Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
 Cell Line Info 
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT02259 , Neuropeptide Y receptor type 1
 Protein Info 
Gene Name NPY1R
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P25929
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053
 Cell Line Info 
 Protein ID: PT02259
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0463643
 Compound Info 
N-[[4-[[[1-(4-chlorophenyl)-3-hydroxypropan-2-yl]amino]methyl]cyclohexyl]methyl]naphthalene-1-sulfonamide
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C27H33ClN2O3S
  1
1
Ki = 3236 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0454764
 Compound Info 
N-[[4-[(1,2,3,4-tetrahydronaphthalen-2-ylmethylamino)methyl]cyclohexyl]methyl]naphthalene-1-sulfonamide
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C29H36N2O2S
  1
1
Ki = 3548 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0460756
 Compound Info 
N-[[4-[(1,2,3,4-tetrahydronaphthalen-2-ylmethylamino)methyl]cyclohexyl]methyl]naphthalene-2-sulfonamide
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C29H36N2O2S
  1
1
Ki = 5546 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528870
 Compound Info 
N-[6-(naphthalen-2-ylmethylamino)hexyl]naphthalene-2-sulfonamide
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C27H30N2O2S
  1
1
Ki = 7300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393872
 Compound Info 
N-[[4-[(naphthalen-2-ylmethylamino)methyl]cyclohexyl]methyl]-2-(trifluoromethyl)benzenesulfonamide
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C26H29F3N2O2S
  1
1
Ki = 12981 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463724
 Compound Info 
N-[[4-[(naphthalen-1-ylmethylamino)methyl]cyclohexyl]methyl]-2-(trifluoromethyl)benzenesulfonamide
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C26H29F3N2O2S
  1
1
Ki = 14454 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0041441
 Compound Info 
2-Nitro-N-(4-{[(1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-amino]-methyl}-cyclohexylmethyl)-benzenesulfonamide
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C25H33N3O4S
  1
1
Ki = 16032 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0461105
 Compound Info 
2-amino-N-[[4-[(1,2,3,4-tetrahydronaphthalen-2-ylmethylamino)methyl]cyclohexyl]methyl]benzenesulfonamide
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C25H35N3O2S
  1
1
Ki = 17179 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0383458
 Compound Info 
2-Nitro-N-(4-{[(quinolin-2-ylmethyl)-amino]-methyl}-cyclohexylmethyl)-benzenesulfonamide
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C24H28N4O4S
  1
1
Ki = 23714 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0438595
 Compound Info 
2-Nitro-N-(4-{[(quinolin-4-ylmethyl)-amino]-methyl}-cyclohexylmethyl)-benzenesulfonamide
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C24H28N4O4S
  1
1
Ki = 48697 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS