Brief Information of the Cell Line and Protein
Cell Line ID: CL000018 , HL-60
Synonyms
HL 60
HL.60
HL60
Human Leukemia-60
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0002
Protein ID: PT01801 , Leukotriene B4 receptor 1
Gene Name LTB4R
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q15722
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000018  Protein ID: PT01801
 
Compound ID Compound Name Compound Formula
CP0068053
4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-pyridin-4-yl-phenoxy)-hexyl]-phenoxy}-butyric acid
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C35H38N2O6
 1
1
IC50 = 0.07 nM
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CP0539445
4-{2-(2-Carboxy-ethyl)-3-[6-(3'-fluoro-5-pyridin-4-yl-biphenyl-3-yloxy)-hexyl]-phenoxy}-butyric acid
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C36H38FNO6
 1
1
IC50 = 0.18 nM
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CP0402256
4-{2-(2-Carboxy-ethyl)-3-[6-(3-pyridin-4-yl-5-thiophen-3-yl-phenoxy)-hexyl]-phenoxy}-butyric acid
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C34H37NO6S
 1
1
IC50 = 0.2 nM
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CP0046202
4-{2-(2-Carboxyethyl)-3-[6-([1,1',3,1'']terphenyl-5'-yloxy)-hexyl]phenoxy}butyric Acid
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C37H40O6
 1
1
IC50 = 0.21 nM
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CP0489438
4-{3-[6-(3-Benzo[1,3]dioxol-5-yl-5-pyridin-4-yl-phenoxy)-hexyl]-2-(2-carboxy-ethyl)-phenoxy}-butyric acid
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C37H39NO8
 1
1
IC50 = 0.22 nM
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CP0376658
4-{2-(2-Carboxyethyl)-3-[6-(5-thiophen-3-ylbiphenyl-3-yloxy)-hexyl]phenoxy}butyric Acid
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C35H38O6S
 1
1
IC50 = 0.36 nM
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CP0376659
4-{3-[6-(3-Benzo[1,3]dioxol-5-yl-5-pyrimidin-5-yl-phenoxy)-hexyl]-2-(2-carboxy-ethyl)-phenoxy}-butyric acid
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C36H38N2O8
 1
1
IC50 = 0.38 nM
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CP0376660
4-{2-(2-Carboxy-ethyl)-3-[6-(3-pyrimidin-5-yl-5-thiophen-3-yl-phenoxy)-hexyl]-phenoxy}-butyric acid
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C33H36N2O6S
 1
1
IC50 = 0.39 nM
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CP0093691
4-{3-[6-(3-5-Benzo[1,3]dioxolyl-5-thiophen-3-ylphenoxy)hexyl]-2-(2-carboxyethyl)phenoxy}butyric Acid
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C36H38O8S
 1
1
IC50 = 0.44 nM
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CP0093685
4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-yloxy)hexyl)phenoxy)butanoic acid
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C36H39NO6
 1
1
IC50 = 0.48 nM
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CP0489439
4-(2-(2-Carboxy-ethyl)-3-{6-[3-(2-chloro-pyridin-4-yl-5-thiophen-3-yl-phenoxy)-hexyl]-phenoxy}-butyric acid
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C34H36ClNO6S
 1
1
IC50 = 0.57 nM
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CP0507934
4-[3-[6-(5-Benzo[1,3]dioxol-5-yl-biphenyl-3-yloxy)-hexyl]-2-(2-carboxy-ethyl)-phenoxy]-butyric acid
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C38H40O8
 1
1
IC50 = 0.58 nM
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CP0514834
4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-thiophen-3-yl-phenoxy)-hexyl]-phenoxy}-butyric acid
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C33H36O6S2
 1
1
IC50 = 0.58 nM
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CP0224886
4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-2'-fluorobiphenyl-3-yloxy)hexyl)-2-(2-carboxyethyl)phenoxy)butanoic acid
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C38H39FO8
 1
1
IC50 = 0.61 nM
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CP0068015
4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-3'-fluorobiphenyl-3-yloxy)hexyl)-2-(2-carboxyethyl)phenoxy)butanoic acid
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C38H39FO8
 1
1
IC50 = 1.19 nM
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CP0430044
4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-4'-methoxybiphenyl-3-yloxy)hexyl)-2-(2-carboxyethyl)phenoxy)butanoic acid
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C39H42O9
 1
1
IC50 = 3.27 nM
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CP0400640
4-{2-(2-Carboxyethyl)-3-[6-(3,5-dipyrimidin-5-ylphenoxy)hexyl]-phenoxy}butyric Acid
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C35H38N2O6
 1
1
IC50 = 5.35 nM
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CP0479967
4-[3-[6-(3,5-Bis-benzo[1,3]dioxol-5-yl-phenoxy)-hexyl]-2-(2-carboxy-ethyl)-phenoxy]-butyric acid
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C39H40O10
 1
1
IC50 = 5.39 nM
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CP0452179
4-{2-(2-Carboxy-ethyl)-3-[6-(4,4''-difluoro-[1.1':3',1'']terphenyl-5'-yloxy)-hexyl]-phenoxy}-butyric acid
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C37H38F2O6
 1
1
IC50 = 8.5 nM
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CP0489469
4-(2-(2-Carboxy-ethyl)-3-{6-[3'-fluoro-5-(1H-indol-5-yl)-biphenyl-3-yloxy]-hexyl}-phenoxy)-butyric acid
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C39H40FNO6
 1
1
IC50 = 13.98 nM
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CP0400641
4-{2-(2-Carboxy-ethyl)-3-[6-(4,4''-dimethoxy-[1.1':3',1'']terphenyl-5'-yloxy)-hexyl]-phenoxy}-butyric acid
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C39H44O8
 1
1
IC50 = 31.1 nM
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CP0402254
4-(2-(2-carboxyethyl)-3-(6-(5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4'-fluorobiphenyl-3-yloxy)hexyl)phenoxy)butanoic acid
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C39H41FO8
 1
1
IC50 = 60.2 nM
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CP0417985
4-[3-{6-[3,5-Bis-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-phenoxy]-hexyl}-2-(2-carboxy-ethyl)-phenoxy]-butyric acid
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C41H44O10
 1
1
IC50 = 139.7 nM
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