Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01817 , Translocator protein
Gene Name TSPO
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P30536
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT01817
 
Compound ID Compound Name Compound Formula
CP0476561
2-[3-(4-methoxyphenyl)carbazol-9-yl]-N-[(3-methoxyphenyl)methyl]-N-methylacetamide
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C30H28N2O3
 4
1
Ki = 3.2 nM
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2
Ki = 6.6 nM
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3
Ki = 23.2 nM
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   LI
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4
Ki = 25.4 nM
   TI
   LI
   LO
   TS
CP0444593
(R)1-(2-Chloro-phenyl)-isoquinoline-3-carboxylic acid sec-butyl-methyl-amide
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C21H21ClN2O
 4
1
Ki = 13.6 nM
   TI
   LI
   LO
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2
Ki = 22.5 nM
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3
Ki = 26.7 nM
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4
Ki = 31.5 nM
   TI
   LI
   LO
   TS
CP0444586
2-carbazol-9-yl-N,N-diethylacetamide
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C18H20N2O
 2
1
Ki = 30.1 nM
   TI
   LI
   LO
   TS
2
Ki = 176.6 nM
   TI
   LI
   LO
   TS
CP0003888
1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoquinoline-3-carboxamide
   Show/Hide
C21H21ClN2O
 1
1
Ki = 36 nM
   TI
   LI
   LO
   TS
CP0444015
N-benzyl-2-carbazol-9-yl-N-methylacetamide
   Show/Hide
C22H20N2O
 2
1
Ki = 53 nM
   TI
   LI
   LO
   TS
2
Ki = 132 nM
   TI
   LI
   LO
   TS
CP0422965
N-benzyl-2-carbazol-9-yl-N-ethylacetamide
   Show/Hide
C23H22N2O
 2
1
Ki = 70 nM
   TI
   LI
   LO
   TS
2
Ki = 318.5 nM
   TI
   LI
   LO
   TS
CP0458218
2-carbazol-9-yl-N-ethyl-N-[(3-methoxyphenyl)methyl]acetamide
   Show/Hide
C24H24N2O2
 4
1
Ki = 96.1 nM
   TI
   LI
   LO
   TS
2
Ki = 100.4 nM
   TI
   LI
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3
Ki = 217.3 nM
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   LI
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4
Ki = 277 nM
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   LI
   LO
   TS
CP0443260
2-[2-(4'-Methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl]-N,N-diethylacetamide
   Show/Hide
C21H26N4O2
 1
1
Ki = 98.8 nM
   TI
   LI
   LO
   TS
CP0489660
2-carbazol-9-yl-N-ethyl-N-[(2-fluorophenyl)methyl]acetamide
   Show/Hide
C23H21FN2O
 2
1
Ki = 184.2 nM
   TI
   LI
   LO
   TS
2
Ki = 3123.2 nM
   TI
   LI
   LO
   TS
CP0444591
2-[3-(3-chlorophenyl)carbazol-9-yl]-N-[(3-methoxyphenyl)methyl]-N-methylacetamide
   Show/Hide
C29H25ClN2O2
 2
1
Ki = 200.7 nM
   TI
   LI
   LO
   TS
2
Ki = 639.4 nM
   TI
   LI
   LO
   TS
CP0422966
N-[(3-methoxyphenyl)methyl]-N-methyl-2-(3-phenylcarbazol-9-yl)acetamide
   Show/Hide
C29H26N2O2
 2
1
Ki = 208.4 nM
   TI
   LI
   LO
   TS
2
Ki = 231.2 nM
   TI
   LI
   LO
   TS
CP0444590
2-[3-(2-chlorophenyl)carbazol-9-yl]-N-[(3-methoxyphenyl)methyl]-N-methylacetamide
   Show/Hide
C29H25ClN2O2
 2
1
Ki = 214 nM
   TI
   LI
   LO
   TS
2
Ki = 231.3 nM
   TI
   LI
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CP0532026
N-[(2-acetamidophenyl)methyl]-2-carbazol-9-yl-N-ethylacetamide
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C25H25N3O2
 2
1
Ki = 243 nM
   TI
   LI
   LO
   TS
2
Ki > 10000 nM
   TI
   LI
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   TS
CP0575129
N-ethyl-2-[3-(4-methoxyphenyl)carbazol-9-yl]-N-[(3-methoxyphenyl)methyl]acetamide
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C31H30N2O3
 2
1
Ki = 369 nM
   TI
   LI
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   TS
2
Ki = 447.1 nM
   TI
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   TS
CP0444589
N-ethyl-N-[(3-methoxyphenyl)methyl]-2-(3-phenylcarbazol-9-yl)acetamide
   Show/Hide
C30H28N2O2
 2
1
Ki = 385.3 nM
   TI
   LI
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   TS
2
Ki = 418.2 nM
   TI
   LI
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   TS
CP0424198
2-(3-bromocarbazol-9-yl)-N-ethyl-N-[(3-methoxyphenyl)methyl]acetamide
   Show/Hide
C24H23BrN2O2
 2
1
Ki = 462.3 nM
   TI
   LI
   LO
   TS
2
Ki = 468.7 nM
   TI
   LI
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   TS
CP0576012
2-carbazol-9-yl-N-ethyl-N-[(3-fluorophenyl)methyl]acetamide
   Show/Hide
C23H21FN2O
 2
1
Ki = 562.5 nM
   TI
   LI
   LO
   TS
2
Ki > 10000 nM
   TI
   LI
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   TS
CP0443261
N,N-diethyl-2-[2-(4-methoxyphenyl)-4,6-dimethylindol-1-yl]acetamide
   Show/Hide
C23H28N2O2
 1
1
Ki = 652 nM
   TI
   LI
   LO
   TS
CP0476573
2-carbazol-9-yl-N-ethyl-N-[(4-fluorophenyl)methyl]acetamide
   Show/Hide
C23H21FN2O
 2
1
Ki = 693.8 nM
   TI
   LI
   LO
   TS
2
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0567446
N-(3,5-dimethylphenyl)-N-[(4-phenylmethoxyphenyl)methyl]acetamide
   Show/Hide
C24H25NO2
 1
1
Ki = 737.8 nM
   TI
   LI
   LO
   TS
CP0495666
5-(methanesulfonamido)-1-[(4-methoxyphenyl)methyl]-N-methyl-N-prop-2-ynylindole-2-carboxamide
   Show/Hide
C22H23N3O4S
 1
1
Ki = 760.9 nM
   TI
   LI
   LO
   TS
CP0508581
N,N-diethyl-2-[2-(4-methoxyphenyl)-4,6-dimethylbenzimidazol-1-yl]acetamide
   Show/Hide
C22H27N3O2
 1
1
Ki = 874.2 nM
   TI
   LI
   LO
   TS
CP0553593
1-[(6-methoxypyridin-3-yl)methyl]-N,5-dimethyl-N-prop-2-ynylindole-2-carboxamide
   Show/Hide
C21H21N3O2
 1
1
Ki = 982.7 nM
   TI
   LI
   LO
   TS
CP0570876
N-benzyl-N-(3,5-dimethylphenyl)acetamide
   Show/Hide
C17H19NO
 1
1
Ki = 1262 nM
   TI
   LI
   LO
   TS
CP0489659
2-carbazol-9-yl-N-ethyl-N-[(2-methoxyphenyl)methyl]acetamide
   Show/Hide
C24H24N2O2
 2
1
Ki = 1531.3 nM
   TI
   LI
   LO
   TS
2
Ki = 1551 nM
   TI
   LI
   LO
   TS
CP0476562
2-[3-(4-chlorophenyl)carbazol-9-yl]-N-[(3-methoxyphenyl)methyl]-N-methylacetamide
   Show/Hide
C29H25ClN2O2
 2
1
Ki = 1696 nM
   TI
   LI
   LO
   TS
2
Ki = 3555 nM
   TI
   LI
   LO
   TS
CP0511896
2-[3,5-dimethyl-N-[(4-phenylmethoxyphenyl)methyl]anilino]-N,N-diethylacetamide
   Show/Hide
C28H34N2O2
 1
1
Ki = 1770.7 nM
   TI
   LI
   LO
   TS
CP0565816
1-[(4-chlorophenyl)methyl]-N,N-diethylbenzimidazole-2-carboxamide
   Show/Hide
C19H20ClN3O
 1
1
Ki = 2570 nM
   TI
   LI
   LO
   TS
CP0570877
N-(3,5-dimethylphenyl)-N-[(4-methoxyphenyl)methyl]acetamide
   Show/Hide
C18H21NO2
 1
1
Ki = 2785 nM
   TI
   LI
   LO
   TS
CP0535136
5-acetamido-1-[(4-methoxyphenyl)methyl]-N-methyl-N-prop-2-ynylindole-2-carboxamide
   Show/Hide
C23H23N3O3
 1
1
Ki = 2861.4 nM
   TI
   LI
   LO
   TS
CP0565085
N-(3,5-dimethylphenyl)-N-[(4-propan-2-yloxyphenyl)methyl]acetamide
   Show/Hide
C20H25NO2
 1
1
Ki = 3147 nM
   TI
   LI
   LO
   TS
CP0574399
N-(3,5-dimethylphenyl)-N-[[4-(2-fluoroethoxy)phenyl]methyl]acetamide
   Show/Hide
C19H22FNO2
 1
1
Ki = 3933 nM
   TI
   LI
   LO
   TS
CP0495726
N,N-diethyl-2-[N-[(4-methoxyphenyl)methyl]-3,5-dimethylanilino]acetamide
   Show/Hide
C22H30N2O2
 1
1
Ki = 4211 nM
   TI
   LI
   LO
   TS
CP0563819
2-(N-benzyl-3,5-dimethylanilino)-N,N-diethylacetamide
