3R,5S,8R,9S,10S,13S,14S)-3-[[2,5-dimethyl-4-[2-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]methyl]-3-hydroxy-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-one
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C33H47F3N2O4S
  1
1
IC50 = 90 nM
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CP0527795
 Compound Info 
(8R,9S,13S,14S)-3-[2,5-dimethyl-4-[2-(trifluoromethyl)phenyl]sulfonylpiperazine-1-carbonyl]-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
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C32H37F3N2O4S
  1
1
IC50 = 100 nM
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CP0443949
 Compound Info 
(8R,9S,13S,14S)-3-[2-[2,5-dimethyl-4-[2-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]ethyl]-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
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C33H41F3N2O3S
  1
1
IC50 = 130 nM
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CP0396785
 Compound Info 
(8R,9S,13S,14S)-2-[[2,5-dimethyl-4-[2-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]methyl]-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
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C32H39F3N2O4S
  1
1
IC50 = 170 nM
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CP0396786
 Compound Info 
(3R,5S,8R,9S,10S,13S,14S,17S)-3-[[2,5-dimethyl-4-[2-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]methyl]-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol
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C33H49F3N2O4S
  1
1
IC50 = 190 nM
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CP0548121
 Compound Info 
(3R,5S,8R,9S,10S,13S,14S,16R)-3-[[2,5-dimethyl-4-[2-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]methyl]-16-fluoro-3-hydroxy-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-one
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C33H46F4N2O4S
  1
1
IC50 = 200 nM
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CP0438075
 Compound Info 
(3R,5S,8R,9S,10S,13S,14S,17E)-3-[[2,5-dimethyl-4-[2-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]methyl]-17-hydroxyimino-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
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C33H48F3N3O4S
  1
1
IC50 = 220 nM
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CP0543823
 Compound Info 
(3R,5S,8R,9R,10S,13S,14S)-3-[[2,5-dimethyl-4-[2-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]methyl]-3-hydroxy-13-methyl-1,2,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one
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C32H45F3N2O4S
  1
1
IC50 = 220 nM
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CP0533524
 Compound Info 
(8R,9S,13S,14S)-3-[2-[2,5-dimethyl-4-[2-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]-1-fluoroethyl]-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
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C33H40F4N2O3S
  1
1
IC50 = 250 nM
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CP0566029
 Compound Info 
1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-[[2,5-dimethyl-4-[2-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]methyl]-3-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone
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C35H51F3N2O4S
  1
1
IC50 = 2600 nM
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