Brief Information of the Cell Line and Protein
Cell Line ID: CL000012 , Sf21
Synonyms
SF21
Sf-21
SF-21
IPLB-SF-21-AE
IPLB-Sf21-AE
IPLB-SF21-AE
IPLB-SF 21AE
IPLB-Sf21AE
IPLB-SF21AE
IPLB-SF-21
IPLB-Sf-21
IPLB-SF 21
IPLB-Sf21
IPLB-SF21
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0518
Protein ID: PT02178 , LIM domain kinase 1
Gene Name LIMK1
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P53667
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000012  Protein ID: PT02178
 
Compound ID Compound Name Compound Formula
CP0213232
4-[[5-[3-(2-chlorophenyl)pyridin-4-yl]-1,3-thiazol-2-yl]amino]phenol
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C20H14ClN3OS
 1
1
IC50 = 0.3 nM
   TI
   LI
   LO
   TS
CP0455940
N-[5-[3-(2-chloro-4-methylphenyl)pyridin-4-yl]-1,3-thiazol-2-yl]-2-methylpropanamide
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C19H18ClN3OS
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0384862
5-[3-(2-chlorophenyl)pyridin-4-yl]-N-phenyl-1,3-thiazol-2-amine
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C20H14ClN3S
 1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
CP0384865
N-[5-[3-(2-chlorophenyl)pyridin-4-yl]-1,3-thiazol-2-yl]-2-methylpropanamide
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C18H16ClN3OS
 1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
CP0431874
5-[3-(2-chlorophenyl)pyridin-4-yl]-N-[(1R)-1-phenylethyl]-1,3-thiazol-2-amine
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C22H18ClN3S
 1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CP0487240
5-[3-(2-chlorophenyl)pyridin-4-yl]-N-(2-methylpropyl)-1,3-thiazol-2-amine
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C18H18ClN3S
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0054626
N-[5-[3-[4-methoxy-2-(trifluoromethyl)phenyl]pyridin-4-yl]-1,3-thiazol-2-yl]-2-methylpropanamide
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C20H18F3N3O2S
 1
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
CP0388131
5-[3-[4-methoxy-2-(trifluoromethyl)phenyl]pyridin-4-yl]-N-propyl-1,3-thiazol-2-amine
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C19H18F3N3OS
 1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0394994
5-[3-(2-chlorophenyl)pyridin-4-yl]-N-propyl-1,3-thiazol-2-amine
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C17H16ClN3S
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0380087
N-[5-[3-(2-chlorophenyl)pyridin-4-yl]-1,3-thiazol-2-yl]acetamide
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C16H12ClN3OS
 1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0431875
N-propyl-5-[3-[2-(trifluoromethyl)phenyl]pyridin-4-yl]-1,3-thiazol-2-amine
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C18H16F3N3S
 1
1
IC50 = 37 nM
   TI
   LI
   LO
   TS
CP0417266
5-[3-(2-chlorophenyl)pyridin-4-yl]-N-[(1S)-1-phenylethyl]-1,3-thiazol-2-amine
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C22H18ClN3S
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0458946
5-[3-(2-methylphenyl)pyridin-4-yl]-N-propyl-1,3-thiazol-2-amine
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C18H19N3S
 1
1
IC50 = 82 nM
   TI
   LI
   LO
   TS
CP0431873
5-[3-(2-chlorophenyl)pyridin-4-yl]-N-ethyl-1,3-thiazol-2-amine
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C16H14ClN3S
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0406085
5-[3-(2-chlorophenyl)pyridin-4-yl]-1,3-thiazol-2-amine
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C14H10ClN3S
 1
1
IC50 = 270 nM
   TI
   LI
   LO
   TS
CP0471663
5-[2-(2-chlorophenyl)pyridin-3-yl]-N-propyl-1,3-thiazol-2-amine
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C17H16ClN3S
 1
1
IC50 = 327 nM
   TI
   LI
   LO
   TS
CP0508584
5-[3-(3-chlorophenyl)pyridin-4-yl]-N-propyl-1,3-thiazol-2-amine
   Show/Hide
C17H16ClN3S
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CP0546278
5-[4-(2-chlorophenyl)pyridin-3-yl]-N-propyl-1,3-thiazol-2-amine
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C17H16ClN3S
 1
1
IC50 = 574 nM
   TI
   LI
   LO
   TS
CP0417265
5-[3-(4-chlorophenyl)pyridin-4-yl]-N-propyl-1,3-thiazol-2-amine
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C17H16ClN3S
 1
1
IC50 = 620 nM
   TI
   LI
   LO
   TS
CP0467498
5-(3-phenylpyridin-4-yl)-N-propyl-1,3-thiazol-2-amine
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C17H17N3S
 1
1
IC50 = 850 nM
   TI
   LI
   LO
   TS
CP0409821
5-[3-(2-chlorophenyl)pyridin-4-yl]-N-methyl-N-propyl-1,3-thiazol-2-amine
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C18H18ClN3S
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0374774
5-[3-(2-propan-2-ylphenyl)pyridin-4-yl]-N-propyl-1,3-thiazol-2-amine
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C20H23N3S
 1
1
IC50 = 3300 nM
   TI
   LI
   LO
   TS
CP0176381
[4-amino-2-(prop-2-enylamino)-1,3-thiazol-5-yl]-(1,3-benzodioxol-5-yl)methanone
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C14H13N3O3S
 1
1
IC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0374775
N-propyl-5-pyridin-4-yl-1,3-thiazol-2-amine
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C11H13N3S
 1
1
IC50 = 19000 nM
   TI
   LI
   LO
   TS
CP0894055
5-(3-(2-chlorophenyl)pyridin-2-yl)-N-propylthiazol-2-amine
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C17H16ClN3S
 1
1
IC50 >= 30000 nM
   TI
   LI
   LO
   TS