   Show/Hide
C21H28N2O
 1
1
Ki = 4255 nM
   TI
   LI
   LO
   TS
CP0444584
2-carbazol-9-yl-N-ethyl-N-[(4-methoxyphenyl)methyl]acetamide
   Show/Hide
C24H24N2O2
 2
1
Ki = 4737.3 nM
   TI
   LI
   LO
   TS
2
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0444585
2-carbazol-9-yl-N,N-dimethylacetamide
   Show/Hide
C16H16N2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0444587
N-[(3-acetamidophenyl)methyl]-2-carbazol-9-yl-N-ethylacetamide
   Show/Hide
C25H25N3O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0444588
N-[(4-acetamidophenyl)methyl]-2-carbazol-9-yl-N-ethylacetamide
   Show/Hide
C25H25N3O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0444592
N-benzyl-2-carbazol-9-ylacetamide
   Show/Hide
C21H18N2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0458213
2-carbazol-9-yl-N-ethyl-N-[[3-(trifluoromethyl)phenyl]methyl]acetamide
   Show/Hide
C24H21F3N2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0458214
2-carbazol-9-yl-N-ethyl-N-[[4-(trifluoromethyl)phenyl]methyl]acetamide
   Show/Hide
C24H21F3N2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0458215
2-carbazol-9-yl-N-ethyl-N-(pyridin-4-ylmethyl)acetamide
   Show/Hide
C22H21N3O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0458216
2-(3-bromocarbazol-9-yl)-N-[(3-methoxyphenyl)methyl]-N-methylacetamide
   Show/Hide
C23H21BrN2O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0519376
2-carbazol-9-yl-N-ethyl-N-(pyridin-3-ylmethyl)acetamide
   Show/Hide
C22H21N3O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0532025
2-carbazol-9-yl-N-ethyl-N-[[2-(trifluoromethyl)phenyl]methyl]acetamide
   Show/Hide
C24H21F3N2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0535609
2-carbazol-9-yl-N-ethyl-N-(pyridin-2-ylmethyl)acetamide
   Show/Hide
C22H21N3O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0495723
N,N-diethyl-1-[(6-methoxypyridin-3-yl)methyl]benzimidazole-2-carboxamide
   Show/Hide
C19H22N4O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0495724
N,N-diethyl-5-methyl-1-[(4-phenylmethoxyphenyl)methyl]indole-2-carboxamide
   Show/Hide
C28H30N2O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0559987
1-[(4-methoxyphenyl)methyl]-N-methyl-N-prop-2-ynylbenzimidazole-2-carboxamide
   Show/Hide
C20H19N3O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0560249
1-benzyl-N,N-diethylbenzimidazole-2-carboxamide
   Show/Hide
C19H21N3O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0560250
N,N-diethyl-1-[(4-hydroxyphenyl)methyl]-5-methylindole-2-carboxamide
   Show/Hide
C21H24N2O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0560251
N,N-diethyl-5-methyl-1-(2H-triazol-4-ylmethyl)indole-2-carboxamide
   Show/Hide
C17H21N5O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0560281
N,N-diethyl-2-[N-[[4-(2-fluoroethoxy)phenyl]methyl]-3,5-dimethylanilino]acetamide
   Show/Hide
C23H31FN2O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0563818
N-benzyl-1-[(4-chlorophenyl)methyl]-N-methylbenzimidazole-2-carboxamide
   Show/Hide
C23H20ClN3O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0567444
N,N-diethyl-1-[(4-methoxyphenyl)methyl]benzimidazole-2-carboxamide
   Show/Hide
C20H23N3O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0567445
1-[(4-chlorophenyl)methyl]-N-methyl-N-prop-2-ynylbenzimidazole-2-carboxamide
   Show/Hide
C19H16ClN3O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0578984
2-[3,5-dimethyl-N-[(4-propan-2-yloxyphenyl)methyl]anilino]-N,N-diethylacetamide
   Show/Hide
C24H34N2O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS