Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
 Cell Line Info 
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01887 , Oxysterols receptor LXR-beta
 Protein Info 
Gene Name NR1H2
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P55055
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053
 Cell Line Info 
 Protein ID: PT01887
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0003740
 Compound Info 
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
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C17H12F9NO3S
  1
1
EC50 = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0006936
 Compound Info 
2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid
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C33H31ClF3NO3
  1
1
EC50 = 15 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440377
 Compound Info 
3-[4-(1-benzoyl-1H-indol-2-yl)phenyl]propanenitrile
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C24H18N2O
  1
1
EC50 = 42 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0394243
 Compound Info 
indole derivative, 5q
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C28H26F2N2O4S
  1
1
EC50 = 52 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0435641
 Compound Info 
indan derivative, 1
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C28H28N2O4S
  1
1
EC50 = 65 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0382151
 Compound Info 
indole derivative, 5b
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C28H27FN2O4S
  1
1
EC50 = 120 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440378
 Compound Info 
Boc-indole derivative, 26
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C22H24N2O3
  1
1
EC50 = 285 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0394242
 Compound Info 
indole derivative, 5t
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C29H27N3O5S2
  1
1
EC50 = 336 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440845
 Compound Info 
indole derivative, 5s
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C26H26N2O4S2
  1
1
EC50 = 363 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0532793
 Compound Info 
Boc-indole derivative, 22
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C22H22N2O2
  1
1
EC50 = 576 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0430040
 Compound Info 
3-(4-{1-[(tert-butoxy)carbonyl]-1H-indol-2-yl}phenyl)propanoic acid
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C22H23NO4
  1
1
EC50 = 4580 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS