Brief Information of the Compound and Protein
Compound Name
4-[[2-(3,3-difluorocyclobutyl)imidazo[4,5-b]pyrazin-3-yl]methyl]-8-fluoro-1H-quinolin-2-one
    Show/Hide
PubChem ID
CID: 49837170
SID: 103912884
Canonical SMILES
Fc1cccc2c(Cn3c(nc4nccnc34)C3CC(F)(F)C3)cc(=O)[nH]c12
    Show/Hide
Compound Formula C19H14F3N5O
Compound Structure
Protein Name
Nitric oxide synthase, inducible
Protein Classification
Enzyme
Uniprot ID
P29477
Gene Name
NOS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 3300 nM
   TI
   LI
   LO
   TS