| Compound ID |
Compound Name |
Compound Formula |
|
CP0426748
|
N-(2,5-dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C21H18Cl2N2O3
|
2
|
| 1 |
EC50 = 128.82 nM
|
|
|
| 2 |
EC50 = 1819.7 nM
|
|
|
|
CP0412085
|
N-(2,5-dichlorophenyl)-2-methyl-5-oxo-4-propyl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C20H22Cl2N2O2
|
1
|
| 1 |
EC50 = 144.54 nM
|
|
|
|
CP0362381
|
4-cyclopentyl-N-(2,5-dichlorophenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C22H24Cl2N2O2
|
1
|
| 1 |
EC50 = 162.18 nM
|
|
|
|
CP0402325
|
N-(2,5-dichlorophenyl)-2-methyl-4-(1,3-oxazol-2-yl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C20H17Cl2N3O3
|
1
|
| 1 |
EC50 = 190.55 nM
|
|
|
|
CP0468915
|
4-(5-bromofuran-2-yl)-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C22H21BrN2O3
|
1
|
| 1 |
EC50 = 245.47 nM
|
|
|
|
CP0468912
|
N-(2,5-dichlorophenyl)-2-methyl-5-oxo-4-(1,3-thiazol-2-yl)-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C20H17Cl2N3O2S
|
1
|
| 1 |
EC50 = 251.19 nM
|
|
|
|
CP0561707
|
4-cyclopropyl-N-(2,5-dichlorophenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C20H20Cl2N2O2
|
1
|
| 1 |
EC50 = 251.19 nM
|
|
|
|
CP0382949
|
4-butyl-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C22H28N2O2
|
2
|
| 1 |
EC50 = 263.03 nM
|
|
|
| 2 |
EC50 = 1380.38 nM
|
|
|
|
CP0537610
|
4-cyclopentyl-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C23H28N2O2
|
1
|
| 1 |
EC50 = 288.4 nM
|
|
|
|
CP0412080
|
4-ethyl-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C20H24N2O2
|
2
|
| 1 |
EC50 = 354.81 nM
|
|
|
| 2 |
EC50 = 4168.69 nM
|
|
|
|
CP0537623
|
4-(furan-2-yl)-N-(2-methoxyphenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C22H22N2O4
|
2
|
| 1 |
EC50 = 371.54 nM
|
|
|
| 2 |
EC50 = 19498.45 nM
|
|
|
|
CP0559360
|
5-cyano-2,6-dimethyl-N-(2-methylphenyl)-4-(2-methylpropyl)-1,4-dihydropyridine-3-carboxamide
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|
C20H25N3O
|
1
|
| 1 |
EC50 = 380.19 nM
|
|
|
|
CP0563600
|
2-methyl-N-(2-methylphenyl)-5-oxo-4-pentyl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C23H30N2O2
|
2
|
| 1 |
EC50 = 398.11 nM
|
|
|
| 2 |
EC50 = 2511.89 nM
|
|
|
|
CP0382948
|
4-butan-2-yl-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C22H28N2O2
|
2
|
| 1 |
EC50 = 501.19 nM
|
|
|
| 2 |
EC50 = 10000 nM
|
|
|
|
CP0164383
|
4-(furan-2-yl)-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C22H22N2O3
|
3
|
| 1 |
EC50 = 524.81 nM
|
|
|
| 2 |
EC50 = 537.03 nM
|
|
|
| 3 |
EC50 = 2238.72 nM
|
|
|
|
CP0382944
|
2-methyl-N-(2-methylphenyl)-4-(2-methylpropyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C22H28N2O2
|
3
|
| 1 |
EC50 = 524.81 nM
|
|
|
| 2 |
EC50 = 2089.3 nM
|
|
|
| 3 |
EC50 = 10000 nM
|
|
|
|
CP0402322
|
4-(furan-3-yl)-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C22H22N2O3
|
2
|
| 1 |
EC50 = 537.03 nM
|
|
|
| 2 |
EC50 = 5754.4 nM
|
|
|
|
CP0434715
|
2-methyl-N-(2-methylphenyl)-5-oxo-4-(2-phenylethyl)-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C26H28N2O2
|
2
|
| 1 |
EC50 = 588.84 nM
|
|
|
| 2 |
EC50 = 61659.5 nM
|
|
|
|
CP0468914
|
4-cyclopropyl-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C21H24N2O2
|
1
|
| 1 |
EC50 = 602.56 nM
|
|
|
|
CP0559426
|
methyl 2-methyl-4-(2-methylpropyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylate
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|
C16H23NO3
|
1
|
| 1 |
EC50 = 616.6 nM
|
|
|
|
CP0402328
|
N-(2-chloro-5-methylphenyl)-2-methyl-5-oxo-4-propyl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C21H25ClN2O2
|
1
|
| 1 |
EC50 = 645.65 nM
|
|
|
|
CP0537624
|
4-(furan-2-yl)-2-methyl-N-(4-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C22H22N2O3
|
2
|
| 1 |
EC50 = 691.83 nM
|
|
|
| 2 |
EC50 = 5370.32 nM
|
|
|
|
CP0438065
|
2-methyl-N-(2-methylphenyl)-5-oxo-4-propyl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C21H26N2O2
|
2
|
| 1 |
EC50 = 691.83 nM
|
|
|
| 2 |
EC50 = 1202.26 nM
|
|
|
|
CP0559404
|
methyl 2,6-dimethyl-5-[(2-methylphenyl)carbamoyl]-4-(2-methylpropyl)-1,4-dihydropyridine-3-carboxylate
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|
C21H28N2O3
|
1
|
| 1 |
EC50 = 691.83 nM
|
|
|
|
CP0561129
|
N-(2-chlorophenyl)-2-methyl-4-(2-methylpropyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C21H25ClN2O2
|
2
|
| 1 |
EC50 = 707.95 nM
|
|
|
| 2 |
EC50 = 3890.45 nM
|
|
|
|
CP0556290
|
2-methyl-N-(2-methylphenyl)-5-oxo-4-[(E)-2-phenylethenyl]-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C26H26N2O2
|
2
|
| 1 |
EC50 = 724.44 nM
|
|
|
| 2 |
EC50 = 45708.82 nM
|
|
|
|
CP0402326
|
N-(2-chlorophenyl)-2-methyl-5-oxo-4-propyl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C20H23ClN2O2
|
1
|
| 1 |
EC50 = 870.96 nM
|
|
|
|
CP0412082
|
4-(1-benzofuran-2-yl)-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C26H24N2O3
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0468913
|
N-(3-chlorophenyl)-2-methyl-5-oxo-4-propyl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C20H23ClN2O2
|
1
|
| 1 |
EC50 = 1071.52 nM
|
|
|
|
CP0412081
|
2-methyl-4-(5-methylfuran-2-yl)-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
EC50 = 1096.48 nM
|
|
|
|
CP0440399
|
N-(2-chloro-5-methoxyphenyl)-2-methyl-5-oxo-4-propyl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C21H25ClN2O3
|
1
|
| 1 |
EC50 = 1096.48 nM
|
|
|
|
CP0438069
|
2-methyl-N-(2-methylphenyl)-5-oxo-4-thiophen-2-yl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C22H22N2O2S
|
3
|
| 1 |
EC50 = 1202.26 nM
|
|
|
| 2 |
EC50 = 1621.81 nM
|
|
|
| 3 |
EC50 = 3019.95 nM
|
|
|
|
CP0382950
|
2-methyl-N-(2-methylphenyl)-5-oxo-4-phenyl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C24H24N2O2
|
2
|
| 1 |
EC50 = 1230.27 nM
|
|
|
| 2 |
EC50 = 17782.79 nM
|
|
|
|
CP0402323
|
4-(3-bromophenyl)-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C24H23BrN2O2
|
2
|
| 1 |
EC50 = 1348.96 nM
|
|
|
| 2 |
EC50 = 3235.94 nM
|
|
|
|
CP0559361
|
2-methyl-N-(2-methylphenyl)-4-(4-methylthiophen-2-yl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C23H24N2O2S
|
1
|
| 1 |
EC50 = 1380.38 nM
|
|
|
|
CP0434703
|
4-(furan-2-yl)-2-methyl-N-(3-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C22H22N2O3
|
2
|
| 1 |
EC50 = 1584.89 nM
|
|
|
| 2 |
EC50 = 4570.88 nM
|
|
|
|
CP0382946
|
4-(4-bromophenyl)-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C24H23BrN2O2
|
2
|
| 1 |
EC50 = 1621.81 nM
|
|
|
| 2 |
EC50 = 3715.35 nM
|
|
|
|
CP0470959
|
N-(2,5-dichlorophenyl)-2-methyl-4-(1,3-oxazol-4-yl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C20H17Cl2N3O3
|
1
|
| 1 |
EC50 = 1659.59 nM
|
|
|
|
CP0537611
|
N-(2,5-dichlorophenyl)-2-methyl-5-oxo-4-(1,3-thiazol-5-yl)-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C20H17Cl2N3O2S
|
1
|
| 1 |
EC50 = 1778.28 nM
|
|
|
|
CP0556294
|
N-(2,5-dichlorophenyl)-2-methyl-5-oxo-4-(1,3-thiazol-4-yl)-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C20H17Cl2N3O2S
|
1
|
| 1 |
EC50 = 1949.84 nM
|
|
|
|
CP0550954
|
2-methyl-N-(2-methylphenyl)-5-oxo-4-[3-(trifluoromethyl)phenyl]-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C25H23F3N2O2
|
2
|
| 1 |
EC50 = 2818.38 nM
|
|
|
| 2 |
EC50 = 15488.17 nM
|
|
|
|
CP0561127
|
2-ethyl-4-(furan-2-yl)-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
EC50 = 3388.44 nM
|
|
|
|
CP0402320
|
4-(furan-2-yl)-2-methyl-5-oxo-N-phenyl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C21H20N2O3
|
2
|
| 1 |
EC50 = 3548.13 nM
|
|
|
| 2 |
EC50 = 7762.47 nM
|
|
|
|
CP0470958
|
2-methyl-N-(2-methylphenyl)-4-(4-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C25H26N2O2
|
2
|
| 1 |
EC50 = 3630.78 nM
|
|
|
| 2 |
EC50 = 30199.52 nM
|
|
|
|
CP0382945
|
N-(2-iodophenyl)-2-methyl-4-(2-methylpropyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C21H25IN2O2
|
2
|
| 1 |
EC50 = 3890.45 nM
|
|
|
| 2 |
EC50 = 6760.83 nM
|
|
|
|
CP0434702
|
2-methyl-N-(2-methylphenyl)-5-oxo-4-[4-(trifluoromethyl)phenyl]-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C25H23F3N2O2
|
2
|
| 1 |
EC50 = 4897.79 nM
|
|
|
| 2 |
EC50 = 7585.78 nM
|
|
|
|
CP0561706
|
4-cyclohexyl-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
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|
C24H30N2O2
|
1
|
| 1 |
EC50 = 5495.41 nM
|
|
|
|
CP0421671
|
N-(2,3-dimethylphenyl)-2-methyl-4-(2-methylpropyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C23H30N2O2
|
2
|
| 1 |
EC50 = 5495.41 nM
|
|
|
| 2 |
EC50 = 10471.29 nM
|
|
|
|
CP0382947
|
4-(4-ethylphenyl)-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C26H28N2O2
|
2
|
| 1 |
EC50 = 6760.83 nM
|
|
|
| 2 |
EC50 = 83176.38 nM
|
|
|
|
CP0550946
|
4-(1-benzothiophen-3-yl)-2-methyl-N-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C26H24N2O2S
|
1
|
| 1 |
EC50 = 7762.47 nM
|
|
|
|
CP0402321
|
N-(2,6-difluorophenyl)-2-methyl-4-(2-methylpropyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C21H24F2N2O2
|
2
|
| 1 |
EC50 = 10471.29 nM
|
|
|
| 2 |
EC50 = 21379.62 nM
|
|
|
|
CP0075552
|
CH3-CH2-COOH
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|
C3H6O2
|
2
|
| 1 |
EC50 = 10715.19 nM
|
|
|
| 2 |
EC50 = 11748.98 nM
|
|
|
|
CP0559425
|
N-(2,5-dichlorophenyl)-2-methyl-5-oxo-4-(2-pyrazol-1-ylethyl)-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C22H22Cl2N4O2
|
1
|
| 1 |
EC50 = 11220.18 nM
|
|
|
|
CP0537612
|
1-methylcyclopropane-1-carboxylic acid
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|
C5H8O2
|
1
|
| 1 |
EC50 = 22387.21 nM
|
|
|
|
CP0470961
|
2-methyl-N-(2-methylphenyl)-4-(1-methylpyrrol-2-yl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
Show/Hide
|
C23H25N3O2
|
1
|
| 1 |
EC50 = 35481.34 nM
|
|
|
|
CP0559820
|
3-benzoyl-2-methyl-4-(2-methylpropyl)-4,6,7,8-tetrahydro-1H-quinolin-5-one
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|
C21H25NO2
|
1
|
| 1 |
EC50 < 100000 nM
|
|
|
