Brief Information of the Compound and Protein
Compound Name
1-(Difluoromethyl)-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]pyridin-2(1H)-one
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PubChem ID
CID: 10047509
SID: 15030987
Canonical SMILES
C[C@@H]1NC(=N[C@@]1(c1ccc(F)cc1)c1ccc(F)nc1)c1ccc(=O)n(c1)C(F)F
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Compound Formula C21H16F4N4O
Compound Structure
Protein Name
Neuropeptide Y receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide Y receptor
Uniprot ID
Q15761
Gene Name
NPY5R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000101 L-M(TK-) Mus musculus (Mouse)  2
1
IC50 = 8.7 nM
   TI
   LI
   LO
   TS
2
Ki = 2.8 nM
   TI
   LI
   LO
   TS