Brief Information of the Cell Line and Protein
Cell Line ID: CL000043 , U2OS
 Cell Line Info 
Synonyms
U-2 OS
U-2OS
U-2-OS
U2-OS
U20-S
U20S
2T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0042
Protein ID: PT02680 , Phosphatidylinositol 3-kinase catalytic subunit type 3
 Protein Info 
Gene Name PIK3C3
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q8NEB9
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000043
 Cell Line Info 
 Protein ID: PT02680
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0102496
 Compound Info 
4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-amine
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C17H17N7
  1
1
IC50 = 12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0058491
 Compound Info 
4-(cyclopropylmethyl)-N-methyl-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-amine
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C18H19N7
  1
1
IC50 = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0058485
 Compound Info 
1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methylpropan-2-ol
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C21H25N7O
  1
1
IC50 = 25 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0079006
 Compound Info 
4-(cyclopropylmethyl)-N-(oxan-4-yl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-amine
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C22H25N7O
  1
1
IC50 = 270 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0174724
 Compound Info 
4-[4-(cyclopropylmethyl)pyrimidin-5-yl]-N-pyridin-4-ylpyrimidin-2-amine
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C17H16N6
  1
1
IC50 = 330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS