All Bioactivity

Brief Information of the Cell Line and Protein

Cell Line ID: CL000101 , L-M(TK-)

Cell Line Info

Synonyms	L-M[TK-] LM TK negative L-M (TK-) L M (TK-) LM(TK-) LM(tk-) LM-TK- LMTK- L cells (TK-) L(TK-) L(tk-)
Category	Spontaneously immortalized cell line
Organism	Mus musculus (Mouse)
Cellosaurus ID	CVCL_4536

Protein ID: PT01795 , Neuropeptide Y receptor type 5

Protein Info

Gene Name	NPY5R
Organism	Homo sapiens, Human
Protein Classification	Membrane receptor
Uniprot ID	Q15761

Table of Molecular Bioactivities Related to the Cell Line and Protein

Cell Line ID: CL000101

Cell Line Info

Protein ID: PT01795

Protein Info

Compound ID	Compound Name	Compound Formula
CP0465078 Compound Info	N-(3,4-dichlorophenyl)-1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C20H21Cl2N3O3S	1
1	IC50 = 0.2 nM Bioactivity Info	TI LI LO TS
CP0369979 Compound Info	1-(Methylsulfonyl)-N-(5-phenylpyrimidin-2-yl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C24H25N5O3S	1
1	IC50 = 0.57 nM Bioactivity Info	TI LI LO TS
CP0498823 Compound Info	2-N-[4-(ethylsulfonylmethyl)phenyl]-4-N-phenylquinazoline-2,4-diamine Show/Hide	C23H22N4O2S	1
1	IC50 = 0.6 nM Bioactivity Info	TI LI LO TS
CP0497098 Compound Info	3-oxo-N-(5-phenylpyrimidin-2-yl)spiro[2-benzofuran-1,4'-cyclohexane]-1'-carboxamide Show/Hide	C24H21N3O3	1
1	IC50 = 0.64 nM Bioactivity Info	TI LI LO TS
CP0036924 Compound Info	N-[3-(4-chlorophenyl)-1,2-oxazol-5-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C22H18ClN3O4	1
1	IC50 = 0.69 nM Bioactivity Info	TI LI LO TS
CP0165638 Compound Info	1-(Methylsulfonyl)-N-(6-phenylpyridin-3-yl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C25H26N4O3S	1
1	IC50 = 0.82 nM Bioactivity Info	TI LI LO TS
CP0417998 Compound Info	N-[3-(2-chlorophenyl)-1,2-oxazol-5-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C22H18ClN3O4	1
1	IC50 = 0.83 nM Bioactivity Info	TI LI LO TS
CP0457503 Compound Info	3-oxo-N-(3-phenylisoxazol-5-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C22H19N3O4	1
1	IC50 = 0.84 nM Bioactivity Info	TI LI LO TS
CP0498324 Compound Info	3-oxo-N-(5-(3-(trifluoromethyl)phenyl)pyrimidin-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C24H19F3N4O3	1
1	IC50 = 0.85 nM Bioactivity Info	TI LI LO TS
CP0398654 Compound Info	1-methylsulfonyl-N-(4-phenylphenyl)spiro[2H-indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C26H27N3O3S	1
1	IC50 = 0.85 nM Bioactivity Info	TI LI LO TS
CP0277347 Compound Info	1-(Methylsulfonyl)-N-(2-phenylpyrimidin-5-yl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C24H25N5O3S	1
1	IC50 = 0.86 nM Bioactivity Info	TI LI LO TS
CP0463961 Compound Info	1-[4-[(4-anilinoquinazolin-2-yl)amino]phenyl]-N,N-dimethylmethanesulfonamide Show/Hide	C23H23N5O2S	1
1	IC50 = 0.9 nM Bioactivity Info	TI LI LO TS
CP0417999 Compound Info	N-[5-(3-chlorophenyl)pyrimidin-2-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C23H19ClN4O3	1
1	IC50 = 0.91 nM Bioactivity Info	TI LI LO TS
CP0315843 Compound Info	1-(Methylsulfonyl)-N-(5-phenylpyridin-2-yl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C25H26N4O3S	1
1	IC50 = 0.96 nM Bioactivity Info	TI LI LO TS
CP0151121 Compound Info	1-(Methylsulfonyl)-N-(5-phenylpyrazin-2-yl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C24H25N5O3S	1
1	IC50 = 0.97 nM Bioactivity Info	TI LI LO TS
CP0374385 Compound Info	N-[5-(2-fluorophenyl)pyrimidin-2-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 0.99 nM Bioactivity Info	TI LI LO TS
CP0400858 Compound Info	N-[3-(3-chlorophenyl)-1,2-oxazol-5-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C22H18ClN3O4	1
1	IC50 = 1 nM Bioactivity Info	TI LI LO TS
CP0374387 Compound Info	N-[5-(2-methoxyphenyl)pyrimidin-2-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C24H22N4O4	1
1	IC50 = 1.1 nM Bioactivity Info	TI LI LO TS
CP0418000 Compound Info	N-[5-(2-chlorophenyl)pyrimidin-2-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C23H19ClN4O3	1
1	IC50 = 1.1 nM Bioactivity Info	TI LI LO TS
CP0472136 Compound Info	N-[5-(3-fluorophenyl)pyrimidin-2-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 1.1 nM Bioactivity Info	TI LI LO TS
CP0439725 Compound Info	3-oxo-N-(5-phenyl-1,2,4-thiadiazol-3-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C21H18N4O3S	1
1	IC50 = 1.2 nM Bioactivity Info	TI LI LO TS
CP0127404 Compound Info	1'-(5-chloro-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H16ClN3O2	2
1	IC50 = 1.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 6.6 nM Bioactivity Info	TI LI LO TS
CP0494755 Compound Info	N-(4-butylphenyl)-1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C24H31N3O3S	1
1	IC50 = 1.2 nM Bioactivity Info	TI LI LO TS
CP0506545 Compound Info	3-oxo-N-(5-(2-(trifluoromethyl)phenyl)pyrimidin-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C24H19F3N4O3	1
1	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
CP0398655 Compound Info	1-methylsulfonyl-N-(3-phenylphenyl)spiro[2H-indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C26H27N3O3S	1
1	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
CP0197859 Compound Info	3-oxo-N-(5-phenylpyrimidin-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C23H20N4O3	1
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
CP0169161 Compound Info	1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H15Cl2N3O2	2
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.6 nM Bioactivity Info	TI LI LO TS
CP0553188 Compound Info	N-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]-4-[2-(methanesulfonamido)phenyl]piperazine-1-carboxamide Show/Hide	C21H23ClN6O3S	1
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
