Brief Information of the Cell Line and Protein
Cell Line ID: CL000043 , U2OS
Synonyms
U-2 OS
U-2OS
U-2-OS
U2-OS
U20-S
U20S
2T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0042
Protein ID: PT02509 , G-protein coupled bile acid receptor 1
Gene Name GPBAR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q8TDU6
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000043  Protein ID: PT02509
 
Compound ID Compound Name Compound Formula
CP0494057
N-(4-chlorophenyl)-3-(3-methoxyphenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C19H17ClN2O3
 1
1
EC50 = 1 nM
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CP0404303
3-(2-chlorophenyl)-N-(4-chlorophenyl)-5-cyclopropyl-N-methyl-1,2-oxazole-4-carboxamide
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C20H16Cl2N2O2
 1
1
EC50 = 3.981 nM
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CP0501394
3-(2-chlorophenyl)-N-(4-chlorophenyl)-5-ethyl-N-methyl-1,2-oxazole-4-carboxamide
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C19H16Cl2N2O2
 1
1
EC50 = 3.981 nM
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CP0387156
N-(4-chlorophenyl)-3-(3-fluorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14ClFN2O2
 1
1
EC50 = 7.943 nM
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CP0497489
3-(2-chlorophenyl)-N-(4-chlorophenyl)-N-methyl-5-propyl-1,2-oxazole-4-carboxamide
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C20H18Cl2N2O2
 1
1
EC50 = 10 nM
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CP0526817
3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diethyl-1,2-oxazole-4-carboxamide
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C20H18Cl2N2O2
 1
1
EC50 = 10 nM
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CP0392778
N-(4-chlorophenyl)-5-ethyl-N-methyl-3-phenyltriazole-4-carboxamide
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C18H17ClN4O
 1
1
EC50 = 12.59 nM
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CP0404264
3-(3-chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14Cl2N2O2
 1
1
EC50 = 12.59 nM
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CP0417931
3-(2-chlorophenyl)-N-(3,5-dibromo-4-methylphenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C19H15Br2ClN2O2
 1
1
EC50 = 12.59 nM
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CP0497494
N-(4-chlorophenyl)-N,5-dimethyl-3-(2-methylphenyl)-1,2-oxazole-4-carboxamide
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C19H17ClN2O2
 1
1
EC50 = 12.59 nM
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CP0524009
N,3-bis(4-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14Cl2N2O2
 1
1
EC50 = 12.59 nM
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CP0469859
N-(4-bromophenyl)-3-(2-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14BrClN2O2
 1
1
EC50 = 15.85 nM
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CP0429182
N-(4-chlorophenyl)-N,5-dimethyl-3-phenyl-1,2-oxazole-4-carboxamide
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C18H15ClN2O2
 1
1
EC50 = 19.95 nM
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CP0447482
3-(2-chlorophenyl)-N,5-dimethyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
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C19H14ClF3N2O2
 1
1
EC50 = 19.95 nM
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CP0510591
3-(2-chlorophenyl)-N-(4-chlorophenyl)-N-methyl-5-propan-2-yl-1,2-oxazole-4-carboxamide
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C20H18Cl2N2O2
 1
1
EC50 = 19.95 nM
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CP0524007
3-(2-chlorophenyl)-N-(3,4-dimethylphenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C20H19ClN2O2
 1
1
EC50 = 19.95 nM
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CP0194642
3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14Cl2N2O2
 1
1
EC50 = 31.62 nM
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CP0447487
3-(2-chlorophenyl)-N-(4-chlorophenyl)-N-ethyl-5-methyl-1,2-oxazole-4-carboxamide
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C19H16Cl2N2O2
 1
1
EC50 = 31.62 nM
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CP0522075
N-(4-chlorophenyl)-N,5-dimethyl-3-[2-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
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C19H14ClF3N2O2
 1
1
EC50 = 31.62 nM
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CP0520575
3-(2-chlorophenyl)-N-(4-chlorophenyl)-5-methyl-N-propan-2-yl-1,2-oxazole-4-carboxamide
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C20H18Cl2N2O2
 1
1
EC50 = 39.81 nM
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CP0417989
N-(4-chloro-3-methylphenyl)-3-(2-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C19H16Cl2N2O2
