| Compound ID |
Compound Name |
Compound Formula |
|
CP0526223
|
N-(2,6-dimethylphenyl)-4-[[4-[4-(trifluoromethoxy)phenyl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C27H20F6N4O2
|
1
|
| 1 |
IC50 = 0.53 nM
|
|
|
|
CP0526761
|
N-(2,6-dimethylphenyl)-4-[(5-methyl-4-pyridin-4-ylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C25H23N5O
|
1
|
| 1 |
IC50 = 0.54 nM
|
|
|
|
CP0405957
|
N-(2,6-dimethylphenyl)-4-[[4-propyl-6-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C29H27F3N4O2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0525609
|
N-(2-methylphenyl)-4-[[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C26H21F3N4O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0471648
|
N-[5-[[benzyl(methyl)amino]methyl]-2-methylphenyl]-4-[[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C35H32F3N5O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0525640
|
N-[2-methyl-5-(1-methylpyrazol-4-yl)phenyl]-4-[[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C30H25F3N6O2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0554505
|
N-(2,6-dimethylphenyl)-4-[[4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C26H21F3N4O2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0555888
|
N-(2,6-dimethylphenyl)-4-[[5-methyl-4-[3-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C27H23F3N4O2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0461913
|
4-[[5-cyclopropyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]-N-(2,6-dimethylphenyl)benzamide
Show/Hide
|
C29H25F3N4O2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0487783
|
N-(2,6-dimethylphenyl)-4-[[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C27H23F3N4O2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0555880
|
N-(2,6-dimethylphenyl)-4-[(5-methyl-4-phenylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C26H24N4O
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0524971
|
N-(2,6-dimethylphenyl)-4-[[4-methyl-6-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C27H23F3N4O2
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0387940
|
N-(2,6-dimethylphenyl)-4-[[4,5-dimethyl-6-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C28H25F3N4O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0524970
|
N-(2,6-dimethylphenyl)-4-[[4-[4-(trifluoromethoxy)phenyl]pyridin-2-yl]amino]benzamide
Show/Hide
|
C27H22F3N3O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0530982
|
N-(2,6-dimethylphenyl)-4-[[5-fluoro-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C26H20F4N4O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0524973
|
N-(2,6-dimethylphenyl)-4-[[4-(4-fluorophenyl)-5-methylpyrimidin-2-yl]amino]benzamide
Show/Hide
|
C26H23FN4O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0530983
|
N-cyclohexyl-4-[[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C25H25F3N4O2
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0405960
|
N-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-4-[[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C31H31F3N6O2
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0525610
|
N-(2,6-dimethylphenyl)-4-[methyl-[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C28H25F3N4O2
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0387965
|
4-[[4-(4-cyanophenyl)-5-methylpyrimidin-2-yl]amino]-N-(2,6-dimethylphenyl)benzamide
Show/Hide
|
C27H23N5O
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0523160
|
3-methoxy-1-methyl-4-oxo-5-phenacyl-N-(2-pyrrolidin-1-ylethyl)pyrrolo[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C28H30N4O4
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0396573
|
6-ethyl-N-[1-(2-hydroxyacetyl)piperidin-4-yl]-1-methyl-4-oxo-5-phenacyl-3-(2,2,2-trifluoroethoxy)pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C28H31F3N4O6
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0499993
|
3-(2,2-difluoroethoxy)-6-ethyl-N-[1-(2-hydroxyacetyl)piperidin-4-yl]-1-methyl-4-oxo-5-phenacylpyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C28H32F2N4O6
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0089559
|
N-[1-(2-hydroxyacetyl)piperidin-4-yl]-3-methoxy-1-methyl-4-oxo-5-phenacylpyrrolo[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C29H30N4O6
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0488534
|
6-ethyl-3-(2-fluoroethoxy)-N-[1-(2-hydroxyacetyl)piperidin-4-yl]-1-methyl-4-oxo-5-phenacylpyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C28H33FN4O6
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0526706
|
3-methoxy-4-oxo-5-phenacyl-N-(2-pyrrolidin-1-ylethyl)thieno[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C27H27N3O4S
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
|
CP0487775
|
N-(2,6-dimethylphenyl)-4-[[5-ethyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C28H25F3N4O2
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0413910
|
ERISMODEGIB
Show/Hide
|
C26H26F3N3O3
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0499562
|
6-ethyl-N-[1-(2-hydroxyacetyl)piperidin-4-yl]-3-methoxy-1-methyl-4-oxo-5-phenacylpyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C27H32N4O6
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0341938
|
N-[1-(2-hydroxyethyl)piperidin-4-yl]-3-methoxy-1-methyl-4-oxo-5-phenacylpyrrolo[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C29H32N4O5
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0538415
|
3-ethoxy-6-ethyl-N-[1-(2-hydroxyacetyl)piperidin-4-yl]-1-methyl-4-oxo-5-phenacylpyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C28H34N4O6
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0502890
|
3-ethoxy-1-methyl-4-oxo-5-phenacyl-N-(2-pyrrolidin-1-ylethyl)pyrrolo[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C29H32N4O4
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0068085
|
2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide
Show/Hide
|
C19H14Cl2N2O3S
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0463576
|
3-methoxy-1-methyl-4-oxo-5-phenacyl-N-(2-piperidin-1-ylethyl)pyrrolo[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C29H32N4O4
|
1
|
| 1 |
IC50 = 9.6 nM
|
|
|
|
CP0405962
|
N-(2,6-dimethylphenyl)-4-[[5-methyl-4-(1-methylpyrazol-4-yl)pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C24H24N6O
|
1
|
| 1 |
IC50 = 10.6 nM
|
|
|
|
CP0396575
|
N-[1-(2-hydroxyacetyl)piperidin-4-yl]-3-methoxy-1,6-dimethyl-4-oxo-5-phenacylpyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C26H30N4O6
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0387956
|
N-(2,6-dimethylphenyl)-4-[[4-(furan-3-yl)-5-methylpyrimidin-2-yl]amino]benzamide
Show/Hide
|
C24H22N4O2
|
1
|
| 1 |
IC50 = 15.7 nM
|
|
|
|
CP0487782
|
N-(2,6-dimethylphenyl)-4-[[5-methyl-4-(4-morpholin-4-ylphenyl)pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C30H31N5O2
|
1
|
| 1 |
IC50 = 20.2 nM
|
|
|
|
CP0526943
|
3-methoxy-1-methyl-4-oxo-5-phenacyl-N-piperidin-4-ylpyrrolo[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C27H28N4O4
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0523161
|
3-methoxy-1-methyl-N-(2-morpholin-4-ylethyl)-4-oxo-5-phenacylpyrrolo[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C28H30N4O5
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0461911
|
N-(2,6-dimethylphenyl)-4-[[6-[4-(trifluoromethoxy)phenyl]pyridin-2-yl]amino]benzamide
Show/Hide
|
C27H22F3N3O2
|
1
|
| 1 |
IC50 = 23.4 nM
|
|
|
|
CP0526759
|
4-[(4-cyclopropyl-5-methylpyrimidin-2-yl)amino]-N-(2,6-dimethylphenyl)benzamide
Show/Hide
|
C23H24N4O
|
1
|
| 1 |
IC50 = 32.8 nM
|
|
|
|
CP0525641
|
4-[(4-benzyl-5-methylpyrimidin-2-yl)amino]-N-(2,6-dimethylphenyl)benzamide
Show/Hide
|
C27H26N4O
|
1
|
| 1 |
IC50 = 34.3 nM
|
|
|
|
CP0566186
|
2-methyl-N-[4-[[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]phenyl]benzamide
Show/Hide
|
C26H21F3N4O2
|
1
|
| 1 |
IC50 = 42.1 nM
|
|
|
|
CP0524972
|
4-[[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]-N-propan-2-ylbenzamide
Show/Hide
|
C22H21F3N4O2
|
1
|
| 1 |
IC50 = 73.1 nM
|
|
|
|
CP0396574
|
3,6-diethyl-N-[1-(2-hydroxyacetyl)piperidin-4-yl]-1-methyl-4-oxo-5-phenacylpyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C28H34N4O5
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0381195
|
N-[1-(2-hydroxyacetyl)piperidin-4-yl]-3-methoxy-1-methyl-4-oxo-5-phenacyl-6,7,8,9-tetrahydropyrrolo[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C29H34N4O6
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0394970
|
N-[5-[[benzyl(methyl)amino]methyl]-2-methylphenyl]-4-[(4,5-dimethylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C29H31N5O
|
1
|
| 1 |
IC50 = 100.6 nM
|
|
|
|
CP0467466
|
N-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-4-[[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C31H31F3N6O2
|
1
|
| 1 |
IC50 = 118.3 nM
|
|
|
|
CP0553426
|
N-[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]-1H-indazol-5-amine
Show/Hide
|
C19H14F3N5O
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0433559
|
N-[1-(2-hydroxyethyl)piperidin-4-yl]-3-methoxy-1-methyl-4-oxo-5-(2-phenylethyl)pyrrolo[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C29H34N4O4
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0555879
|
N-(2,6-dimethylphenyl)-4-[(4,5-dimethylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C21H22N4O
|
1
|
| 1 |
IC50 = 151.5 nM
|
|
|
|
CP0526762
|
N-(2,6-dimethylphenyl)-4-[[4-[3-fluoro-4-(trifluoromethoxy)phenyl]-5-methylpyrimidin-2-yl]amino]benzamide
Show/Hide
|
C27H22F4N4O2
|
1
|
| 1 |
IC50 = 158.5 nM
|
|
|
|
CP0526758
|
N-[2-[(4-methylpiperazin-1-yl)methyl]phenyl]-4-[[5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C31H31F3N6O2
|
1
|
| 1 |
IC50 = 353.6 nM
|
|
|
|
CP0508589
|
N-[1-(2-hydroxyethyl)piperidin-4-yl]-3-methoxy-1-methyl-4-oxo-5-(2-oxobutyl)pyrrolo[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C25H32N4O5
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0526760
|
N-(2,6-dimethylphenyl)-4-[(5-methyl-4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C25H23N5O
|
1
|
| 1 |
IC50 > 500 nM
|
|
|
|
CP0530984
|
N-(2,6-dimethylphenyl)-4-[[5-methyl-4-[2-(trifluoromethoxy)phenyl]pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C27H23F3N4O2
|
1
|
| 1 |
IC50 > 500 nM
|
|
|
|
CP0540364
|
N-(2,6-dimethylphenyl)-4-[[5-methyl-4-(4-methylphenyl)pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C27H26N4O
|
1
|
| 1 |
IC50 > 500 nM
|
|
|
|
CP0553425
|
N-[6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl]-5-methyl-4-[4-(trifluoromethoxy)phenyl]pyrimidin-2-amine
Show/Hide
|
C23H24F3N5O2
|
1
|
| 1 |
IC50 > 500 nM
|
|
|
|
CP0462372
|
3-methoxy-4-oxo-5-phenacyl-N-(2-pyrrolidin-1-ylethyl)furo[3,2-c]quinoline-2-carboxamide
Show/Hide
|
C27H27N3O5
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