CP0269315 Compound Info	methyl 2-(3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-yl)-3H-benzimidazole-5-carboxylate Show/Hide	C21H19N3O4	2
1	IC50 = 1.5 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.7 nM Bioactivity Info	TI LI LO TS
CP0465093 Compound Info	1-methylsulfonyl-N-(4-phenylphenyl)spiro[2H-indole-3,4'-cyclohexane]-1'-carboxamide Show/Hide	C27H28N2O3S	1
1	IC50 = 1.5 nM Bioactivity Info	TI LI LO TS
CP0089678 Compound Info	N-[5-(2-fluorophenyl)pyrimidin-2-yl]-3'-oxospiro[cyclohexane-4,1'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 1.5 nM Bioactivity Info	TI LI LO TS
CP0469883 Compound Info	N-[5-(3-fluorophenyl)pyrimidin-2-yl]-3'-oxospiro[cyclohexane-4,1'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 1.5 nM Bioactivity Info	TI LI LO TS
CP0397056 Compound Info	3-oxo-N-(5-phenylpyrazin-2-yl)-3,4-dihydro-2H-spiro[isoquinoline-1,4'-piperidine]-1'-carboxamide Show/Hide	C24H23N5O2	1
1	IC50 = 1.7 nM Bioactivity Info	TI LI LO TS
CP0541903 Compound Info	4'-[6-(4-fluorophenyl)-1H-benzimidazol-2-yl]spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C26H21FN2O2	1
1	IC50 = 1.7 nM Bioactivity Info	TI LI LO TS
CP0400859 Compound Info	3-oxo-N-(5-phenylthiazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C22H19N3O3S	1
1	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0503987 Compound Info	N-[5-(3-methoxyphenyl)pyrimidin-2-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C24H22N4O4	1
1	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0169152 Compound Info	1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C25H21N3O2	2
1	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
CP0524171 Compound Info	1'-(5-isobutyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C23H25N3O2	1
1	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0317637 Compound Info	1'-oxo-N-(5-phenylpyrimidin-2-yl)spiro[cyclohexane-4,3'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C23H20N4O3	1
1	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0381130 Compound Info	N-[5-[3-(fluoromethyl)phenyl]pyrimidin-2-yl]-1'-oxospiro[cyclohexane-4,3'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C24H21FN4O3	1
1	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0447557 Compound Info	N-[5-[3-(fluoromethoxy)phenyl]pyrimidin-2-yl]-3'-oxospiro[cyclohexane-4,1'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C24H21FN4O4	1
1	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0497100 Compound Info	N-[5-(3-fluorophenyl)pyrimidin-2-yl]-1'-oxospiro[cyclohexane-4,3'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0500605 Compound Info	N-[5-(2-fluorophenyl)pyrimidin-2-yl]-1'-oxospiro[cyclohexane-4,3'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0457504 Compound Info	3-oxo-N-(3-phenyl-1H-pyrazol-5-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C22H20N4O3	1
1	IC50 = 1.9 nM Bioactivity Info	TI LI LO TS
CP0447558 Compound Info	N-[5-[3-(fluoromethoxy)phenyl]pyrimidin-2-yl]-1'-oxospiro[cyclohexane-4,3'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C24H21FN4O4	1
1	IC50 = 1.9 nM Bioactivity Info	TI LI LO TS
CP0525466 Compound Info	N-[[4-[(4-anilinoquinazolin-2-yl)amino]cyclohexyl]methyl]methanesulfonamide Show/Hide	C22H27N5O2S	1
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0377445 Compound Info	ethyl 2-(3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-yl)-3H-benzimidazole-5-carboxylate Show/Hide	C22H21N3O4	1
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0492688 Compound Info	N-(4-acetylphenyl)-1-sulfamoylspiro[2H-indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C21H24N4O4S	1
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0341629 Compound Info	3'-oxo-N-(5-phenylpyrimidin-2-yl)spiro[cyclohexane-4,1'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C23H20N4O3	1
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0469888 Compound Info	N-[5-[2-(fluoromethyl)phenyl]pyrimidin-2-yl]-1'-oxospiro[cyclohexane-4,3'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C24H21FN4O3	1
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0515863 Compound Info	CHEMBL489608 Show/Hide	C23H17F3N4O3	1
1	IC50 = 2.1 nM Bioactivity Info	TI LI LO TS
CP0315865 Compound Info	1-(Methylsulfonyl)-N-[4-(pyridin-3-yl)phenyl]-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C25H26N4O3S	1
1	IC50 = 2.1 nM Bioactivity Info	TI LI LO TS
CP0371162 Compound Info	7'-oxo-N-(5-phenylpyrimidin-2-yl)spiro[cyclohexane-4,5'-furo[3,4-b]pyridine]-1-carboxamide Show/Hide	C23H20N4O3	1
1	IC50 = 2.1 nM Bioactivity Info	TI LI LO TS
CP0457505 Compound Info	3-oxo-N-(2-phenylpyrimidin-5-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C23H20N4O3	1
1	IC50 = 2.2 nM Bioactivity Info	TI LI LO TS
CP0460325 Compound Info	1'-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one Show/Hide	C20H15F2N3O4	1
1	IC50 = 2.2 nM Bioactivity Info	TI LI LO TS
CP0541904 Compound Info	CHEMBL490824 Show/Hide	C26H21ClN2O2	1
1	IC50 = 2.2 nM Bioactivity Info	TI LI LO TS
CP0541905 Compound Info	methyl 6-chloro-2-(3-oxospiro[2-benzofuran-1,4'-cyclohexane]-1'-yl)-1H-benzimidazole-5-carboxylate Show/Hide	C22H19ClN2O4	1
1	IC50 = 2.2 nM Bioactivity Info	TI LI LO TS
CP0469884 Compound Info	N-[5-[2-(fluoromethoxy)phenyl]pyrimidin-2-yl]-3'-oxospiro[cyclohexane-4,1'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C24H21FN4O4	1
1	IC50 = 2.2 nM Bioactivity Info	TI LI LO TS
CP0473825 Compound Info	N-[5-(3-fluorophenyl)pyrimidin-2-yl]-7'-oxospiro[cyclohexane-4,5'-furo[3,4-b]pyridine]-1-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 2.2 nM Bioactivity Info	TI LI LO TS
CP0497099 Compound Info	N-[5-(4-fluorophenyl)pyrimidin-2-yl]-3'-oxospiro[cyclohexane-4,1'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 2.2 nM Bioactivity Info	TI LI LO TS
CP0439726 Compound Info	3-oxo-N-(1-phenyl-1H-pyrazol-4-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C22H20N4O3	1
1	IC50 = 2.3 nM Bioactivity Info	TI LI LO TS
CP0541902 Compound Info	4'-(6-phenyl-1H-benzimidazol-2-yl)spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C26H22N2O2	1
1	IC50 = 2.3 nM Bioactivity Info	TI LI LO TS
CP0455297 Compound Info	N-[5-[3-(fluoromethyl)phenyl]pyrimidin-2-yl]-7'-oxospiro[cyclohexane-4,5'-furo[3,4-b]pyridine]-1-carboxamide Show/Hide	C24H21FN4O3	1
1	IC50 = 2.3 nM Bioactivity Info	TI LI LO TS
CP0128739 Compound Info	3-oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C23H20N4O3	3
1	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 6.1 nM Bioactivity Info	TI LI LO TS
3	Ki = 2.4 nM Bioactivity Info	TI LI LO TS
CP0443334 Compound Info	N-[5-(4-fluorophenyl)pyrimidin-2-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
CP0515860 Compound Info	CHEMBL491230 Show/Hide	C27H22N2O3	1
1	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
CP0525966 Compound Info	4'-(6-pyridin-2-yl-1H-benzimidazol-2-yl)spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C25H21N3O2	1
1	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
CP0503032 Compound Info	4'-[5-chloro-6-(trifluoromethyl)-1H-benzimidazol-2-yl]spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C21H16ClF3N2O2	1
1	IC50 = 2.6 nM Bioactivity Info	TI LI LO TS
CP0531204 Compound Info	N-[5-[2-(fluoromethoxy)phenyl]pyrimidin-2-yl]-1'-oxospiro[cyclohexane-4,3'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C24H21FN4O4	1
1	IC50 = 2.6 nM Bioactivity Info	TI LI LO TS
CP0289007 Compound Info	N-[[4-[(4-aminoquinazolin-2-yl)amino]cyclohexyl]methyl]naphthalene-1-sulfonamide Show/Hide	C25H27N5O2S	1
1	IC50 = 2.7 nM Bioactivity Info	TI LI LO TS
CP0500606 Compound Info	N-[5-(4-fluorophenyl)pyrimidin-2-yl]-1'-oxospiro[cyclohexane-4,3'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 2.7 nM Bioactivity Info	TI LI LO TS
CP0039984 Compound Info	CGP 71683 Show/Hide	C26H29N5O2S	1
1	IC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0505333 Compound Info	N-[[4-[2-[(4-aminoquinazolin-2-yl)amino]ethyl]cyclohexyl]methyl]naphthalene-1-sulfonamide Show/Hide	C27H31N5O2S	1
1	IC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0514678 Compound Info	3-oxo-N-(1-phenyl-1H-pyrazol-3-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C22H20N4O3	1
1	IC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0341631 Compound Info	5'-oxo-N-(5-phenylpyrimidin-2-yl)spiro[cyclohexane-4,7'-furo[3,4-b]pyridine]-1-carboxamide Show/Hide	C23H20N4O3	1
1	IC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0165636 Compound Info	1-(Methylsulfonyl)-N-[4-(pyridin-2-yl)phenyl]-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C25H26N4O3S	1
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0165637 Compound Info	1-(Methylsulfonyl)-N-(6-phenylpyridazin-3-yl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C24H25N5O3S	1
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0464270 Compound Info	N-(4-phenoxyphenyl)-1-sulfamoylspiro[2H-indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C25H26N4O4S	1
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0502783 Compound Info	N-[5-(2-fluorophenyl)pyrimidin-2-yl]-7'-oxospiro[cyclohexane-4,5'-furo[3,4-b]pyridine]-1-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0540419 Compound Info	4'-(6-pyridin-3-yl-1H-benzimidazol-2-yl)spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C25H21N3O2	1
1	IC50 = 3.1 nM Bioactivity Info	TI LI LO TS
CP0473886 Compound Info	N-[5-[3-(fluoromethoxy)phenyl]pyrimidin-2-yl]-7'-oxospiro[cyclohexane-4,5'-furo[3,4-b]pyridine]-1-carboxamide Show/Hide	C24H21FN4O4	1
1	IC50 = 3.1 nM Bioactivity Info	TI LI LO TS
CP0252962 Compound Info	4'-[6-(5-methyl-1,3,4-oxadiazol-2-yl)-1H-benzimidazol-2-yl]spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C23H20N4O3	2
1	IC50 = 3.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5.5 nM Bioactivity Info	TI LI LO TS
CP0472137 Compound Info	3-oxo-N-(5-phenyl-1,3,4-thiadiazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C21H18N4O3S	1
1	IC50 = 3.4 nM Bioactivity Info	TI LI LO TS
CP0397057 Compound Info	3-oxo-N-(1-phenyl-1H-imidazol-4-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C22H20N4O3	1
1	IC50 = 3.5 nM Bioactivity Info	TI LI LO TS
CP0262513 Compound Info	1'-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C20H16F3N3O2	2
1	IC50 = 3.5 nM Bioactivity Info	TI LI LO TS
2	IC50 = 6400 nM Bioactivity Info	TI LI LO TS
CP0397058 Compound Info	3-oxo-N-(5-phenylpyrazin-2-yl)spiro[isoindoline-1,4'-piperidine]-1'-carboxamide Show/Hide	C23H21N5O2	1
1	IC50 = 3.7 nM Bioactivity Info	TI LI LO TS
CP0523236 Compound Info	N-[5-(4-chlorophenyl)pyrimidin-2-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C23H19ClN4O3	1
1	IC50 = 3.9 nM Bioactivity Info	TI LI LO TS
CP0404102 Compound Info	2-N-[4-(diethylamino)phenyl]-4-N-phenylquinazoline-2,4-diamine Show/Hide	C24H25N5	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0506644 Compound Info	4-Methyl-N-[4-(4-phenylamino-quinazolin-2-ylamino)-cyclohexylmethyl]-benzenesulfonamide Show/Hide	C28H31N5O2S	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0465094 Compound Info	N-(3,4-dichlorophenyl)-1-sulfamoylspiro[2H-indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C19H20Cl2N4O3S	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0166490 Compound Info	1-(Methylsulfonyl)-N-[4-(pyridin-4-yl)phenyl]-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C25H26N4O3S	1
1	IC50 = 4.1 nM Bioactivity Info	TI LI LO TS
CP0522723 Compound Info	methyl 4-chloro-2-(3-oxospiro[2-benzofuran-1,4'-cyclohexane]-1'-yl)-1H-benzimidazole-5-carboxylate Show/Hide	C22H19ClN2O4	1
1	IC50 = 4.5 nM Bioactivity Info	TI LI LO TS
CP0531203 Compound Info	N-[5-[2-(fluoromethoxy)phenyl]pyrimidin-2-yl]-7'-oxospiro[cyclohexane-4,5'-furo[3,4-b]pyridine]-1-carboxamide Show/Hide	C24H21FN4O4	1
1	IC50 = 4.5 nM Bioactivity Info	TI LI LO TS
CP0460324 Compound Info	1'-(5,6-difluoro-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H15F2N3O2	1
1	IC50 = 4.8 nM Bioactivity Info	TI LI LO TS
CP0489742 Compound Info	N-(2-chlorophenyl)-1-sulfamoylspiro[2H-indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C19H21ClN4O3S	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0247192 Compound Info	4'-[6-(5-methyl-1,2,4-oxadiazol-3-yl)-1H-benzimidazol-2-yl]spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C23H20N4O3	2
1	IC50 = 5.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0295791 Compound Info	3-oxo-N-(5-phenylpyrazin-2-yl)spiro[isochroman-1,4'-piperidine]-1'-carboxamide Show/Hide	C24H22N4O3	1
1	IC50 = 5.7 nM Bioactivity Info	TI LI LO TS
CP0517458 Compound Info	1'-(4,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H15Cl2N3O2	1
1	IC50 = 5.7 nM Bioactivity Info	TI LI LO TS
CP0247191 Compound Info	4'-[6-(2-methyltetrazol-5-yl)-1H-benzimidazol-2-yl]spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C22H20N6O2	2
1	IC50 = 5.9 nM Bioactivity Info	TI LI LO TS
2	IC50 = 7.2 nM Bioactivity Info	TI LI LO TS
CP0512320 Compound Info	Acetic acid 4-(4-phenylamino-quinazolin-2-ylamino)-cyclohexyl ester Show/Hide	C22H24N4O2	1
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0374388 Compound Info	3-oxo-N-(6-phenylpyridazin-3-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C23H20N4O3	1
1	IC50 = 6.1 nM Bioactivity Info	TI LI LO TS
CP0422661 Compound Info	1'-(5-chloro-6-fluoro-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H15ClFN3O2	1
1	IC50 = 6.7 nM Bioactivity Info	TI LI LO TS
CP0095353 Compound Info	1-(Methylsulfonyl)-N-(2-phenylpyrimidin-4-yl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C24H25N5O3S	1
1	IC50 = 7.5 nM Bioactivity Info	TI LI LO TS
CP0405503 Compound Info	N-[5-(4-fluorophenyl)pyrimidin-2-yl]-7'-oxospiro[cyclohexane-4,5'-furo[3,4-b]pyridine]-1-carboxamide Show/Hide	C23H19FN4O3	1
1	IC50 = 7.5 nM Bioactivity Info	TI LI LO TS
CP0503033 Compound Info	methyl 2-(3-oxospiro[2-benzofuran-1,4'-cyclohexane]-1'-yl)-3H-benzimidazole-5-carboxylate Show/Hide	C22H20N2O4	1
1	IC50 = 7.7 nM Bioactivity Info	TI LI LO TS
CP0496658 Compound Info	3-oxo-N-(4-phenylthiazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C22H19N3O3S	1
1	IC50 = 7.9 nM Bioactivity Info	TI LI LO TS
CP0514764 Compound Info	4'-(5,6-dichloro-1H-benzimidazol-2-yl)spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C20H16Cl2N2O2	1
1	IC50 = 8 nM Bioactivity Info	TI LI LO TS
CP0291503 Compound Info	1-(Difluoromethyl)-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one Show/Hide	C21H16F4N4O	2
1	IC50 = 8.7 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.8 nM Bioactivity Info	TI LI LO TS
CP0457516 Compound Info	1'-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C21H21N3O2	1
1	IC50 = 9.2 nM Bioactivity Info	TI LI LO TS
CP0490173 Compound Info	1'-(5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one Show/Hide	C20H17N3O4	1
1	IC50 = 9.3 nM Bioactivity Info	TI LI LO TS
CP0129940 Compound Info	1-(Methylsulfonyl)-N-(4-phenylpyrimidin-2-yl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C24H25N5O3S	1
1	IC50 = 9.8 nM Bioactivity Info	TI LI LO TS
CP0488149 Compound Info	1'-(5-bromo-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H16BrN3O2	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0489721 Compound Info	1'-(5-nitro-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H16N4O4	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0472138 Compound Info	N-[5-(4-methoxyphenyl)pyrimidin-2-yl]-3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C24H22N4O4	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0522871 Compound Info	4'-[6-(1,3,4-oxadiazol-2-yl)-1H-benzimidazol-2-yl]spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C22H18N4O3	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0474981 Compound Info	5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-1-methoxypyridin-2(1H)-one Show/Hide	C21H18F2N4O2	2
1	IC50 = 15.7 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.8 nM Bioactivity Info	TI LI LO TS
CP0528766 Compound Info	N-[[4-[[(4-aminoquinazolin-2-yl)-methylamino]methyl]cyclohexyl]methyl]naphthalene-1-sulfonamide Show/Hide	C27H31N5O2S	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0465784 Compound Info	1'-(4-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C25H21N3O2	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0554477 Compound Info	2-(3-oxo-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)-1H-benzo[d]imidazole-5-carbonitrile Show/Hide	C20H16N4O2	1
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0503008 Compound Info	2-N-(4-cyclohexylphenyl)-4-N-phenylquinazoline-2,4-diamine Show/Hide	C26H26N4	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0472139 Compound Info	3-oxo-N-(5-(4-(trifluoromethyl)phenyl)pyrimidin-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide Show/Hide	C24H19F3N4O3	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0532053 Compound Info	N-methyl-2-(3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-yl)-3H-benzimidazole-5-carboxamide Show/Hide	C21H20N4O3	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0541901 Compound Info	CHEMBL490608 Show/Hide	C21H17N3O2	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0280680 Compound Info	1-(Methylsulfonyl)-N-[3-(pyridin-4-yl)phenyl]-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C25H26N4O3S	1
