All Bioactivity

Brief Information of the Cell Line and Protein

Cell Line ID: CL000006 , HEK293

Cell Line Info

Synonyms	Hek293 HEK-293 HEK/293 HEK 293 HEK;293 293 293 HEK 293 Ad5 Graham 293 Graham-293 Human Embryonic Kidney 293
Category	Transformed cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_0045

Protein ID: PT01795 , Neuropeptide Y receptor type 5

Protein Info

Gene Name	NPY5R
Organism	Homo sapiens, Human
Protein Classification	Membrane receptor
Uniprot ID	Q15761

Table of Molecular Bioactivities Related to the Cell Line and Protein

Cell Line ID: CL000006

Cell Line Info

Protein ID: PT01795

Protein Info

Compound ID	Compound Name	Compound Formula
CP0407337 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C180H279N53O54	2
1	EC50 = 8.2 nM Bioactivity Info	TI LI LO TS
2	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0395746 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]oxy-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C177H272N52O55	1
1	EC50 = 29 nM Bioactivity Info	TI LI LO TS
CP0201266 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]-methylamino]-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C181H280N52O55	2
1	EC50 = 100 nM Bioactivity Info	TI LI LO TS
2	Ki = 100 nM Bioactivity Info	TI LI LO TS
CP0429604 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]oxy-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C177H272N52O55	1
1	EC50 = 112 nM Bioactivity Info	TI LI LO TS
CP0381781 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]oxy-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C177H272N52O55	1
1	EC50 = 172 nM Bioactivity Info	TI LI LO TS
CP0415441 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]oxy-1,5-dioxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C177H272N52O55	1
1	EC50 = 187 nM Bioactivity Info	TI LI LO TS
CP0381997 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]oxy-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C177H272N52O55	1
1	EC50 > 500 nM Bioactivity Info	TI LI LO TS
CP0429744 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]oxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C177H272N52O55	1
1	EC50 > 500 nM Bioactivity Info	TI LI LO TS
CP0405548 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(3S)-6-carbamimidamido-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-1-oxohexan-3-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C181H280N52O55	1
1	EC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0438084 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid (4-chloro-naphthalen-1-yl)-amide Show/Hide	C25H21Cl2N3O3S	1
1	IC50 = 0.23 nM Bioactivity Info	TI LI LO TS
CP0206845 Compound Info	2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-N-(9-oxo-9H-fluoren-3-yl)-acetamide Show/Hide	C27H24N4O3	1
1	IC50 = 0.47 nM Bioactivity Info	TI LI LO TS
CP0401057 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid (4-fluoro-3-trifluoromethyl-phenyl)-amide Show/Hide	C22H18ClF4N3O3S	2
1	IC50 = 0.59 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.7 nM Bioactivity Info	TI LI LO TS
CP0430119 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid (3-acetyl-phenyl)-amide Show/Hide	C23H22ClN3O4S	2
1	IC50 = 0.59 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0391535 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid naphthalen-1-ylamide Show/Hide	C25H22ClN3O3S	2
1	IC50 = 0.71 nM Bioactivity Info	TI LI LO TS
2	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0463683 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid (4-phenoxy-phenyl)-amide Show/Hide	C27H24ClN3O4S	2
1	IC50 = 0.85 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.5 nM Bioactivity Info	TI LI LO TS
CP0460880 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid (3-benzoyl-phenyl)-amide Show/Hide	C28H24ClN3O4S	2
1	IC50 = 0.89 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
CP0511651 Compound Info	N-[[4-[[(7-hydroxy-1,3,3a,4,5,9b-hexahydrobenzo[e]indol-2-ylidene)amino]methyl]cyclohexyl]methyl]benzenesulfonamide Show/Hide	C26H33N3O3S	1
1	IC50 = 1 nM Bioactivity Info	TI LI LO TS
CP0494142 Compound Info	N-[(5S)-5-amino-6-[[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]amino]hexyl]-2-fluorobenzenesulfonamide Show/Hide	C28H35FN4O3S	1
1	IC50 = 1 nM Bioactivity Info	TI LI LO TS
CP0448564 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid (2-hydroxy-2-phenyl-ethyl)-amide Show/Hide	C23H24ClN3O4S	2
1	IC50 = 1.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.2 nM Bioactivity Info	TI LI LO TS
CP0294550 Compound Info	N-[1-(2-fluorophenyl)pyrazol-3-yl]-1'-oxospiro[cyclohexane-4,3'-furo[3,4-c]pyridine]-1-carboxamide Show/Hide	C22H19FN4O3	1
1	IC50 = 1.259 nM Bioactivity Info	TI LI LO TS
CP0384015 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid decylamide Show/Hide	C25H36ClN3O3S	2
1	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.6 nM Bioactivity Info	TI LI LO TS
CP0376431 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid 4-methoxy-benzylamide Show/Hide	C23H24ClN3O4S	2
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.3 nM Bioactivity Info	TI LI LO TS
CP0391909 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid (4-hydroxy-2-methyl-phenyl)-amide Show/Hide	C22H22ClN3O4S	2
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4.7 nM Bioactivity Info	TI LI LO TS
CP0463244 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid [4-(2-hydroxy-ethyl)-phenyl]-amide Show/Hide	C23H24ClN3O4S	2
1	IC50 = 1.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0421514 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid (6-methoxy-pyridin-3-yl)-amide Show/Hide	C21H21ClN4O4S	2
1	IC50 = 2.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.6 nM Bioactivity Info	TI LI LO TS
CP0463294 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid (6-methyl-benzothiazol-2-yl)-amide Show/Hide	C23H21ClN4O3S2	2
1	IC50 = 2.8 nM Bioactivity Info	TI LI LO TS
2	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0055951 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S,3S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-4-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C189H285N55O57S	1
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0502398 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid [2-hydroxy-2-(6-methyl-pyridin-2-yl)-ethyl]-amide Show/Hide	C23H25ClN4O4S	1
1	IC50 = 3.3 nM Bioactivity Info	TI LI LO TS
CP0486334 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid (5-chloro-benzooxazol-2-yl)-amide Show/Hide	C22H18Cl2N4O4S	2
1	IC50 = 3.8 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4.7 nM Bioactivity Info	TI LI LO TS
CP0468276 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid phenylamide Show/Hide	C21H20ClN3O3S	1
1	IC50 = 4.4 nM Bioactivity Info	TI LI LO TS
CP0511591 Compound Info	2-(3-Benzenesulfonylamino-pyrrolidin-1-yl)-N-(6-fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-acetamide Show/Hide	C28H31FN4O3S	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0905324 Compound Info	N-{4-[(1-Allyl-6-hydroxy-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-methyl]-cyclohexylmethyl}-benzenesulfonamide Show/Hide	C27H36N2O3S	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0377584 Compound Info	N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]acetamide Show/Hide	C30H33N5O3	1
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0460792 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid [2-(4-sulfamoyl-phenyl)-ethyl]-amide Show/Hide	C23H25ClN4O5S2	2
1	IC50 = 6.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0860728 Compound Info	2-Fluoro-N-{4-[(6-hydroxy-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-methyl]-cyclohexylmethyl}-benzenesulfonamide Show/Hide	C30H36FN3O3S	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0475660 Compound Info	4-(Benzenesulfonylamino-methyl)-cyclohexanecarboxylic acid (7-hydroxy-3a,4,5,9b-tetrahydro-1H-benzo[e]indol-2-yl)-amide Show/Hide	C26H31N3O4S	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0505810 Compound Info	2-(4-Benzenesulfonylamino-piperidin-1-yl)-N-(6-fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-acetamide Show/Hide	C29H33FN4O3S	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0940703 Compound Info	N-{4-[(6-Methoxy-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-methyl]-cyclohexylmethyl}-benzenesulfonamide Show/Hide	C31H39N3O3S	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0488940 Compound Info	N-[[4-[5-amino-1-[4-(trifluoromethyl)phenyl]pyrazol-3-yl]cyclohexyl]methyl]-2-nitrobenzenesulfonamide Show/Hide	C23H24F3N5O4S	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0505896 Compound Info	N-[[4-[5-amino-1-[3-(trifluoromethyl)phenyl]pyrazol-3-yl]cyclohexyl]methyl]-2-nitrobenzenesulfonamide Show/Hide	C23H24F3N5O4S	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0467601 Compound Info	2-(3-Benzenesulfonylamino-pyrrolidin-1-yl)-N-(6-fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-acetamide Show/Hide	C28H31FN4O3S	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0845192 Compound Info	4-[(2-Fluoro-benzenesulfonylamino)-methyl]-cyclohexanecarboxylic acid (6-methoxy-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amide Show/Hide	C31H36FN3O4S	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0953756 Compound Info	4-(Benzenesulfonylamino-methyl)-cyclohexanecarboxylic acid (6-methoxy-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amide Show/Hide	C31H37N3O4S	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0941498 Compound Info	4-[(2-Fluoro-benzenesulfonylamino)-methyl]-cyclohexanecarboxylic acid (6-fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amide Show/Hide	C30H33F2N3O3S	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0482865 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-4-methoxybenzenesulfonamide Show/Hide	C23H22N4O3S	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0511201 Compound Info	tert-butyl N-[[4-[[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]carbamoyl]cyclohexyl]methyl]carbamate Show/Hide	C29H38FN3O3	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0453392 Compound Info	tert-butyl N-[(3S)-1-[2-[[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-2-oxoethyl]pyrrolidin-3-yl]carbamate Show/Hide	C27H35FN4O3	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0944619 Compound Info	2-Fluoro-N-{4-[(6-fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-methyl]-cyclohexylmethyl}-benzenesulfonamide Show/Hide	C30H35F2N3O2S	1
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0395531 Compound Info	2-Amino-N-{4-[5-amino-1-(4-trifluoromethyl-phenyl)-1H-pyrazol-3-yl]-cyclohexylmethyl}-benzenesulfonamide Show/Hide	C23H26F3N5O2S	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0916093 Compound Info	N-{4-[(1-Allyl-6-fluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-methyl]-cyclohexylmethyl}-benzenesulfonamide Show/Hide	C27H35FN2O2S	1
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