 1
1
EC50 = 63.1 nM
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CP0479785
N-(4-chlorophenyl)-5-ethyl-N-methyl-3-phenyl-1,2-oxazole-4-carboxamide
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C19H17ClN2O2
 1
1
EC50 = 63.1 nM
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CP0520547
N-(4-chlorophenyl)-3-(2-methoxyphenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C19H17ClN2O3
 1
1
EC50 = 63.1 nM
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CP0191568
N-(3-chloro-4-methylphenyl)-3-(2-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C19H16Cl2N2O2
 1
1
EC50 = 79.43 nM
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CP0522074
N-(4-chlorophenyl)-N,5-dimethyl-3-(3-methylphenyl)-1,2-oxazole-4-carboxamide
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C19H17ClN2O2
 1
1
EC50 = 79.43 nM
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CP0524006
3-(2-chlorophenyl)-N-(3,4-dichlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H13Cl3N2O2
 1
1
EC50 = 100 nM
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CP0447465
3-(2-chlorophenyl)-N-(4-iodophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14ClIN2O2
 1
1
EC50 = 125.89 nM
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CP0479806
3-(2-chlorophenyl)-N,5-dimethyl-N-(4-methylphenyl)-1,2-oxazole-4-carboxamide
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C19H17ClN2O2
 1
1
EC50 = 125.89 nM
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CP0499351
N-(4-chlorophenyl)-3-(2-fluorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14ClFN2O2
 1
1
EC50 = 158.49 nM
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CP0447479
N-(4-chloro-2-methylphenyl)-3-(2-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C19H16Cl2N2O2
 1
1
EC50 = 251.19 nM
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CP0375670
3-(2-chlorophenyl)-N-(4-chlorophenyl)-5-methyl-N-propyl-1,2-oxazole-4-carboxamide
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C20H18Cl2N2O2
 1
1
EC50 = 316.23 nM
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CP0447483
3-(2-chlorophenyl)-N,5-dimethyl-N-[4-(trifluoromethoxy)phenyl]-1,2-oxazole-4-carboxamide
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C19H14ClF3N2O3
 1
1
EC50 = 316.23 nM
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CP0501417
N-(4-chlorophenyl)-N,5-dimethyl-3-[3-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
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C19H14ClF3N2O2
 1
1
EC50 = 316.23 nM
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CP0517604
3-(2-chlorophenyl)-N-(4-cyanophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C19H14ClN3O2
 1
1
EC50 = 316.23 nM
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CP0404262
3-(2-chlorophenyl)-N-(4-methoxyphenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C19H17ClN2O3
 1
1
EC50 = 398.11 nM
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CP0430586
3-(2-chlorophenyl)-N,5-dimethyl-N-(2-methylphenyl)-1,2-oxazole-4-carboxamide
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C19H17ClN2O2
 1
1
EC50 = 398.11 nM
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CP0404261
3-(2-chlorophenyl)-N-(4-fluorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14ClFN2O2
 1
1
EC50 = 501.19 nM
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CP0479681
N-(4-chlorophenyl)-3-(4-fluorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14ClFN2O2
 1
1
EC50 = 501.19 nM
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CP0387152
3-(2-chlorophenyl)-N-(3-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14Cl2N2O2
 1
1
EC50 = 630.96 nM
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CP0447486
N-(4-chlorophenyl)-3-(2,6-dichlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H13Cl3N2O2
 1
1
EC50 = 630.96 nM
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CP0501411
3-(2-chlorophenyl)-N-(3-fluorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14ClFN2O2
 1
1
EC50 = 630.96 nM
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CP0524010
3-(2-chloro-6-fluorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H13Cl2FN2O2
 1
1
EC50 = 630.96 nM
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CP0373471
3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-di(propan-2-yl)-1,2-oxazole-4-carboxamide
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C22H22Cl2N2O2
 1
1
EC50 = 794.33 nM
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CP0447485
N-(4-chlorophenyl)-N,5-dimethyl-3-(4-methylphenyl)-1,2-oxazole-4-carboxamide
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C19H17ClN2O2
 1
1
EC50 = 1000 nM
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CP0501413