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0531890 Compound Info	N-[6-[(4-aminoquinazolin-2-yl)amino]hexyl]naphthalene-1-sulfonamide Show/Hide	C24H27N5O2S	1
1	IC50 = 28 nM Bioactivity Info	TI LI LO TS
CP0526923 Compound Info	1'-(5-fluoro-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H16FN3O2	1
1	IC50 = 28 nM Bioactivity Info	TI LI LO TS
CP0497579 Compound Info	2-N-(4-methoxyphenyl)-4-N-phenylquinazoline-2,4-diamine Show/Hide	C21H18N4O	1
1	IC50 = 33 nM Bioactivity Info	TI LI LO TS
CP0515987 Compound Info	2-N-[4-(diethoxyphosphorylmethyl)phenyl]-4-N-phenylquinazoline-2,4-diamine Show/Hide	C25H27N4O3P	1
1	IC50 = 33 nM Bioactivity Info	TI LI LO TS
CP0489720 Compound Info	1'-(5-methyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C20H19N3O2	1
1	IC50 = 36 nM Bioactivity Info	TI LI LO TS
CP0524170 Compound Info	1'-(5-methoxy-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C20H19N3O3	1
1	IC50 = 37 nM Bioactivity Info	TI LI LO TS
CP0492535 Compound Info	N-[[3-[[(4-aminoquinazolin-2-yl)amino]methyl]cyclohexyl]methyl]naphthalene-1-sulfonamide Show/Hide	C26H29N5O2S	1
1	IC50 = 38 nM Bioactivity Info	TI LI LO TS
CP0462308 Compound Info	4'-(6-chloro-1H-benzimidazol-2-yl)spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C20H17ClN2O2	1
1	IC50 = 39 nM Bioactivity Info	TI LI LO TS
CP0409075 Compound Info	N-[7-[(4-aminoquinazolin-2-yl)amino]heptyl]naphthalene-1-sulfonamide Show/Hide	C25H29N5O2S	1
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
CP0462309 Compound Info	4'-(6-bromo-1H-benzimidazol-2-yl)spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C20H17BrN2O2	1
1	IC50 = 45 nM Bioactivity Info	TI LI LO TS
CP0495778 Compound Info	N-[8-[(4-aminoquinazolin-2-yl)amino]octyl]naphthalene-1-sulfonamide Show/Hide	C26H31N5O2S	1
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
CP0515858 Compound Info	4'-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C21H17F3N2O2	1
1	IC50 = 47 nM Bioactivity Info	TI LI LO TS
CP0455006 Compound Info	2-N-cyclohexyl-4-N-phenylquinazoline-2,4-diamine Show/Hide	C20H22N4	1
1	IC50 = 50 nM Bioactivity Info	TI LI LO TS
CP0528740 Compound Info	2-N-[2-(1-naphthalen-1-ylsulfonylpiperidin-4-yl)ethyl]quinazoline-2,4-diamine Show/Hide	C25H27N5O2S	1
1	IC50 = 51 nM Bioactivity Info	TI LI LO TS
CP0463257 Compound Info	1'-(4-chloro-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H16ClN3O2	1
1	IC50 = 51 nM Bioactivity Info	TI LI LO TS
CP0460323 Compound Info	N-[2-(3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-yl)-3H-benzimidazol-5-yl]methanesulfonamide Show/Hide	C20H20N4O4S	1
1	IC50 = 56 nM Bioactivity Info	TI LI LO TS
CP0463940 Compound Info	N-[[4-[[4-(4-chloroanilino)quinazolin-2-yl]amino]cyclohexyl]methyl]-N-methylacetamide Show/Hide	C24H28ClN5O	1
1	IC50 = 58 nM Bioactivity Info	TI LI LO TS
CP0489723 Compound Info	N,N-dimethyl-2-(3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-yl)-3H-benzimidazole-5-carboxamide Show/Hide	C22H22N4O3	1
1	IC50 = 58 nM Bioactivity Info	TI LI LO TS
CP0458330 Compound Info	N-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]-2,3-dihydro-1H-indene-2-carboxamide Show/Hide	C19H16ClN3O	1
1	IC50 = 59 nM Bioactivity Info	TI LI LO TS
CP0463256 Compound Info	1'-(4-methyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C20H19N3O2	1
1	IC50 = 74 nM Bioactivity Info	TI LI LO TS
CP0138455 Compound Info	2-N,4-N-diphenylquinazoline-2,4-diamine Show/Hide	C20H16N4	1
1	IC50 = 80 nM Bioactivity Info	TI LI LO TS
CP0490171 Compound Info	1'-(4-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C20H16F3N3O2	1
1	IC50 = 83 nM Bioactivity Info	TI LI LO TS
CP0473878 Compound Info	1'-(5-(methylsulfonyl)-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C20H19N3O4S	1
1	IC50 = 85 nM Bioactivity Info	TI LI LO TS
CP0388294 Compound Info	4'-(1H-imidazo[4,5-b]pyridin-2-yl)spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C19H17N3O2	1
1	IC50 = 91 nM Bioactivity Info	TI LI LO TS
CP0514763 Compound Info	4'-(1H-benzimidazol-2-yl)spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C20H18N2O2	1
1	IC50 = 91 nM Bioactivity Info	TI LI LO TS
CP0454996 Compound Info	2-N-(4-chlorophenyl)-4-N-phenylquinazoline-2,4-diamine Show/Hide	C20H15ClN4	1
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0511101 Compound Info	N-[[4-[[(4-aminoquinazolin-2-yl)amino]methyl]cyclohexyl]methyl]-N-methylnaphthalene-1-sulfonamide Show/Hide	C27H31N5O2S	1
1	IC50 = 110 nM Bioactivity Info	TI LI LO TS
CP0489722 Compound Info	2-(3-oxo-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)-1H-benzo[d]imidazole-5-carboxamide Show/Hide	C20H18N4O3	1
1	IC50 = 110 nM Bioactivity Info	TI LI LO TS
CP0490172 Compound Info	N-[2-(3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-yl)-3H-benzimidazol-5-yl]acetamide Show/Hide	C21H20N4O3	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0524169 Compound Info	1'-(1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H17N3O2	1
1	IC50 = 140 nM Bioactivity Info	TI LI LO TS
CP0490180 Compound Info	2-(biphenyl-4-yl)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidine]-1'-yl)ethanone Show/Hide	C27H28N2O3S	1
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0506587 Compound Info	2-N-(4-methylphenyl)-4-N-phenylquinazoline-2,4-diamine Show/Hide	C21H18N4	1
