| Compound ID |
Compound Name |
Compound Formula |
|
CP0436072
|
2-[2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]anilino]-5-methyl-11-methylsulfonylpyrimido[4,5-b][1,4]benzodiazepin-6-one
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|
C32H40N8O5S
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0024313
|
[2-amino-4-(trifluoromethoxy)phenyl]-[4-[7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl]methanone
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|
C25H28F3N7O2
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0521323
|
[4-(7-morpholin-4-ylpyrido[3,2-d]pyrimidin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
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|
C24H24F3N5O3
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0523267
|
[2-amino-4-(trifluoromethoxy)phenyl]-[4-(7-methoxyquinazolin-4-yl)piperidin-1-yl]methanone
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|
C22H21F3N4O3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0534714
|
[4-[7-(3-hydroxy-3-methylpyrrolidin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
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|
C25H26F3N5O3
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0575467
|
[4-[7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
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|
C25H27F3N6O2
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0436071
|
[3-amino-4-(trifluoromethoxy)phenyl]-[4-(7-methoxyquinazolin-4-yl)piperidin-1-yl]methanone
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|
C22H21F3N4O3
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0577138
|
[4-(7-methoxyquinazolin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
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|
C22H20F3N3O3
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0558071
|
[4-(7-methoxypyrido[3,2-d]pyrimidin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
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|
C21H19F3N4O3
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0555155
|
[4-[7-[3-(dimethylamino)pyrrolidin-1-yl]pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
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|
C26H29F3N6O2
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0523154
|
[4-(7-methoxyquinolin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
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|
C23H21F3N2O3
|
1
|
| 1 |
IC50 = 710 nM
|
|
|
|
CP0534712
|
[4-(6,7-dimethoxyquinazolin-4-yl)piperidin-1-yl]-(4-propan-2-yloxyphenyl)methanone
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|
C25H29N3O4
|
1
|
| 1 |
IC50 = 3750 nM
|
|
|
|
CP0469340
|
[4-(6-methoxyquinazolin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
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|
C22H20F3N3O3
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0561935
|
[4-(6,7-dimethoxyquinazolin-4-yl)piperidin-1-yl]-[6-(trifluoromethoxy)pyridin-3-yl]methanone
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|
C22H21F3N4O4
|
1
|
| 1 |
IC50 = 7640 nM
|
|
|
|
CP0552701
|
[4-(6-methoxypyrido[3,4-d]pyrimidin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
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|
C21H19F3N4O3
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0030297
|
[2-amino-4-(trifluoromethoxy)phenyl]-[4-[2-methyl-7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl]methanone
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|
C26H30F3N7O2
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0538081
|
[4-(6,7-dimethoxyquinazolin-4-yl)piperidin-1-yl]-(4-methylphenyl)methanone
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|
C23H25N3O3
|
1
|
| 1 |
IC50 = 11500 nM
|
|
|
|
CP0523155
|
[4-(6-methoxyisoquinolin-1-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
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|
C23H21F3N2O3
|
1
|
| 1 |
IC50 = 29000 nM
|
|
|
