| Compound ID |
Compound Name |
Compound Formula |
|
CP0465621
|
tert-butyl 3-[5-[(4-methylsulfonylphenyl)methoxy]pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octane-8-carboxylate
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|
C23H30N4O5S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0444026
|
tert-butyl 3-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octane-8-carboxylate
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|
C22H26N6O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0436224
|
(2,2,3,3-tetrafluorocyclobutyl) 3-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octane-8-carboxylate
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|
C22H20F4N6O3
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0515235
|
tert-butyl 8-[5-[(4-methylsulfonylphenyl)methoxy]pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octane-3-carboxylate
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|
C23H30N4O5S
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0259933
|
tert-butyl (3R)-4-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]-3-methylpiperazine-1-carboxylate
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|
C21H26N6O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0055446
|
2,2,2-trifluoroethyl 3-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octane-8-carboxylate
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|
C20H19F3N6O3
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0385919
|
4-[[2-[8-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)-3,8-diazabicyclo[3.2.1]octan-3-yl]pyrimidin-5-yl]oxymethyl]pyridine-3-carbonitrile
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|
C22H24N8O2
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0247411
|
tert-butyl (3R)-3-methyl-4-[5-[(4-methylsulfonylphenyl)methoxy]pyrimidin-2-yl]piperazine-1-carboxylate
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|
C22H30N4O5S
|
1
|
| 1 |
IC50 = 129 nM
|
|
|
|
CP0385918
|
tert-butyl 4-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]piperazine-1-carboxylate
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|
C20H24N6O3
|
1
|
| 1 |
IC50 = 507 nM
|
|
|
|
CP0259466
|
tert-butyl 4-[5-[(4-methylsulfonylphenyl)methoxy]pyrimidin-2-yl]piperazine-1-carboxylate
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|
C21H28N4O5S
|
1
|
| 1 |
IC50 = 543 nM
|
|
|
|
CP0025099
|
4-[[2-[(2R)-2-methyl-4-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)piperazin-1-yl]pyrimidin-5-yl]oxymethyl]pyridine-3-carbonitrile
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|
C21H24N8O2
|
1
|
| 1 |
IC50 = 568 nM
|
|
|
|
CP0508628
|
(2,2,3,3-tetrafluorocyclobutyl) (3R)-4-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]-3-methylpiperazine-1-carboxylate
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|
C21H20F4N6O3
|
1
|
| 1 |
IC50 = 694 nM
|
|
|
|
CP0478423
|
(2,2,3,3-tetrafluorocyclobutyl) 4-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]piperazine-1-carboxylate
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|
C20H18F4N6O3
|
1
|
| 1 |
IC50 = 758 nM
|
|
|
|
CP0091258
|
2,2,2-trifluoroethyl (3R)-4-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]-3-methylpiperazine-1-carboxylate
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|
C19H19F3N6O3
|
1
|
| 1 |
IC50 = 1827 nM
|
|
|
|
CP0515234
|
4-[[2-[4-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)piperazin-1-yl]pyrimidin-5-yl]oxymethyl]pyridine-3-carbonitrile
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|
C20H22N8O2
|
1
|
| 1 |
IC50 = 2716 nM
|
|
|
|
CP0055447
|
2,2,2-trifluoroethyl 4-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]piperazine-1-carboxylate
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|
C18H17F3N6O3
|
1
|
| 1 |
IC50 = 4985 nM
|
|
|