3-(2-chlorophenyl)-N-(4-ethylphenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C20H19ClN2O2
 1
1
EC50 = 1000 nM
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CP0387159
N-(4-chlorophenyl)-N,5-dimethyl-3-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
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C19H14ClF3N2O2
 1
1
EC50 = 1258.93 nM
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CP0417929
3-(2-chlorophenyl)-N-(3-methoxyphenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C19H17ClN2O3
 1
1
EC50 = 1258.93 nM
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CP0447481
3-(2-chlorophenyl)-N,5-dimethyl-N-(4-propan-2-ylphenyl)-1,2-oxazole-4-carboxamide
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C21H21ClN2O2
 1
1
EC50 = 1258.93 nM
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CP0479783
3-(2-chlorophenyl)-N-(4-chlorophenyl)-N-methyl-1,2-oxazole-4-carboxamide
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C17H12Cl2N2O2
 1
1
EC50 = 1258.93 nM
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CP0497492
3-(2-chlorophenyl)-N,5-dimethyl-N-(3-methylphenyl)-1,2-oxazole-4-carboxamide
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C19H17ClN2O2
 1
1
EC50 = 1258.93 nM
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CP0521444
N,3-bis(2-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14Cl2N2O2
 1
1
EC50 = 1995.26 nM
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CP0375667
3-(2-chlorophenyl)-N-(2-fluorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H14ClFN2O2
 1
1
EC50 = 2511.89 nM
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CP0417928
3-(2-chlorophenyl)-N-(2-methoxyphenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C19H17ClN2O3
 1
1
EC50 = 2511.89 nM
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CP0447480
3-(2-chlorophenyl)-N-(2,4-dichlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C18H13Cl3N2O2
 1
1
EC50 = 2511.89 nM
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CP0375669
3-(2-chlorophenyl)-N-(4-chlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide
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C17H12Cl2N2O2
 1
1
EC50 = 3162.28 nM
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CP0404304
(5-chloro-2,3-dihydroindol-1-yl)-[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]methanone
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C19H14Cl2N2O2
 1
1
EC50 = 3162.28 nM
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CP0527076
3-(2-chlorophenyl)-N-(4-chlorophenyl)-N-cyclopropyl-5-methyl-1,2-oxazole-4-carboxamide
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C20H16Cl2N2O2
 1
1
EC50 = 3162.28 nM
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CP0497493
3-(2-chlorophenyl)-N-[4-(dimethylamino)phenyl]-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C20H20ClN3O2
 1
1
EC50 = 3981.07 nM
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CP0517603
3-(2-chlorophenyl)-N,5-dimethyl-N-phenyl-1,2-oxazole-4-carboxamide
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C18H15ClN2O2
 1
1
EC50 = 3981.07 nM
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CP0404260
3-(2-chlorophenyl)-N-(3-chlorophenyl)-N-ethyl-5-methyl-1,2-oxazole-4-carboxamide
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C19H16Cl2N2O2
 1
1
EC50 = 5011.87 nM
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CP0501415
N-(4-chlorophenyl)-3-(4-methoxyphenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C19H17ClN2O3
 1
1
EC50 = 5011.87 nM
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CP0501414
3-(2-chlorophenyl)-N,5-dimethyl-N-(4-propylphenyl)-1,2-oxazole-4-carboxamide
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C21H21ClN2O2
 1
1
EC50 = 6309.57 nM
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CP0447484
methyl 4-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-methylamino]benzoate
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C20H17ClN2O4
 1
1
EC50 = 7943.28 nM
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CP0524008
N-(4-tert-butylphenyl)-3-(2-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C22H23ClN2O2
 1
1
EC50 = 7943.28 nM
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CP0499350
N-(4-acetylphenyl)-3-(2-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
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C20H17ClN2O3
 1
1
EC50 = 12589.25 nM
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CP0479809
3-(2-chlorophenyl)-N,5-dimethyl-N-(4-methylsulfonylphenyl)-1,2-oxazole-4-carboxamide
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C19H17ClN2O4S
 1
1
EC50 > 7943.28 nM
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