CP0457128 Compound Info	2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-N-(1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-acetamide Show/Hide	C30H33N5O2	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0453403 Compound Info	2-Amino-6-(2-fluoro-benzenesulfonylamino)-hexanoic acid (6-fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amide Show/Hide	C28H32F2N4O3S	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0946874 Compound Info	2-Fluoro-N-{4-[(6-methoxy-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-methyl]-cyclohexylmethyl}-benzenesulfonamide Show/Hide	C31H38FN3O3S	1
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0534408 Compound Info	N-[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]acetamide Show/Hide	C30H32FN5O2	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0501039 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]benzenesulfonamide Show/Hide	C22H20N4O2S	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0539575 Compound Info	N-[(3S)-1-[2-[[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-2-oxoethyl]pyrrolidin-3-yl]benzamide Show/Hide	C29H31FN4O2	1
1	IC50 = 26 nM Bioactivity Info	TI LI LO TS
CP0377747 Compound Info	2-(3-Benzenesulfonylamino-pyrrolidin-1-yl)-N-(6-fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-acetamide Show/Hide	C28H31FN4O3S	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0928362 Compound Info	N-{4-[(6-Fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-methyl]-cyclohexylmethyl}-benzenesulfonamide Show/Hide	C30H36FN3O2S	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0461176 Compound Info	N-[1-[2-[[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-2-oxoethyl]piperidin-4-yl]benzamide Show/Hide	C30H33FN4O2	1
1	IC50 = 28 nM Bioactivity Info	TI LI LO TS
CP0470675 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-4-fluorobenzenesulfonamide Show/Hide	C22H19FN4O2S	1
1	IC50 = 29 nM Bioactivity Info	TI LI LO TS
CP0383090 Compound Info	tert-butyl N-[(3R)-1-[2-[[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-2-oxoethyl]pyrrolidin-3-yl]carbamate Show/Hide	C27H35FN4O3	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0540345 Compound Info	N-[4-[5-amino-1-[3-(dimethylamino)phenyl]pyrazol-3-yl]phenyl]-4-methoxybenzenesulfonamide Show/Hide	C24H25N5O3S	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0448296 Compound Info	phenyl N-[[4-[[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]carbamoyl]cyclohexyl]methyl]carbamate Show/Hide	C31H34FN3O3	1
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0430117 Compound Info	2-Fluoro-N-{4-[(7-methoxy-3a,4,5,9b-tetrahydro-1H-benzo[e]indol-2-ylamino)-methyl]-cyclohexylmethyl}-benzenesulfonamide Show/Hide	C27H34FN3O3S	1
1	IC50 = 35 nM Bioactivity Info	TI LI LO TS
CP0461178 Compound Info	N-[1-[2-[[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-2-oxoethyl]piperidin-4-yl]-2-phenylacetamide Show/Hide	C31H35FN4O2	1
1	IC50 = 36 nM Bioactivity Info	TI LI LO TS
CP0465722 Compound Info	tert-butyl N-[1-[2-[[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-2-oxoethyl]piperidin-4-yl]carbamate Show/Hide	C28H37FN4O3	1
1	IC50 = 37 nM Bioactivity Info	TI LI LO TS
CP0406837 Compound Info	N-[4-[5-amino-1-(3-methylphenyl)pyrazol-3-yl]phenyl]-4-methoxybenzenesulfonamide Show/Hide	C23H22N4O3S	1
1	IC50 = 37 nM Bioactivity Info	TI LI LO TS
CP0500407 Compound Info	N-[4-[5-amino-1-(4-fluorophenyl)pyrazol-3-yl]phenyl]-4-methoxybenzenesulfonamide Show/Hide	C22H19FN4O3S	1
1	IC50 = 37 nM Bioactivity Info	TI LI LO TS
CP0895143 Compound Info	N-{4-[(3a,4,5,9b-Tetrahydro-1H-benzo[e]indol-2-ylamino)-methyl]-cyclohexylmethyl}-benzenesulfonamide Show/Hide	C26H34ClN3O2S	1
1	IC50 = 39 nM Bioactivity Info	TI LI LO TS
CP0540314 Compound Info	N-[[4-[[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]carbamoyl]cyclohexyl]methyl]benzamide Show/Hide	C31H34FN3O2	1
1	IC50 = 39 nM Bioactivity Info	TI LI LO TS
CP0895207 Compound Info	4-(Benzenesulfonylamino-methyl)-cyclohexanecarboxylic acid (6-fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amide Show/Hide	C30H34FN3O3S	1
1	IC50 = 40 nM Bioactivity Info	TI LI LO TS
CP0521157 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-4-methylbenzenesulfonamide Show/Hide	C23H22N4O2S	1
1	IC50 = 40 nM Bioactivity Info	TI LI LO TS
CP0406967 Compound Info	tert-butyl N-[1-[2-[[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-2-oxoethyl]pyrrolidin-3-yl]carbamate Show/Hide	C27H35FN4O3	1
1	IC50 = 45 nM Bioactivity Info	TI LI LO TS
CP0521162 Compound Info	N-[4-(5-amino-1-naphthalen-1-ylpyrazol-3-yl)phenyl]-4-methoxybenzenesulfonamide Show/Hide	C26H22N4O3S	1
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0376453 Compound Info	phenyl N-[1-[2-[[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-2-oxoethyl]piperidin-4-yl]carbamate Show/Hide	C30H33FN4O3	1
1	IC50 = 52 nM Bioactivity Info	TI LI LO TS
CP0374734 Compound Info	N-[6-[[6-methoxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]amino]hexyl]benzenesulfonamide Show/Hide	C29H37N3O3S	1
1	IC50 = 53 nM Bioactivity Info	TI LI LO TS
CP0193575 Compound Info	1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid thiazol-2-ylamide Show/Hide	C18H17ClN4O3S2	1
1	IC50 = 53 nM Bioactivity Info	TI LI LO TS
CP0401060 Compound Info	N-[[4-[[(7-chloro-1,3,3a,4,5,9b-hexahydrobenzo[e]indol-2-ylidene)amino]methyl]cyclohexyl]methyl]benzenesulfonamide Show/Hide	C26H32ClN3O2S	1
1	IC50 = 54 nM Bioactivity Info	TI LI LO TS
CP0541996 Compound Info	N-[[4-[[(7-methoxy-1,3,3a,4,5,9b-hexahydrobenzo[e]indol-2-ylidene)amino]methyl]cyclohexyl]methyl]benzenesulfonamide Show/Hide	C27H35N3O3S	1
1	IC50 = 57 nM Bioactivity Info	TI LI LO TS
CP0498066 Compound Info	4-(Benzenesulfonylamino-methyl)-cyclohexanecarboxylic acid (3a,4,5,9b-tetrahydro-1H-benzo[e]indol-2-yl)-amide Show/Hide	C26H31N3O3S	1
1	IC50 = 60 nM Bioactivity Info	TI LI LO TS
CP0406763 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-4-(trifluoromethyl)benzenesulfonamide Show/Hide	C23H19F3N4O2S	1
1	IC50 = 63 nM Bioactivity Info	TI LI LO TS
CP0530234 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-4-(trifluoromethoxy)benzenesulfonamide Show/Hide	C23H19F3N4O3S	1
1	IC50 = 67 nM Bioactivity Info	TI LI LO TS
CP0540346 Compound Info	4-Amino-N-[4-(5-amino-1-p-tolyl-1H-pyrazol-3-yl)-phenyl]-benzenesulfonamide Show/Hide	C22H21N5O2S	1
1	IC50 = 74 nM Bioactivity Info	TI LI LO TS
CP0468081 Compound Info	N-[6-methoxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]acetamide Show/Hide	C31H35N5O3	1
1	IC50 = 75 nM Bioactivity Info	TI LI LO TS
CP0847533 Compound Info	4-(Benzenesulfonylamino-methyl)-cyclohexanecarboxylic acid (1-allyl-6-fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-amide Show/Hide	C27H33FN2O3S	1
1	IC50 = 75 nM Bioactivity Info	TI LI LO TS
CP0500408 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-4-nitrobenzenesulfonamide Show/Hide	C22H19N5O4S	1
1	IC50 = 79 nM Bioactivity Info	TI LI LO TS
CP0535550 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid isoquinolin-5-ylamide Show/Hide	C21H15F3N4O	1
1	IC50 = 80 nM Bioactivity Info	TI LI LO TS
CP0573090 Compound Info	4-(Benzenesulfonylamino-methyl)-cyclohexanecarboxylic acid (7-methoxy-3a,4,5,9b-tetrahydro-1H-benzo[e]indol-2-yl)-amide Show/Hide	C27H33N3O4S	1
1	IC50 = 91 nM Bioactivity Info	TI LI LO TS
CP0448819 Compound Info	N-[4-(5-amino-1-phenylpyrazol-3-yl)phenyl]-4-methoxybenzenesulfonamide Show/Hide	C22H20N4O3S	1
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0460831 Compound Info	4-(Benzenesulfonylamino-methyl)-cyclohexanecarboxylic acid (7-chloro-3a,4,5,9b-tetrahydro-1H-benzo[e]indol-2-yl)-amide Show/Hide	C26H30ClN3O3S	1
1	IC50 = 111 nM Bioactivity Info	TI LI LO TS
CP0535243 Compound Info	4-(Phenylacetylamino-methyl)-cyclohexanecarboxylic acid (6-fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amide Show/Hide	C32H36FN3O2	1
1	IC50 = 114 nM Bioactivity Info	TI LI LO TS
CP0383629 Compound Info	N-[[4-[5-amino-1-[4-(trifluoromethyl)phenyl]pyrazol-3-yl]phenyl]methyl]benzenesulfonamide Show/Hide	C23H19F3N4O2S	1
1	IC50 = 114 nM Bioactivity Info	TI LI LO TS
CP0466849 Compound Info	4-[(2-Fluoro-benzenesulfonylamino)-methyl]-cyclohexanecarboxylic acid (7-methoxy-3a,4,5,9b-tetrahydro-1H-benzo[e]indol-2-yl)-amide Show/Hide	C27H32FN3O4S	1
1	IC50 = 121 nM Bioactivity Info	TI LI LO TS
CP0498062 Compound Info	2-[4-(3-tert-Butyl-ureido)-piperidin-1-yl]-N-(6-fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-acetamide Show/Hide	C28H38FN5O2	1
1	IC50 = 140 nM Bioactivity Info	TI LI LO TS
CP0449226 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-3-(dimethylamino)benzenesulfonamide Show/Hide	C24H25N5O2S	1
1	IC50 = 145 nM Bioactivity Info	TI LI LO TS
CP0510736 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (3,5-dichloro-phenyl)-amide Show/Hide	C18H12Cl2F3N3O	1
1	IC50 = 150 nM Bioactivity Info	TI LI LO TS
CP0453301 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-4-(dimethylamino)benzenesulfonamide Show/Hide	C24H25N5O2S	1
1	IC50 = 162 nM Bioactivity Info	TI LI LO TS
CP0448338 Compound Info	4-[(3-Phenyl-ureido)-methyl]-cyclohexanecarboxylic acid (6-fluoro-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amide Show/Hide	C31H35FN4O2	1
1	IC50 = 170 nM Bioactivity Info	TI LI LO TS
CP0465431 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-2-nitrobenzenesulfonamide Show/Hide	C22H19N5O4S	1
1	IC50 = 178 nM Bioactivity Info	TI LI LO TS
CP0448773 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (5,6,7,8-tetrahydro-naphthalen-1-yl)-amide Show/Hide	C22H20F3N3O	1
1	IC50 = 197 nM Bioactivity Info	TI LI LO TS
CP0391493 Compound Info	(2S)-2-amino-N-(7-fluoro-3a,4,5,9b-tetrahydro-1H-benzo[e]indol-2-yl)-6-[(2-fluorophenyl)sulfonylamino]hexanamide Show/Hide	C24H28F2N4O3S	1
1	IC50 = 202 nM Bioactivity Info	TI LI LO TS
CP0453123 Compound Info	5-Methyl-1-m-tolyl-1H-pyrazole-3-carboxylic acid (3,5-dichloro-phenyl)-amide Show/Hide	C18H15Cl2N3O	1
1	IC50 = 218 nM Bioactivity Info	TI LI LO TS
CP0467873 Compound Info	2-Amino-N-[4-(5-amino-1-p-tolyl-1H-pyrazol-3-yl)-phenyl]-benzenesulfonamide Show/Hide	C22H21N5O2S	1
1	IC50 = 229 nM Bioactivity Info	TI LI LO TS
CP0470890 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid quinolin-5-ylamide Show/Hide	C21H15F3N4O	1
1	IC50 = 232 nM Bioactivity Info	TI LI LO TS
CP0534965 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (2,6-difluoro-phenyl)-amide Show/Hide	C18H12F5N3O	1
1	IC50 = 233 nM Bioactivity Info	TI LI LO TS
CP0476700 Compound Info	N-[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-[4-(phenylcarbamoylamino)piperidin-1-yl]acetamide Show/Hide	C30H34FN5O2	1
1	IC50 = 236 nM Bioactivity Info	TI LI LO TS
CP0460350 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (2-phenylamino-phenyl)-amide Show/Hide	C24H19F3N4O	1
1	IC50 = 267 nM Bioactivity Info	TI LI LO TS
CP0463191 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (2-benzyl-phenyl)-amide Show/Hide	C25H20F3N3O	1
1	IC50 = 292 nM Bioactivity Info	TI LI LO TS
CP0398213 Compound Info	3-Amino-N-[4-(5-amino-1-p-tolyl-1H-pyrazol-3-yl)-phenyl]-benzenesulfonamide Show/Hide	C22H21N5O2S	1
1	IC50 = 303 nM Bioactivity Info	TI LI LO TS
CP0845191 Compound Info	Naphthalene-2-sulfonic acid {4-[(6-methoxy-1-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-methyl]-cyclohexylmethyl}-amide Show/Hide	C35H41N3O3S	1
1	IC50 = 337 nM Bioactivity Info	TI LI LO TS
CP0457334 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid naphthalen-1-ylamide Show/Hide	C22H16F3N3O	1
1	IC50 = 356 nM Bioactivity Info	TI LI LO TS
CP0535332 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (3-bromo-phenyl)-amide Show/Hide	C18H13BrF3N3O	1
1	IC50 = 359 nM Bioactivity Info	TI LI LO TS
CP0397708 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (3-trifluoromethoxy-phenyl)-amide Show/Hide	C19H13F6N3O2	1
1	IC50 = 431 nM Bioactivity Info	TI LI LO TS
CP0465402 Compound Info	N-[4-(5-amino-1-pyridin-2-ylpyrazol-3-yl)phenyl]-4-methoxybenzenesulfonamide Show/Hide	C21H19N5O3S	1
1	IC50 = 436 nM Bioactivity Info	TI LI LO TS
CP0845190 Compound Info	Naphthalene-2-sulfonic acid {4-[(1-benzyl-6-methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-methyl]-cyclohexylmethyl}-amide Show/Hide	C36H42N2O3S	1
1	IC50 = 443 nM Bioactivity Info	TI LI LO TS
CP0475750 Compound Info	4-Dimethylamino-N-[4-(5-methylamino-1-p-tolyl-1H-pyrazol-3-yl)-phenyl]-benzenesulfonamide Show/Hide	C25H27N5O2S	1
1	IC50 = 487 nM Bioactivity Info	TI LI LO TS
CP0457219 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (3-chloro-phenyl)-amide Show/Hide	C18H13ClF3N3O	1
1	IC50 = 520 nM Bioactivity Info	TI LI LO TS
CP0535455 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid o-tolylamide Show/Hide	C19H16F3N3O	1
1	IC50 = 573 nM Bioactivity Info	TI LI LO TS
CP0443899 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid m-tolylamide Show/Hide	C19H16F3N3O	1
1	IC50 = 622 nM Bioactivity Info	TI LI LO TS
CP0510988 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (3-iodo-phenyl)-amide Show/Hide	C18H13F3IN3O	1
1	IC50 = 670 nM Bioactivity Info	TI LI LO TS
CP0451645 Compound Info	3-{5-Amino-3-[4-(4-methoxy-benzenesulfonylamino)-phenyl]-pyrazol-1-yl}-1-trifluoromethyl-pyrazin-1-ium Show/Hide	C21H18F3N6O3S+	1
1	IC50 = 709 nM Bioactivity Info	TI LI LO TS
CP0397654 Compound Info	5-Methyl-1-phenyl-1H-pyrazole-3-carboxylic acid (3,5-dichloro-phenyl)-amide Show/Hide	C17H13Cl2N3O	1
1	IC50 = 759 nM Bioactivity Info	TI LI LO TS
CP0507546 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (2-pyrrol-1-yl-phenyl)-amide Show/Hide	C22H17F3N4O	1
1	IC50 = 763 nM Bioactivity Info	TI LI LO TS
CP0468137 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (4-fluoro-phenyl)-amide Show/Hide	C18H13F4N3O	1
1	IC50 = 800 nM Bioactivity Info	TI LI LO TS
CP0376477 Compound Info	(1-Benzyl-6-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-[2-(3,4-dimethoxy-phenyl)-ethyl]-amine Show/Hide	C28H33NO3	2
1	IC50 = 900 nM Bioactivity Info	TI LI LO TS
2	IC50 ~ 1000 nM Bioactivity Info	TI LI LO TS
CP0466188 Compound Info	N-(7-methoxy-3a,4,5,9b-tetrahydro-1H-benzo[e]indol-2-yl)acetamide Show/Hide	C15H18N2O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0459356 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-4-methoxy-N-methylbenzenesulfonamide Show/Hide	C24H24N4O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0377504 Compound Info	N-[4-[5-amino-1-[4-(trifluoromethyl)pyridin-2-yl]pyrazol-3-yl]phenyl]-4-methoxybenzenesulfonamide Show/Hide	C22H18F3N5O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0395048 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]quinoline-8-sulfonamide Show/Hide	C25H21N5O2S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0496509 Compound Info	N-[4-[5-amino-1-[3,5-bis(trifluoromethyl)phenyl]pyrazol-3-yl]phenyl]-4-methoxybenzenesulfonamide Show/Hide	C24H18F6N4O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0505808 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]naphthalene-1-sulfonamide Show/Hide	C26H22N4O2S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0541541 Compound Info	N-[3-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-4-methoxybenzenesulfonamide Show/Hide	C23H22N4O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0448021 Compound Info	5-Methyl-1-(4-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (3,5-dichloro-phenyl)-amide Show/Hide	C18H12Cl2F3N3O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0448151 Compound Info	1-Benzyl-5-methyl-1H-pyrazole-3-carboxylic acid (3,5-dichloro-phenyl)-amide Show/Hide	C18H15Cl2N3O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0454438 Compound Info	1-(3-Methoxy-phenyl)-5-methyl-1H-pyrazole-3-carboxylic acid (3,5-dichloro-phenyl)-amide Show/Hide	C18H15Cl2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0457016 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (4-chloro-phenyl)-amide Show/Hide	C18H13ClF3N3O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0459311 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid pyridin-2-ylamide Show/Hide	C17H13F3N4O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0486198 Compound Info	5-Methyl-1-(2-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (3,5-dichloro-phenyl)-amide Show/Hide	C18H12Cl2F3N3O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0515173 Compound Info	5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (1H-benzoimidazol-2-yl)-amide Show/Hide	C19H14F3N5O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0535555 Compound Info	5-Methyl-1-thiophen-2-yl-1H-pyrazole-3-carboxylic acid (3,5-dichloro-phenyl)-amide Show/Hide	C15H11Cl2N3OS	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0540292 Compound Info	5-Methyl-1-pyridin-2-yl-1H-pyrazole-3-carboxylic acid (3,5-dichloro-phenyl)-amide Show/Hide	C16H12Cl2N4O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0497953 Compound Info	N-[4-[5-amino-1-(4-methylphenyl)pyrazol-3-yl]phenyl]-4-methoxybenzamide Show/Hide	C24H22N4O2	1
1	IC50 > 3000 nM Bioactivity Info	TI LI LO TS
CP0535153 Compound Info	4-(5-Amino-1-p-tolyl-1H-pyrazol-3-yl)-N-p-tolyl-benzamide Show/Hide	C24H22N4O	1
1	IC50 > 3000 nM Bioactivity Info	TI LI LO TS
CP0067405 Compound Info	3-phenyl-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one Show/Hide	C21H19F3N4O3	1
1	Ki = 0.1585 nM Bioactivity Info	TI LI LO TS
CP0067404 Compound Info	8-[6-(4-fluorophenyl)-1H-benzimidazol-2-yl]-3-phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one Show/Hide	C26H23FN4O2	1
1	Ki = 0.1995 nM Bioactivity Info	TI LI LO TS
CP0067406 Compound Info	3-(4-fluorophenyl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C22H19F4N3O3	1
1	Ki = 0.3162 nM Bioactivity Info	TI LI LO TS
CP0076411 Compound Info	3-phenyl-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C22H20F3N3O3	1
1	Ki = 0.3162 nM Bioactivity Info	TI LI LO TS
CP0124784 Compound Info	2-(2-oxo-3-phenyl-1-oxa-3-azaspiro[4.5]decan-8-yl)-3H-benzimidazole-5-carbonitrile Show/Hide	C22H20N4O2	1
1	Ki = 0.3162 nM Bioactivity Info	TI LI LO TS
CP0473226 Compound Info	2-phenyl-1-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]propan-1-one Show/Hide	C23H24N4OS	1
1	Ki = 0.3981 nM Bioactivity Info	TI LI LO TS
CP0105440 Compound Info	CHEMBL1289609 Show/Hide	C22H21F3N4O3	1
1	Ki = 0.3981 nM Bioactivity Info	TI LI LO TS
CP0372027 Compound Info	N-[[(1R,5S)-3-[(3,5-difluorophenyl)methyl]-3-azabicyclo[3.1.0]hexan-6-yl]methyl]-4-pyridin-2-yl-1,3-thiazol-2-amine Show/Hide	C21H20F2N4S	1
1	Ki = 0.631 nM Bioactivity Info	TI LI LO TS
CP0475668 Compound Info	3-phenyl-1-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]propan-1-one Show/Hide	C23H24N4OS	1
1	Ki = 0.631 nM Bioactivity Info	TI LI LO TS
CP0067409 Compound Info	3-(2-fluorophenyl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C22H19F4N3O3	1
1	Ki = 0.631 nM Bioactivity Info	TI LI LO TS
CP0124787 Compound Info	3-phenyl-8-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C22H20F3N3O2	1
1	Ki = 0.631 nM Bioactivity Info	TI LI LO TS
CP0195878 Compound Info	2-[3-(4-fluorophenyl)-2-oxo-1-oxa-3-azaspiro[4.5]decan-8-yl]-3H-benzimidazole-5-carbonitrile Show/Hide	C22H19FN4O2	1
1	Ki = 0.631 nM Bioactivity Info	TI LI LO TS
CP0501588 Compound Info	(1-phenylcyclopropyl)-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methanone Show/Hide	C24H24N4OS	1
1	Ki = 0.7943 nM Bioactivity Info	TI LI LO TS
CP0523908 Compound Info	[(1S,2S)-2-phenylcyclopropyl]-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methanone Show/Hide	C24H24N4OS	1
1	Ki = 0.7943 nM Bioactivity Info	TI LI LO TS
CP0505937 Compound Info	(3-fluorophenyl)-[(1S,5R)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methanone Show/Hide	C21H19FN4OS	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0518754 Compound Info	2-phenyl-1-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]ethanone Show/Hide	C22H22N4OS	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0523909 Compound Info	2-phenyl-1-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]ethanone Show/Hide	C22H22N4OS	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0453787 Compound Info	N-[[(1S,5R)-3-(1-phenylethyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]-4-pyridin-2-yl-1,3-thiazol-2-amine Show/Hide	C22H24N4S	1
1	Ki = 1.259 nM Bioactivity Info	TI LI LO TS
CP0067408 Compound Info	8-(6-bromo-1H-benzimidazol-2-yl)-3-phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one Show/Hide	C20H19BrN4O2	1
1	Ki = 1.259 nM Bioactivity Info	TI LI LO TS
CP0124786 Compound Info	3-pyridin-2-yl-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C21H19F3N4O3	1
1	Ki = 1.259 nM Bioactivity Info	TI LI LO TS
CP0163144 Compound Info	3-(6-fluoropyridin-2-yl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C21H18F4N4O3	1
1	Ki = 1.259 nM Bioactivity Info	TI LI LO TS
CP0373486 Compound Info	(3,5-difluorophenyl)-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methanone Show/Hide	C21H18F2N4OS	1
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
CP0523907 Compound Info	N-[[(1R,5S)-3-benzyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]-4-pyridin-2-yl-1,3-thiazol-2-amine Show/Hide	C21H22N4S	1
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
CP0067425 Compound Info	3-phenyl-8-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one Show/Hide	C21H19F3N4O2	1
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
CP0105442 Compound Info	2-oxo-3-phenyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)-1-oxa-3,8-diazaspiro[4.5]decane-8-carboxamide Show/Hide	C22H21N5O3S	1
1	Ki = 1.995 nM Bioactivity Info	TI LI LO TS
CP0228722 Compound Info	2-methyl-1-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]propan-1-one Show/Hide	C18H22N4OS	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0541415 Compound Info	phenyl-[(1S,5R)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methanone Show/Hide	C21H20N4OS	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0076414 Compound Info	3-(2-chlorophenyl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C22H19ClF3N3O3	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0401757 Compound Info	N-[[(1S,5R)-3-[(3,5-dimethylphenyl)methyl]-3-azabicyclo[3.1.0]hexan-6-yl]methyl]-4-pyridin-2-yl-1,3-thiazol-2-amine Show/Hide	C23H26N4S	1
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
CP0501586 Compound Info	N-[[(1R,5S)-3-(2-methylpropyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]-4-pyridin-2-yl-1,3-thiazol-2-amine Show/Hide	C18H24N4S	1
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
CP0391433 Compound Info	3-(6-fluoropyridin-2-yl)-8-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C21H18F4N4O2	1
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
CP0383650 Compound Info	oxolan-2-yl-[(1S,5R)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methanone Show/Hide	C19H22N4O2S	1
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0501587 Compound Info	2-methyl-3-phenyl-1-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]butan-1-one Show/Hide	C25H28N4OS	1
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0501589 Compound Info	pyridin-3-yl-[(1S,5R)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methanone Show/Hide	C20H19N5OS	1
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0105439 Compound Info	3-(2-methylphenyl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C23H22F3N3O3	1
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0124788 Compound Info	3-pyridin-2-yl-8-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C21H19F3N4O2	1
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
CP0453789 Compound Info	3-phenyl-1-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]propan-1-one Show/Hide	C23H24N4OS	1
1	Ki = 6.31 nM Bioactivity Info	TI LI LO TS
CP0128717 Compound Info	oxolan-3-yl-[(1S,5R)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methanone Show/Hide	C19H22N4O2S	1
1	Ki = 7.943 nM Bioactivity Info	TI LI LO TS
CP0067407 Compound Info	2-(2-oxo-3-pyridin-2-yl-1-oxa-3-azaspiro[4.5]decan-8-yl)-3H-benzimidazole-5-carbonitrile Show/Hide	C21H19N5O2	1
1	Ki = 7.943 nM Bioactivity Info	TI LI LO TS
CP0389171 Compound Info	(4S)-5-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-5-carbamimidamido-1-[(2S)-2-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-4-carboxybutanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C185H286N52O55S2	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0383651 Compound Info	phenyl-[(1S,5R)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methanone Show/Hide	C21H20N4OS	1
1	Ki = 12.59 nM Bioactivity Info	TI LI LO TS
CP0145327 Compound Info	4-pyridin-2-yl-N-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine Show/Hide	C15H10F3N3S	1
1	Ki = 15.85 nM Bioactivity Info	TI LI LO TS
CP0076410 Compound Info	8-(6-fluoro-1H-benzimidazol-2-yl)-3-phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one Show/Hide	C20H19FN4O2	1
1	Ki = 19.95 nM Bioactivity Info	TI LI LO TS
CP0237115 Compound Info	3-(2-fluoropyridin-3-yl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C21H18F4N4O3	1
1	Ki = 19.95 nM Bioactivity Info	TI LI LO TS
CP0076412 Compound Info	3-pyridin-3-yl-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C21H19F3N4O3	1
1	Ki = 25.12 nM Bioactivity Info	TI LI LO TS
CP0521953 Compound Info	oxan-4-yl-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methanone Show/Hide	C20H24N4O2S	1
1	Ki = 31.62 nM Bioactivity Info	TI LI LO TS
CP0505767 Compound Info	CHEMBL1208795 Show/Hide	C20H19N5OS	1
1	Ki = 50.12 nM Bioactivity Info	TI LI LO TS
CP0270696 Compound Info	3-(2-methylpyridin-3-yl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one Show/Hide	C22H21F3N4O3	1
1	Ki = 79.43 nM Bioactivity Info	TI LI LO TS
CP0405551 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-methyl-1-oxohexan-3-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C181H280N52O55	1
1	Ki = 100 nM Bioactivity Info	TI LI LO TS
CP0405554 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(3S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-1-oxopentan-3-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C180H278N52O55	1
1	Ki = 100 nM Bioactivity Info	TI LI LO TS
CP0124785 Compound Info	8-(1H-benzimidazol-2-yl)-3-phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one Show/Hide	C20H20N4O2	1
1	Ki = 316.23 nM Bioactivity Info	TI LI LO TS
CP0444723 Compound Info	9H-fluoren-9-ylmethyl N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamate Show/Hide	C87H126N26O19	1
1	Ki = 512 nM Bioactivity Info	TI LI LO TS
CP0453788 Compound Info	N-[[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]-4-pyridin-2-yl-1,3-thiazol-2-amine Show/Hide	C14H16N4S	1
1	Ki = 1000 nM Bioactivity Info	TI LI LO TS
CP0392748 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[3-carbamimidamidopropyl-[2-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C180H278N52O55	1
1	Ki = 1000 nM Bioactivity Info	TI LI LO TS
CP0405555 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-6-carbamimidamido-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-1-oxohexan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C181H280N52O55	1
1	Ki = 1000 nM Bioactivity Info	TI LI LO TS
CP0415036 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-3-carbamimidamido-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid Show/Hide	C178H274N52O55	1
1	Ki = 1000 nM Bioactivity Info	TI LI LO TS
CP0505938 Compound Info	1-[(1R,5S)-6-[[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]ethanone Show/Hide	C16H18N4OS	1
1	Ki = 2511.89 nM Bioactivity Info	TI LI LO TS
CP0788275 Compound Info	N-(3-chloro-4-(4-(3-methoxypicolinoyl)piperazin-1-yl)phenyl)-2-methyl-2-phenylpropanamide Hydrochloride salt Show/Hide	C27H30Cl2N4O3	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0269193 Compound Info	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2-aminophenyl)formamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-5-yl)propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-3-carbamoylpropanamido]-4-methylpentanamido]-3-methylbutanamido]-3-hydroxybutanamido]-5-carbamimidamidopentanamido]-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl]pentanediamide Show/Hide	C79H121N27O18	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372192 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl]-2-[(2S)-5-carbamimidamido-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-5-carbamimidamido-2-(phenylformamido)pentanamido]-3-(1H-imidazol-5-yl)propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-3-carbamoylpropanamido]-4-methylpentanamido]-3-methylbutanamido]-3-hydroxybutanamido]pentanamido]pentanediamide Show/Hide	C79H120N26O18	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372194 Compound Info	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(4-aminophenyl)formamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-5-yl)propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-3-carbamoylpropanamido]-4-methylpentanamido]-3-methylbutanamido]-3-hydroxybutanamido]-5-carbamimidamidopentanamido]-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl]pentanediamide Show/Hide	C79H121N27O18	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372195 Compound Info	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(3-aminophenyl)formamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-5-yl)propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-3-carbamoylpropanamido]-4-methylpentanamido]-3-methylbutanamido]-3-hydroxybutanamido]-5-carbamimidamidopentanamido]-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl]pentanediamide Show/Hide	C79H121N27O18	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372196 Compound Info	AcPYY(25-36) Show/Hide	C74H118N26O18	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372197 Compound Info	(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamido-1-hydroxypentylidene]amino]-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino]-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1,4-dihydroxy-4-iminobutylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1-hydroxy-3-methylbutylidene]amino]-1,3-dihydroxybutylidene]amino]-5-carbamimidamido-1-hydroxypentylidene]amino]-N-[(2S)-5-carbamimidamido-1-hydroxy-1-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)-1-iminopropan-2-yl]iminopentan-2-yl]pentanediimidic acid Show/Hide	C72H116N26O17	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372198 Compound Info	AcPYY(22-36) Show/Hide	C86H139N29O22	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372200 Compound Info	AcNPY(25-36) Show/Hide	C76H119N27O18	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0434115 Compound Info	AcPYY(26-36) Show/Hide	C68H106N22O17	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0461743 Compound Info	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(3-aminocyclohexyl)formamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-5-yl)propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-3-carbamoylpropanamido]-4-methylpentanamido]-3-methylbutanamido]-3-hydroxybutanamido]-5-carbamimidamidopentanamido]-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl]pentanediamide Show/Hide	C79H127N27O18	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0461744 Compound Info	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(4-amino-3-methylphenyl)formamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-5-yl)propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-3-carbamoylpropanamido]-4-methylpentanamido]-3-methylbutanamido]-3-hydroxybutanamido]-5-carbamimidamidopentanamido]-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl]pentanediamide Show/Hide	C80H123N27O18	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0464795 Compound Info	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(4-amino-2-chlorophenyl)formamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-5-yl)propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-3-carbamoylpropanamido]-4-methylpentanamido]-3-methylbutanamido]-3-hydroxybutanamido]-5-carbamimidamidopentanamido]-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl]pentanediamide Show/Hide	C79H120ClN27O18	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0471387 Compound Info	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(4-amino-3-methoxyphenyl)formamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-5-yl)propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-3-carbamoylpropanamido]-4-methylpentanamido]-3-methylbutanamido]-3-hydroxybutanamido]-5-carbamimidamidopentanamido]-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl]pentanediamide Show/Hide	C80H123N27O19	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0495808 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl]-2-[(2S)-5-carbamimidamido-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-5-carbamimidamido-2-(2,3-dihydro-1H-indol-2-ylformamido)pentanamido]-3-(1H-imidazol-5-yl)propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-3-carbamoylpropanamido]-4-methylpentanamido]-3-methylbutanamido]-3-hydroxybutanamido]pentanamido]pentanediamide Show/Hide	C81H123N27O18	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0501766 Compound Info	(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]pentanediamide Show/Hide	C84H137N29O21	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0067493 Compound Info	N-[3-chloro-4-[2-(cyclopropylmethyl)-2,8-diazaspiro[4.5]decan-8-yl]phenyl]-2-methyl-2-[4-(trifluoromethyl)pyrimidin-2-yl]propanamide Show/Hide	C27H33ClF3N5O	1
1	Ki > 3981.07 nM Bioactivity Info	TI LI LO TS
CP0388044 Compound Info	N-[4-(4-benzoylpiperazin-1-yl)-3-chlorophenyl]-2,2-dimethylpropanamide Show/Hide	C22H26ClN3O2	1
1	Ki > 5011.87 nM Bioactivity Info	TI LI LO TS

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Prof. Feng ZHU

Prof. Leo, Lianyi Han