| Compound ID |
Compound Name |
Compound Formula |
|
CP0097086
|
1-[3-[4-(cyclopropanecarbonyl)piperazine-1-carbonyl]-6-fluoroquinolin-4-yl]-4-phenylpiperidine-4-carbonitrile
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|
C30H30FN5O2
|
1
|
| 1 |
EC50 = 1930 nM
|
|
|
|
CP0353601
|
2-[(2-butan-2-yl-3-oxo-2H-imidazo[1,2-c]quinazolin-5-yl)sulfanyl]-N-(2-methylphenyl)butanamide
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|
C25H28N4O2S
|
1
|
| 1 |
EC50 = 2220 nM
|
|
|
|
CP0097088
|
1-[6-fluoro-3-(4-methylsulfonylpiperazine-1-carbonyl)quinolin-4-yl]-4-phenylpiperidine-4-carbonitrile
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|
C27H28FN5O3S
|
6
|
| 1 |
EC50 = 2720 nM
|
|
|
| 2 |
IC50 = 6.5 nM
|
|
|
| 3 |
IC50 = 9.2 nM
|
|
|
| 4 |
IC50 = 25.2 nM
|
|
|
| 5 |
IC50 = 226 nM
|
|
|
| 6 |
IC50 = 848 nM
|
|
|
|
CP0093742
|
ethyl 2-[[4-oxo-3-(3-pyrrolidin-1-ylpropyl)-[1]benzothiolo[3,2-d]pyrimidin-2-yl]sulfanyl]acetate
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|
C21H25N3O3S2
|
1
|
| 1 |
EC50 = 3040 nM
|
|
|
|
CP0364515
|
8-[[4-(cyclopropanecarbonyl)piperazin-1-yl]methyl]-1,3-dimethyl-7-(3-methylbutyl)purine-2,6-dione
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|
C21H32N6O3
|
1
|
| 1 |
EC50 = 7790 nM
|
|
|
|
CP0097087
|
1-[4-[6-fluoro-3-(4-methylsulfonylpiperazine-1-carbonyl)quinolin-4-yl]phenyl]cyclopropane-1-carbonitrile
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|
C25H23FN4O3S
|
6
|
| 1 |
EC50 = 11200 nM
|
|
|
| 2 |
IC50 = 31.8 nM
|
|
|
| 3 |
IC50 = 102 nM
|
|
|
| 4 |
IC50 = 411 nM
|
|
|
| 5 |
IC50 = 870 nM
|
|
|
| 6 |
IC50 = 924 nM
|
|
|
