Brief Information of the Cell Line and Protein
Cell Line ID: CL000353 , K562/Adr
 Cell Line Info 
Synonyms
K562/adr
K-562adr
K562adr
K562/ADM
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_3827
Protein ID: PT01546 , ATP-dependent translocase ABCB1
 Protein Info 
Gene Name ABCB1
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID P08183
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000353
 Cell Line Info 
 Protein ID: PT01546
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0484493
 Compound Info 
(2Z,5Z)-3-[3-(diethylamino)propyl]-2-(5-fluoro-2-oxo-1H-indol-3-ylidene)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C28H32FN3O5S
  1
1
Ki = 120 nM
 Bioactivity Info 
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CP0486480
 Compound Info 
(2E,5Z)-3-[3-(diethylamino)propyl]-2-(5-fluoro-2-oxo-1H-indol-3-ylidene)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C28H32FN3O5S
  1
1
Ki = 120 nM
 Bioactivity Info 
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CP0486481
 Compound Info 
(2Z,5Z)-2-(5-chloro-2-oxo-1H-indol-3-ylidene)-3-[3-(diethylamino)propyl]-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C28H32ClN3O5S
  1
1
Ki = 220 nM
 Bioactivity Info 
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CP0538149
 Compound Info 
(2E,5Z)-2-(5-chloro-2-oxo-1H-indol-3-ylidene)-3-[3-(diethylamino)propyl]-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C28H32ClN3O5S
  1
1
Ki = 220 nM
 Bioactivity Info 
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CP0486479
 Compound Info 
(2Z,5Z)-3-[3-(diethylamino)propyl]-2-(5-methyl-2-oxo-1H-indol-3-ylidene)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C29H35N3O5S
  1
1
Ki = 320 nM
 Bioactivity Info 
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CP0538147
 Compound Info 
(2E,5Z)-3-[3-(diethylamino)propyl]-2-(5-methyl-2-oxo-1H-indol-3-ylidene)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C29H35N3O5S
  1
1
Ki = 320 nM
 Bioactivity Info 
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CP0484494
 Compound Info 
(2E,5Z)-3-[3-(diethylamino)propyl]-2-(6-fluoro-2-oxo-1H-indol-3-ylidene)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C28H32FN3O5S
  1
1
Ki = 470 nM
 Bioactivity Info 
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CP0538148
 Compound Info 
(2Z,5Z)-3-[3-(diethylamino)propyl]-2-(6-fluoro-2-oxo-1H-indol-3-ylidene)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one
   Show/Hide
C28H32FN3O5S
  1
1
Ki = 470 nM
 Bioactivity Info 
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CP0453284
 Compound Info 
(2E,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-[3-(diethylamino)propyl]-2-(2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
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C26H27N3O4S
  1
1
Ki = 480 nM
 Bioactivity Info 
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CP0528887
 Compound Info 
(2Z,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-[3-(diethylamino)propyl]-2-(2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
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C26H27N3O4S
  1
1
Ki = 480 nM
 Bioactivity Info 
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CP0528885
 Compound Info 
(2E,5Z)-3-[3-(diethylamino)propyl]-2-(2-oxo-1H-indol-3-ylidene)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C28H33N3O5S
  1
1
Ki = 730 nM
 Bioactivity Info 
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CP0528886
 Compound Info 
(2Z,5Z)-3-[3-(diethylamino)propyl]-2-(2-oxo-1H-indol-3-ylidene)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C28H33N3O5S
  1
1
Ki = 730 nM
 Bioactivity Info 
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CP0486482
 Compound Info 
(2Z,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-[3-(diethylamino)propyl]-2-(5-methyl-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C27H29N3O4S
  1
1
Ki = 940 nM
 Bioactivity Info 
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CP0540207
 Compound Info 
(2E,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-[3-(diethylamino)propyl]-2-(5-methyl-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C27H29N3O4S
  1
1
Ki = 940 nM
 Bioactivity Info 
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CP0453282
 Compound Info 
(2Z,5Z)-3-[3-(diethylamino)propyl]-5-[(2,4-difluorophenyl)methylidene]-2-(6-fluoro-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
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C25H24F3N3O2S
  1
1
Ki = 1010 nM
 Bioactivity Info 
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CP0528884
 Compound Info 
(2E,5Z)-3-[3-(diethylamino)propyl]-5-[(2,4-difluorophenyl)methylidene]-2-(6-fluoro-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
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C25H24F3N3O2S
  1
1
Ki = 1010 nM
 Bioactivity Info 
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CP0380093
 Compound Info 
(2Z,5Z)-3-[2-(dimethylamino)ethyl]-2-(5-fluoro-2-oxo-1H-indol-3-ylidene)-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C22H20FN3O3S
  1
1