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0375131 Compound Info	1-methylsulfonyl-N-(4-phenylphenyl)spiro[2H-indole-3,4'-cyclohexane]-1'-carboxamide Show/Hide	C27H28N2O3S	1
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0559753 Compound Info	N-[[4-[[4-(4-chloroanilino)quinazolin-2-yl]amino]cyclohexyl]methyl]-N-methylbenzamide Show/Hide	C29H30ClN5O	1
1	IC50 = 250 nM Bioactivity Info	TI LI LO TS
CP0528455 Compound Info	1'-(4-methoxy-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C20H19N3O3	1
1	IC50 = 250 nM Bioactivity Info	TI LI LO TS
CP0510056 Compound Info	2-N-(3,4-dichlorophenyl)-4-N-phenylquinazoline-2,4-diamine Show/Hide	C20H14Cl2N4	1
1	IC50 = 270 nM Bioactivity Info	TI LI LO TS
CP0432844 Compound Info	N-[[4-[[(4-aminoquinazolin-2-yl)amino]methyl]phenyl]methyl]naphthalene-1-sulfonamide Show/Hide	C26H23N5O2S	1
1	IC50 = 290 nM Bioactivity Info	TI LI LO TS
CP0514388 Compound Info	N-[[4-[[4-(4-chloroanilino)quinazolin-2-yl]amino]cyclohexyl]methyl]benzamide Show/Hide	C28H28ClN5O	1
1	IC50 = 310 nM Bioactivity Info	TI LI LO TS
CP0507043 Compound Info	N-[[3-[[(4-aminoquinazolin-2-yl)amino]methyl]phenyl]methyl]naphthalene-1-sulfonamide Show/Hide	C26H23N5O2S	1
1	IC50 = 380 nM Bioactivity Info	TI LI LO TS
CP0562227 Compound Info	N-[[4-[[4-(4-chloroanilino)quinazolin-2-yl]amino]cyclohexyl]methyl]acetamide Show/Hide	C23H26ClN5O	1
1	IC50 = 390 nM Bioactivity Info	TI LI LO TS
CP0507093 Compound Info	Benzoic acid 4-(4-phenylamino-quinazolin-2-ylamino)-cyclohexyl ester Show/Hide	C27H26N4O2	1
1	IC50 = 400 nM Bioactivity Info	TI LI LO TS
CP0386234 Compound Info	1-methylsulfonyl-N-(2-phenylphenyl)spiro[2H-indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C26H27N3O3S	1
1	IC50 = 430 nM Bioactivity Info	TI LI LO TS
CP0526922 Compound Info	1'-(4-fluoro-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H16FN3O2	1
1	IC50 = 500 nM Bioactivity Info	TI LI LO TS
CP0534149 Compound Info	4-N-(4-chlorophenyl)-2-N-[4-(methylaminomethyl)cyclohexyl]quinazoline-2,4-diamine Show/Hide	C22H26ClN5	1
1	IC50 = 510 nM Bioactivity Info	TI LI LO TS
CP0461708 Compound Info	N-[[4-[[(4-aminoquinazolin-2-yl)-methylamino]methyl]cyclohexyl]methyl]-N-methylnaphthalene-1-sulfonamide Show/Hide	C28H33N5O2S	1
1	IC50 = 710 nM Bioactivity Info	TI LI LO TS
CP0522872 Compound Info	methyl 6-chloro-2-(3-oxospiro[2-benzofuran-1,4'-cyclohexane]-1'-yl)-1H-benzimidazole-5-carboxylate Show/Hide	C22H19ClN2O4	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0541906 Compound Info	4'-[6-(5-methyl-1,3,4-oxadiazol-2-yl)-1H-benzimidazol-2-yl]spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C23H20N4O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0440622 Compound Info	4'-(1H-imidazo[4,5-b]pyridin-2-yl)spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C19H17N3O2	1
1	IC50 = 1400 nM Bioactivity Info	TI LI LO TS
CP0377444 Compound Info	1'-(3H-imidazo[4,5-b]pyridin-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C18H16N4O2	1
1	IC50 = 1600 nM Bioactivity Info	TI LI LO TS
CP0514360 Compound Info	N-[(1R,2S)-2-[(4-aminoquinazolin-2-yl)amino]cyclohexyl]naphthalene-1-sulfonamide Show/Hide	C24H25N5O2S	1
1	IC50 = 4900 nM Bioactivity Info	TI LI LO TS
CP0526905 Compound Info	1'-((1H-benzo[d]imidazol-2-yl)methyl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C20H19N3O2	1
1	IC50 = 4900 nM Bioactivity Info	TI LI LO TS
CP0457514 Compound Info	1'-(benzo[d]thiazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one Show/Hide	C19H16N2O2S	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0443335 Compound Info	2-methyl-3-oxo-N-(5-phenylpyrazin-2-yl)spiro[isoindoline-1,4'-piperidine]-1'-carboxamide Show/Hide	C24H23N5O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0496659 Compound Info	1-oxo-N-(5-phenylpyrazin-2-yl)-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxamide Show/Hide	C24H23N5O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0504019 Compound Info	N-(5-phenylpyrazin-2-yl)spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-carboxamide Show/Hide	C24H24N4O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0514508 Compound Info	N-(5-phenylpyrazin-2-yl)spiro[1H-2-benzofuran-3,4'-piperidine]-1'-carboxamide Show/Hide	C23H22N4O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0398946 Compound Info	2-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidine]-1'-yl)-1H-benzo[d]imidazole Show/Hide	C20H22N4O2S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0519779 Compound Info	2-(3-oxo-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)-1H-benzo[d]imidazole-5-carboxylic acid Show/Hide	C20H17N3O4	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0467663 Compound Info	4'-(5,6-dichloro-1-methylbenzimidazol-2-yl)spiro[2-benzofuran-3,1'-cyclohexane]-1-one Show/Hide	C21H18Cl2N2O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0399808 Compound Info	3-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]benzonitrile Show/Hide	C22H16F2N4	1
1	Ki = 0.8 nM Bioactivity Info	TI LI LO TS
CP0434193 Compound Info	2-[(5S)-4,4-Bis(4-fluorophenyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile Show/Hide	C22H16F2N4	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0485244 Compound Info	4-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-2-pyridinecarbonitrile Show/Hide	C21H15F2N5	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0919384 Compound Info	2-{(4S,5S)-4-(4-Fluorophenyl)-5-methyl-4-[6-(methyloxy)-3-pyridyl]-4,5-dihydro-1H-imidazol-2-yl}-4-pyridinecarbonitrile Hydrochloride Show/Hide	C22H19ClFN5O	1
1	Ki = 1.1 nM Bioactivity Info	TI LI LO TS
CP0127467 Compound Info	2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile Show/Hide	C21H15F2N5	1
1	Ki = 1.3 nM Bioactivity Info	TI LI LO TS
CP0459566 Compound Info	6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-2(1H)-pyridinone Show/Hide	C20H16F2N4O	1
1	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
CP0434195 Compound Info	2-[(4R,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile Show/Hide	C21H15F2N5	1
1	Ki = 1.6 nM Bioactivity Info	TI LI LO TS
CP0904967 Compound Info	4-Chloro-2-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridine Hydrochloride Show/Hide	C20H16Cl2F2N4	1
1	Ki = 1.8 nM Bioactivity Info	TI LI LO TS
CP0904966 Compound Info	2-[(5S)-4,4-Bis(4-fluorophenyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyrazine Hydrochloride Show/Hide	C20H17ClF2N4	1
1	Ki = 1.9 nM Bioactivity Info	TI LI LO TS
CP0473714 Compound Info	2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)isonicotinonitrile Show/Hide	C21H14F2N4	1
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0490669 Compound Info	2-Fluoro-5-[(4S,5S)-4-(4-fluorophenyl)-5-methyl-2-(1,2,5-thiadiazol-3-yl)-4,5-dihydro-1H-imidazol-4-yl]pyridine Show/Hide	C17H13F2N5S	1
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0443318 Compound Info	N-[5-(3,5-difluorophenyl)pyridin-2-yl]-4-(2-oxopiperidin-1-yl)cyclohexane-1-carboxamide Show/Hide	C23H25F2N3O2	1
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0505577 Compound Info	2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyrazine Show/Hide	C19H15F2N5	1
1	Ki = 2.2 nM Bioactivity Info	TI LI LO TS
CP0437721 Compound Info	2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-(methyloxy)pyridine Show/Hide	C21H18F2N4O	1
1	Ki = 2.5 nM Bioactivity Info	TI LI LO TS
CP0511878 Compound Info	2-Fluoro-5-{(4S,5S)-4-(4-fluorophenyl)-5-methyl-2-[3-(methylsulfonyl) phenyl]-4,5-dihydro-1H-imidazol-4-yl}pyridine Show/Hide	C22H19F2N3O2S	1
1	Ki = 2.5 nM Bioactivity Info	TI LI LO TS
CP0502257 Compound Info	2-[(5S)-5-Ethyl-4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile Show/Hide	C23H18F2N4	1
1	Ki = 2.6 nM Bioactivity Info	TI LI LO TS
CP0424876 Compound Info	6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-3-methylpyridin-2(1H)-one Show/Hide	C21H18F2N4O	1
1	Ki = 2.6 nM Bioactivity Info	TI LI LO TS
CP0541602 Compound Info	1-Ethyl-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one Show/Hide	C22H20F2N4O	1
1	Ki = 2.9 nM Bioactivity Info	TI LI LO TS
CP0387829 Compound Info	2-[(5R)-4,4-Bis(4-fluorophenyl)-5-(hydroxymethyl)-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile Show/Hide	C22H16F2N4O	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0501005 Compound Info	N-[5-(3,5-difluorophenyl)pyridin-2-yl]-4-[(5R)-5-methyl-2-oxo-1,3-oxazolidin-3-yl]cyclohexane-1-carboxamide Show/Hide	C22H23F2N3O3	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0476190 Compound Info	2-[(5S)-4,4-Bis(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile Show/Hide	C20H14F2N6	1
1	Ki = 3.1 nM Bioactivity Info	TI LI LO TS
CP0510505 Compound Info	5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-3-pyridinecarbonitrile Show/Hide	C21H15F2N5	1
1	Ki = 3.2 nM Bioactivity Info	TI LI LO TS
CP0489815 Compound Info	3-Chloro-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one Show/Hide	C20H15ClF2N4O	1
1	Ki = 3.4 nM Bioactivity Info	TI LI LO TS
CP0476191 Compound Info	2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-pyrimidinecarbonitrile Show/Hide	C20H14F2N6	1
1	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0499164 Compound Info	5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-1-(propan-2-yl)pyridin-2(1H)-one Show/Hide	C23H22F2N4O	1
1	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0499163 Compound Info	5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-3-(trifluoromethyl)-pyridin-2(1H)-one Show/Hide	C21H15F5N4O	1
1	Ki = 3.8 nM Bioactivity Info	TI LI LO TS
CP0489465 Compound Info	4-(5-tert-butyl-2-oxo-1,3-oxazolidin-3-yl)-N-[5-(3,5-difluorophenyl)pyridin-2-yl]cyclohexane-1-carboxamide Show/Hide	C25H29F2N3O3	1
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0538607 Compound Info	2-Fluoro-5-[(4S,5S)-4-(4-fluorophenyl)-5-methyl-2-(1,3-thiazol-2-yl)-4,5-dihydro-1H-imidazol-4-yl]pyridine Show/Hide	C18H14F2N4S	1
1	Ki = 4.1 nM Bioactivity Info	TI LI LO TS
CP0235801 Compound Info	2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyrazine Show/Hide	C19H14F2N4	1
1	Ki = 4.3 nM Bioactivity Info	TI LI LO TS
CP0512567 Compound Info	5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-3-methylpyridin-2(1H)-one Show/Hide	C21H18F2N4O	1
1	Ki = 4.3 nM Bioactivity Info	TI LI LO TS
CP0504786 Compound Info	5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-1-propylpyridin-2(1H)-one Show/Hide	C23H22F2N4O	1
1	Ki = 4.7 nM Bioactivity Info	TI LI LO TS
CP0495179 Compound Info	5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-3-methoxypyridin-2(1H)-one Show/Hide	C21H18F2N4O2	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0379664 Compound Info	CHEMBL3126047 Show/Hide	C22H24F2N4O2	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0489464 Compound Info	N-[5-(3,5-difluorophenyl)pyridin-2-yl]-4-(2-oxoimidazolidin-1-yl)cyclohexane-1-carboxamide Show/Hide	C21H22F2N4O2	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0572168 Compound Info	N-[5-(3,5-difluorophenyl)pyrimidin-2-yl]-4-(2-oxopyrrolidin-1-yl)cyclohexane-1-carboxamide Show/Hide	C21H22F2N4O2	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0476192 Compound Info	2-((4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl)isonicotinamide Show/Hide	C21H17F2N5O	1
1	Ki = 5.1 nM Bioactivity Info	TI LI LO TS
