| Compound ID |
Compound Name |
Compound Formula |
|
CP0011730
|
3,3,3-trifluoro-1-[4-[(1R)-1-[2-[[6-(5-propan-2-yloxypyrimidin-4-yl)-1H-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]propan-1-one
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|
C28H31F3N8O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0014196
|
3,3,3-trifluoro-1-[4-[(1R)-1-[2-[[6-(6-methylpyrimidin-4-yl)-1H-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]propan-1-one
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|
C26H27F3N8O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0014331
|
3,3,3-trifluoro-1-[4-[[2-[[6-[6-(methylamino)pyrimidin-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]methyl]piperazin-1-yl]propan-1-one
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|
C25H26F3N9O
|
1
|
| 1 |
IC50 = 177 nM
|
|
|
|
CP0010821
|
3,3,3-trifluoro-1-[4-[(1R)-1-[2-[[6-[6-(methoxymethyl)pyrimidin-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]propan-1-one
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|
C27H29F3N8O2
|
1
|
| 1 |
IC50 = 192 nM
|
|
|
|
CP0012237
|
1-[4-[(1R)-1-[2-[[6-[6-(dimethylamino)pyrimidin-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]-3,3,3-trifluoropropan-1-one
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|
C27H30F3N9O
|
1
|
| 1 |
IC50 = 276 nM
|
|
|
|
CP0002502
|
1-[4-[(1R)-1-[2-[[6-[1-(cyclobutylmethyl)pyrazol-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]-3,3,3-trifluoropropan-1-one
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|
C29H33F3N8O
|
1
|
| 1 |
IC50 = 325 nM
|
|
|
|
CP0014525
|
3,3,3-trifluoro-1-[4-[[2-[[6-(6-methylpyrimidin-4-yl)-1H-benzimidazol-2-yl]amino]pyridin-4-yl]methyl]piperazin-1-yl]propan-1-one
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|
C25H25F3N8O
|
1
|
| 1 |
IC50 = 434 nM
|
|
|
|
CP0010822
|
1-[4-[[2-[[6-[6-(dimethylamino)pyrimidin-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]methyl]piperazin-1-yl]-3,3,3-trifluoropropan-1-one
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|
C26H28F3N9O
|
1
|
| 1 |
IC50 = 528 nM
|
|
|
|
CP0014195
|
3,3,3-trifluoro-1-[4-[[2-[[6-(2-methylpyridin-4-yl)-1H-benzimidazol-2-yl]amino]pyridin-4-yl]methyl]piperazin-1-yl]propan-1-one
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|
C26H26F3N7O
|
1
|
| 1 |
IC50 = 1060 nM
|
|
|
|
CP0012236
|
1-[4-[(1R)-1-[2-[[6-[6-(cyclopropylmethoxy)pyrimidin-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]-3,3,3-trifluoropropan-1-one
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|
C29H31F3N8O2
|
1
|
| 1 |
IC50 = 1260 nM
|
|
|
|
CP0002500
|
3,3,3-trifluoro-1-[4-[(1R)-1-[2-[[6-(3-methyl-1,2,4-oxadiazol-5-yl)-1H-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]propan-1-one
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|
C24H25F3N8O2
|
1
|
| 1 |
IC50 = 2360 nM
|
|
|
|
CP0012235
|
1-[4-[[2-[[6-[2-(dimethylamino)pyridin-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]methyl]piperazin-1-yl]-3,3,3-trifluoropropan-1-one
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|
C27H29F3N8O
|
1
|
| 1 |
IC50 = 2830 nM
|
|
|
|
CP0004975
|
1-[4-[(1R)-1-[2-[[6-[1-(cyclopropylmethyl)pyrazol-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]-3,3,3-trifluoropropan-1-one
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|
C28H31F3N8O
|
1
|
| 1 |
IC50 = 3220 nM
|
|
|
|
CP0014524
|
1-[4-[[2-[[6-[1-(cyclopropylmethyl)pyrazol-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]methyl]piperazin-1-yl]-3,3,3-trifluoropropan-1-one
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|
C27H29F3N8O
|
1
|
| 1 |
IC50 = 4120 nM
|
|
|
|
CP0003257
|
1-[4-[[2-[[6-[5-chloro-6-(dimethylamino)pyrimidin-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]methyl]piperazin-1-yl]-3,3,3-trifluoropropan-1-one
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|
C26H27ClF3N9O
|
1
|
| 1 |
IC50 = 6110 nM
|
|
|
|
CP0012233
|
1-[4-[[2-[[6-(1-ethylpyrazol-4-yl)-1H-benzimidazol-2-yl]amino]pyridin-4-yl]methyl]piperazin-1-yl]-3,3,3-trifluoropropan-1-one
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|
C25H27F3N8O
|
1
|
| 1 |
IC50 = 8850 nM
|
|
|
|
CP0002499
|
3,3,3-trifluoro-1-[4-[[2-[[6-(3-methyl-1,2,4-oxadiazol-5-yl)-1H-benzimidazol-2-yl]amino]pyridin-4-yl]methyl]piperazin-1-yl]propan-1-one
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|
C23H23F3N8O2
|
1
|
| 1 |
IC50 = 8910 nM
|
|
|
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CP0012259
|
3,3,3-trifluoro-1-[4-[[2-[[6-(1-methylpyrazol-4-yl)-1H-benzimidazol-2-yl]amino]pyridin-4-yl]methyl]piperazin-1-yl]propan-1-one
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|
C24H25F3N8O
|
1
|
| 1 |
IC50 = 11200 nM
|
|
|
