| Compound ID |
Compound Name |
Compound Formula |
|
CP0093086
|
quinolinone, 42
Show/Hide
|
C21H15ClF2N4O2
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0398434
|
quinolinone, 43
Show/Hide
|
C22H16ClF2N3O3
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0270646
|
quinolinone, 40
Show/Hide
|
C21H14ClF2N3O2S
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0858282
|
N-(3-Chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-1-methyl-1H-imidazole-5-carboxamide
Show/Hide
|
C20H14ClFN4O2
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0676149
|
N-(3-Chlorophenyl)-N-((7,8-difluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-4-methylnicotinamide
Show/Hide
|
C23H20ClF2N3O2
|
1
|
| 1 |
EC50 = 57 nM
|
|
|
|
CP0270645
|
isoquinoline N-oxide, 47
Show/Hide
|
C21H14ClF2N3O2S
|
1
|
| 1 |
EC50 = 74 nM
|
|
|
|
CP0089375
|
quinolinone, 12
Show/Hide
|
C21H15ClFN3O2S
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0456118
|
quinolinone, 44
Show/Hide
|
C21H14ClF2N3O2S
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0073970
|
4-[(2-cyclobutylimidazo[4,5-b]pyrazin-3-yl)methyl]-7,8-difluoro-1H-quinolin-2-one
Show/Hide
|
C19H15F2N5O
|
1
|
| 1 |
EC50 = 430 nM
|
|
|
|
CP0074303
|
7,8-difluoro-4-[[2-(2-methylpropyl)imidazo[4,5-b]pyrazin-3-yl]methyl]-1H-quinolin-2-one
Show/Hide
|
C19H17F2N5O
|
1
|
| 1 |
EC50 = 440 nM
|
|
|
|
CP0381829
|
isoquinoline N-oxide, 34
Show/Hide
|
C21H15ClFN3O2S
|
1
|
| 1 |
EC50 = 660 nM
|
|
|
|
CP0073971
|
4-[(2-cyclobutylimidazo[4,5-b]pyrazin-3-yl)methyl]-8-fluoro-1H-quinolin-2-one
Show/Hide
|
C19H16FN5O
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0447283
|
4-[[2-cyclobutyl-7-(dimethylamino)imidazo[4,5-b]pyridin-3-yl]methyl]-7,8-difluoro-1H-quinolin-2-one
Show/Hide
|
C22H21F2N5O
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0458775
|
4-[(2-cyclobutylbenzimidazol-1-yl)methyl]-7,8-difluoro-1H-quinolin-2-one
Show/Hide
|
C21H17F2N3O
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0093091
|
quinolinone, 26
Show/Hide
|
C20H18ClFN2O2
|
1
|
| 1 |
EC50 = 2700 nM
|
|
|
|
CP0455362
|
7,8-difluoro-4-[[2-(2-methylpropyl)benzimidazol-1-yl]methyl]-1H-quinolin-2-one
Show/Hide
|
C21H19F2N3O
|
1
|
| 1 |
EC50 = 3100 nM
|
|
|
|
CP0262614
|
4-[[2-(3,3-difluorocyclobutyl)imidazo[4,5-b]pyrazin-3-yl]methyl]-8-fluoro-1H-quinolin-2-one
Show/Hide
|
C19H14F3N5O
|
1
|
| 1 |
EC50 = 3300 nM
|
|
|
|
CP0503135
|
7,8-difluoro-4-[(2-propan-2-ylbenzimidazol-1-yl)methyl]-1H-quinolin-2-one
Show/Hide
|
C20H17F2N3O
|
1
|
| 1 |
EC50 = 4400 nM
|
|
|
|
CP0436568
|
7,8-difluoro-4-[[2-(4-methyl-1,3-thiazol-5-yl)benzimidazol-1-yl]methyl]-1H-quinolin-2-one
Show/Hide
|
C21H14F2N4OS
|
1
|
| 1 |
EC50 = 10300 nM
|
|
|