CP0510506 Compound Info	6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-2-pyridinecarbonitrile Show/Hide	C21H15F2N5	1
1	Ki = 5.9 nM Bioactivity Info	TI LI LO TS
CP0487076 Compound Info	N-[5-(3,5-difluorophenyl)pyrazin-2-yl]-4-(2-oxopyrrolidin-1-yl)cyclohexane-1-carboxamide Show/Hide	C21H22F2N4O2	1
1	Ki = 6 nM Bioactivity Info	TI LI LO TS
CP0524797 Compound Info	1-Ethyl-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-3-methylpyridin-2(1H)-one Show/Hide	C23H22F2N4O	1
1	Ki = 6.6 nM Bioactivity Info	TI LI LO TS
CP0473422 Compound Info	3-Fluoro-6-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one Show/Hide	C20H15F3N4O	1
1	Ki = 6.9 nM Bioactivity Info	TI LI LO TS
CP0566243 Compound Info	N-[5-(3,5-difluorophenyl)pyridin-2-yl]-4-[(5S)-5-methyl-2-oxo-1,3-oxazolidin-3-yl]cyclohexane-1-carboxamide Show/Hide	C22H23F2N3O3	1
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
CP0464486 Compound Info	1-Ethoxy-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one Show/Hide	C22H20F2N4O2	1
1	Ki = 7.3 nM Bioactivity Info	TI LI LO TS
CP0530490 Compound Info	5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one Show/Hide	C20H16F2N4O	1
1	Ki = 7.4 nM Bioactivity Info	TI LI LO TS
CP0487075 Compound Info	CHEMBL3126042 Show/Hide	C21H21F2N3O3	1
1	Ki = 8 nM Bioactivity Info	TI LI LO TS
CP0572167 Compound Info	N-[5-(3,5-difluorophenyl)pyridin-2-yl]-4-(2-oxopyrrolidin-1-yl)cyclohexane-1-carboxamide Show/Hide	C22H23F2N3O2	1
1	Ki = 8 nM Bioactivity Info	TI LI LO TS
CP0474976 Compound Info	1-(Difluoromethyl)-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-3-methylpyridin-2(1H)-one Show/Hide	C22H18F4N4O	1
1	Ki = 8.5 nM Bioactivity Info	TI LI LO TS
CP0387827 Compound Info	2-[(5S)-4,4-Bis(4-fluorophenyl)-5-propyl-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile Show/Hide	C24H20F2N4	1
1	Ki = 8.6 nM Bioactivity Info	TI LI LO TS
CP0473421 Compound Info	6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-methylpyridin-2(1H)-one Show/Hide	C21H18F2N4O	1
1	Ki = 8.6 nM Bioactivity Info	TI LI LO TS
CP0486294 Compound Info	3-Chloro-6-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one Show/Hide	C20H15ClF2N4O	1
1	Ki = 8.6 nM Bioactivity Info	TI LI LO TS
CP0489463 Compound Info	N-[5-(3,5-difluorophenyl)pyridin-2-yl]-4-(2-oxo-1,3-diazinan-1-yl)cyclohexane-1-carboxamide Show/Hide	C22H24F2N4O2	1
1	Ki = 9 nM Bioactivity Info	TI LI LO TS
CP0549444 Compound Info	4-(3-cyclopropyl-2-oxoimidazolidin-1-yl)-N-[5-(3,5-difluorophenyl)pyridin-2-yl]cyclohexane-1-carboxamide Show/Hide	C24H26F2N4O2	1
1	Ki = 9 nM Bioactivity Info	TI LI LO TS
CP0379661 Compound Info	N-[5-(3,5-difluorophenyl)pyridin-2-yl]-4-(3-ethyl-2-oxoimidazolidin-1-yl)cyclohexane-1-carboxamide Show/Hide	C23H26F2N4O2	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0460232 Compound Info	3-Fluoro-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one Show/Hide	C20H15F3N4O	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0379699 Compound Info	N-[5-(3,5-difluorophenyl)pyridin-2-yl]-4-(3-methyl-2-oxo-1,3-diazinan-1-yl)cyclohexane-1-carboxamide Show/Hide	C23H26F2N4O2	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0503087 Compound Info	5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-1-methylpyridin-2(1H)-one Show/Hide	C21H18F2N4O	1
1	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0521764 Compound Info	6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-5-methylpyridin-2(1H)-one Show/Hide	C21H18F2N4O	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0659250 Compound Info	9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-enyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one Show/Hide	C23H26O4	1
1	Ki = 33 nM Bioactivity Info	TI LI LO TS
CP0379659 Compound Info	N-[5-(3,5-difluorophenyl)pyridin-2-yl]-4-(2-oxo-3-propan-2-ylimidazolidin-1-yl)cyclohexane-1-carboxamide Show/Hide	C24H28F2N4O2	1
1	Ki = 41 nM Bioactivity Info	TI LI LO TS
CP0475924 Compound Info	4-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one Show/Hide	C20H16F2N4O	1
1	Ki = 42 nM Bioactivity Info	TI LI LO TS
CP0505576 Compound Info	2-[(4S,5S)-4-(4-Fluorophenyl)-5-methyl-4-(6-oxo-1,6-dihydro-3-pyridyl)-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile Show/Hide	C21H16FN5O	1
1	Ki = 145 nM Bioactivity Info	TI LI LO TS
CP0476189 Compound Info	2-[(5R)-4,4-Bis(4-fluorophenyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile Show/Hide	C22H16F2N4	1
1	Ki = 300 nM Bioactivity Info	TI LI LO TS
CP0476003 Compound Info	6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-1-methylpyridin-2(1H)-one Show/Hide	C21H18F2N4O	1
1	Ki = 350 nM Bioactivity Info	TI LI LO TS
CP0489775 Compound Info	3-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one Show/Hide	C20H16F2N4O	1
1	Ki = 600 nM Bioactivity Info	TI LI LO TS
CP0877872 Compound Info	5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-methylpyridin-2(1H)-one trifluoroacetate Show/Hide	C23H19F5N4O3	1
1	Ki = 630 nM Bioactivity Info	TI LI LO TS
CP0489462 Compound Info	N-[5-(3,5-difluorophenyl)pyridin-2-yl]-4-(2-oxopyrrolidin-1-yl)cyclohexane-1-carboxamide Show/Hide	C22H23F2N3O2	1
1	Ki = 720 nM Bioactivity Info	TI LI LO TS
CP0549443 Compound Info	N-[5-(3,5-difluorophenyl)pyridin-2-yl]-N-methyl-4-(2-oxopyrrolidin-1-yl)cyclohexane-1-carboxamide Show/Hide	C23H25F2N3O2	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0522020 Compound Info	6-Fluoro-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one Show/Hide	C20H15F3N4O	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS

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About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han