Brief Information of the Cell Line and Protein
Cell Line ID: CL000220 , KB
 Cell Line Info 
Synonyms
KB (HeLa derivative)
HeLa-KB
Strain KB
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0372
Protein ID: PT01651 , Dihydrofolate reductase
 Protein Info 
Gene Name DHFR
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P00374
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000220
 Cell Line Info 
 Protein ID: PT01651
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0036197
 Compound Info 
2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
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C20H22N8O5
  2
1
IC50 = 6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 20 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0036368
 Compound Info 
(2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioic acid
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C20H21N5O6
  2
1
IC50 = 68 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 327 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS