| Compound ID |
Compound Name |
Compound Formula |
|
CP0492817
|
(3S)-3-[4-[[3-methyl-4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C34H35NO3
|
1
|
| 1 |
EC50 = 0.54 nM
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|
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CP0422249
|
(3S)-3-[4-[[4-[[1-methyl-5-(trifluoromethyl)spiro[2H-indole-3,4'-piperidine]-1'-yl]methyl]phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C34H35F3N2O3
|
1
|
| 1 |
EC50 = 0.59 nM
|
|
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CP0425647
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(3S)-3-[4-[[4-[(1-phenylspiro[2H-indole-3,4'-piperidine]-1'-yl)methyl]phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C38H38N2O3
|
1
|
| 1 |
EC50 = 0.83 nM
|
|
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CP0426505
|
(3S)-3-[4-[[4-[(7-chloro-1-methylspiro[2H-indole-3,4'-piperidine]-1'-yl)methyl]phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C33H35ClN2O3
|
1
|
| 1 |
EC50 = 0.89 nM
|
|
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CP0426504
|
(3S)-3-[4-[[5-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)thiophen-2-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C31H31NO3S
|
1
|
| 1 |
EC50 = 0.93 nM
|
|
|
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CP0532759
|
(3S)-3-[4-[[3-chloro-4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C33H32ClNO3
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
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CP0425645
|
(3S)-3-[4-[[4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)-3-(trifluoromethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C34H32F3NO3
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
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CP0546043
|
(3S)-3-[4-[[4-methyl-5-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)thiophen-2-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C32H33NO3S
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
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CP0422242
|
(3S)-3-[4-[[4-(spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C33H35NO3
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
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CP0422245
|
(3S)-3-[4-[[3-fluoro-4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C33H32FNO3
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
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CP0010598
|
(3S)-3-[4-[[5-(spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylmethyl)thiophen-2-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C31H33NO3S
|
1
|
| 1 |
EC50 = 1.7 nM
|
|
|
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CP0013323
|
(3S)-3-[4-[[4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C33H33NO3
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
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CP0538129
|
(3S)-3-[4-[[4-[(1-propan-2-ylspiro[2H-indole-3,4'-piperidine]-1'-yl)methyl]phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C35H40N2O3
|
1
|
| 1 |
EC50 = 2.1 nM
|
|
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CP0008406
|
(3S)-3-[4-[[5-[(8-methoxy-3,4-dihydro-2H-quinolin-1-yl)methyl]thiophen-2-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C28H29NO4S
|
1
|
| 1 |
EC50 = 3 nM
|
|
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CP0471349
|
(3S)-3-[4-[[3-methoxy-4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C34H35NO4
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0179633
|
AMG-837
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|
C26H21F3O3
|
1
|
| 1 |
EC50 = 3.2 nM
|
|
|
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CP0422239
|
(3S)-3-[4-[[5-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)furan-2-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C31H31NO4
|
1
|
| 1 |
EC50 = 4.2 nM
|
|
|
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CP0422243
|
(3S)-3-[4-[[4-[(4-oxospiro[3H-chromene-2,4'-piperidine]-1'-yl)methyl]phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C33H33NO5
|
1
|
| 1 |
EC50 = 4.5 nM
|
|
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CP0422248
|
(3S)-3-[4-[[4-[(1,5-dimethylspiro[2H-indole-3,4'-piperidine]-1'-yl)methyl]phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C34H38N2O3
|
1
|
| 1 |
EC50 = 4.6 nM
|
|
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CP0492793
|
(3S)-3-[4-[[4-[(1-methylspiro[2H-indole-3,4'-piperidine]-1'-yl)methyl]phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C33H36N2O3
|
1
|
| 1 |
EC50 = 5.5 nM
|
|
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CP0425644
|
(3S)-3-[4-[[2-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)-1,3-thiazol-5-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C30H30N2O3S
|
1
|
| 1 |
EC50 = 11 nM
|
|
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CP0098306
|
(3S)-3-[4-[[2-(2,6-dimethylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C27H25N3O3
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
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CP0425642
|
(3R)-3-[2-fluoro-4-[[4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
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|
C33H32FNO3
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
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CP0422241
|
(3S)-3-[4-[[4-methyl-5-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)-1,3-thiazol-2-yl]methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C31H32N2O3S
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
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CP0511744
|
(3S)-3-[4-[[4-[(5-methoxy-1-methylspiro[2H-indole-3,4'-piperidine]-1'-yl)methyl]phenyl]methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C34H38N2O4
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
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CP0492791
|
(3S)-3-[4-[[5-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)-1,3-thiazol-2-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C30H30N2O3S
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
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CP0407280
|
(3S)-3-[4-[[2-(4-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C28H27N3O3
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
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CP0104146
|
2-[(3S)-6-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
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|
C29H32O7S
|
1
|
| 1 |
EC50 = 36 nM
|
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CP0402869
|
(3S)-3-[4-[[2-[4-(3-hydroxy-3-methylbutoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C30H31N3O5
|
1
|
| 1 |
EC50 = 68 nM
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CP0415364
|
(3S)-3-[4-[[2-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C31H33N3O6S
|
1
|
| 1 |
EC50 = 95 nM
|
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CP0402867
|
(3S)-3-[4-[[2-[4-(difluoromethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C26H21F2N3O4
|
1
|
| 1 |
EC50 = 98 nM
|
|
|
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CP0422240
|
(3S)-3-[4-[[4-methyl-2-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)-1,3-thiazol-5-yl]methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C31H32N2O3S
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
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CP0532749
|
(3R)-3-[4-[[4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C33H33NO3
|
1
|
| 1 |
EC50 = 120 nM
|
|
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CP0471351
|
3-[2-fluoro-4-[[4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]propanoic acid
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|
C30H30FNO3
|
1
|
| 1 |
EC50 = 160 nM
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CP0419788
|
(3S)-3-[4-[[2-(4-cyanophenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C26H20N4O3
|
1
|
| 1 |
EC50 = 216 nM
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CP0426503
|
(3S)-3-[2-fluoro-4-[[4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C33H32FNO3
|
1
|
| 1 |
EC50 = 420 nM
|
|
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CP0422238
|
3-[2-chloro-4-[[4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]propanoic acid
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|
C30H30ClNO3
|
1
|
| 1 |
EC50 = 540 nM
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CP0415365
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(3S)-3-[4-[[2-[4-(2-methoxyethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acid
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|
C28H27N3O5
|
1
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| 1 |
EC50 = 562 nM
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CP0425646
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(3S)-3-(1,2-oxazol-3-yl)-3-[4-[(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)methoxy]phenyl]propanoic acid
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|
C25H20N4O4
|
1
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| 1 |
EC50 = 14000 nM
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CP0006743
|
4-methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide
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|
C16H19NO3S
|
1
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| 1 |
EC50 > 31622.78 nM
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