| Compound ID |
Compound Name |
Compound Formula |
|
CP0186782
|
(2R,4S)-1-[2-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C23H26ClN3O2S
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0067907
|
(2R,4S)-2-(hydroxymethyl)-1-[2-[4-[[4-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]amino]phenyl]ethyl]piperidin-4-ol
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|
C24H26F3N3O2S
|
1
|
| 1 |
EC50 = 90 nM
|
|
|
|
CP0304537
|
(2R,4S)-2-(hydroxymethyl)-1-[2-[4-[[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]amino]phenyl]ethyl]piperidin-4-ol
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|
C24H29N3O3S
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0215983
|
(2R,4S)-2-(hydroxymethyl)-1-[2-[4-[[4-(3-methylphenyl)-1,3-thiazol-2-yl]amino]phenyl]ethyl]piperidin-4-ol
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|
C24H29N3O2S
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0100910
|
(2R,4S)-2-(hydroxymethyl)-1-[2-[4-[[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]amino]phenyl]ethyl]piperidin-4-ol
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|
C24H26F3N3O2S
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0220533
|
(2R,4S)-1-[2-[4-[[4-[2-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C24H25F4N3O2S
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0078863
|
(2R,4S)-1-[2-[4-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C23H26ClN3O2S
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0233130
|
(2R,4S)-1-[2-[4-[[4-(2-fluorophenyl)-1,3-thiazol-2-yl]amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C23H26FN3O2S
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0199269
|
(2R,4S)-1-[2-[4-[[4-[2-fluoro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C24H25F4N3O2S
|
1
|
| 1 |
EC50 = 250 nM
|
|
|
|
CP0215985
|
(2R,4S)-1-[2-[4-[(4-cyclohexyl-1,3-thiazol-2-yl)amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C23H33N3O2S
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
|
CP0176540
|
(2R,4S)-2-(hydroxymethyl)-1-[2-[4-[(4-phenyl-1,3-thiazol-2-yl)amino]phenyl]ethyl]piperidin-4-ol
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|
C23H27N3O2S
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0176546
|
(2R,4S)-1-[2-[4-[[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C23H25Cl2N3O2S
|
1
|
| 1 |
EC50 = 360 nM
|
|
|
|
CP0186811
|
(2R,4S)-1-[2-[4-[(4-butyl-1,3-thiazol-2-yl)amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C21H31N3O2S
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0176545
|
(2R,4S)-1-[2-[4-[[4-[2-fluoro-5-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C24H25F4N3O2S
|
1
|
| 1 |
EC50 = 390 nM
|
|
|
|
CP0248976
|
(2R,4S)-1-[2-[4-[(4-cyclopentyl-1,3-thiazol-2-yl)amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C22H31N3O2S
|
1
|
| 1 |
EC50 = 850 nM
|
|
|
|
CP0225106
|
(2R,4S)-2-(hydroxymethyl)-1-[2-[4-[[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]amino]phenyl]ethyl]piperidin-4-ol
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|
C24H29N3O3S
|
1
|
| 1 |
EC50 = 870 nM
|
|
|
|
CP0176542
|
(2R,4S)-1-[2-[4-[[4-(4-fluorophenyl)-1,3-thiazol-2-yl]amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C23H26FN3O2S
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0203703
|
(2R,4S)-1-[2-[4-[[4-(3-fluorophenyl)-1,3-thiazol-2-yl]amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C23H26FN3O2S
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0199268
|
(2R,4S)-1-[2-[4-[[4-(1-adamantyl)-1,3-thiazol-2-yl]amino]phenyl]ethyl]-2-(hydroxymethyl)piperidin-4-ol
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|
C27H37N3O2S
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