Ki = 1340 nM
 Bioactivity Info 
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CP0484495
 Compound Info 
(2E,5Z)-3-[2-(dimethylamino)ethyl]-2-(5-fluoro-2-oxo-1H-indol-3-ylidene)-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C22H20FN3O3S
  1
1
Ki = 1340 nM
 Bioactivity Info 
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CP0484492
 Compound Info 
(2Z,5Z)-3-[3-(diethylamino)propyl]-5-[(2-hydroxyphenyl)methylidene]-2-(5-methyl-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C26H29N3O3S
  1
1
Ki = 1710 nM
 Bioactivity Info 
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CP0486478
 Compound Info 
(2E,5Z)-3-[3-(diethylamino)propyl]-5-[(2-hydroxyphenyl)methylidene]-2-(5-methyl-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C26H29N3O3S
  1
1
Ki = 1710 nM
 Bioactivity Info 
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CP0380094
 Compound Info 
(2Z,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-2-(5-chloro-2-oxo-1H-indol-3-ylidene)-3-[3-(diethylamino)propyl]-1,3-thiazolidin-4-one
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C26H26ClN3O4S
  1
1
Ki = 1780 nM
 Bioactivity Info 
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CP0528889
 Compound Info 
(2E,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-2-(5-chloro-2-oxo-1H-indol-3-ylidene)-3-[3-(diethylamino)propyl]-1,3-thiazolidin-4-one
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C26H26ClN3O4S
  1
1
Ki = 1780 nM
 Bioactivity Info 
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CP0374599
 Compound Info 
(2Z,5Z)-3-[2-(dimethylamino)ethyl]-2-(6-fluoro-2-oxo-1H-indol-3-ylidene)-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C22H20FN3O3S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0395965
 Compound Info 
(2E,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-[2-(dimethylamino)ethyl]-2-(2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
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C23H21N3O4S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0395966
 Compound Info 
(2Z,5Z)-2-(5-chloro-2-oxo-1H-indol-3-ylidene)-3-[3-(diethylamino)propyl]-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C25H26ClN3O3S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0395967
 Compound Info 
(2Z,5Z)-3-[2-(dimethylamino)ethyl]-5-[(4-hydroxyphenyl)methylidene]-2-(5-methyl-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
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C23H23N3O3S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0453283
 Compound Info 
(2E,5Z)-3-[2-(dimethylamino)ethyl]-2-(6-fluoro-2-oxo-1H-indol-3-ylidene)-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one
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C22H20FN3O3S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0471972
 Compound Info 
(2E,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-[3-(diethylamino)propyl]-2-(6-fluoro-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C26H26FN3O4S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0528888
 Compound Info 
(2Z,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-[3-(diethylamino)propyl]-2-(6-fluoro-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C26H26FN3O4S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0528890
 Compound Info 
(2E,5Z)-3-[2-(dimethylamino)ethyl]-5-[(4-hydroxyphenyl)methylidene]-2-(5-methyl-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
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C23H23N3O3S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0538150
 Compound Info 
(2E,5Z)-2-(5-chloro-2-oxo-1H-indol-3-ylidene)-3-[3-(diethylamino)propyl]-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one
   Show/Hide
C25H26ClN3O3S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0538151
 Compound Info 
(2Z,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-[3-(diethylamino)propyl]-2-(5-fluoro-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C26H26FN3O4S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0538152
 Compound Info 
(2E,5Z)-3-[3-(diethylamino)propyl]-5-[(3,4-difluorophenyl)methylidene]-2-(5-fluoro-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C25H24F3N3O2S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0538153
 Compound Info 
(2Z,5Z)-3-[3-(diethylamino)propyl]-5-[(3,4-difluorophenyl)methylidene]-2-(5-fluoro-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C25H24F3N3O2S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0539345
 Compound Info 
(2E,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-[3-(diethylamino)propyl]-2-(5-fluoro-2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
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C26H26FN3O4S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0540205
 Compound Info 
(2Z,5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-[2-(dimethylamino)ethyl]-2-(2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C23H21N3O4S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0540206
 Compound Info 
(2Z,5Z)-3-[2-(dimethylamino)ethyl]-5-[(4-hydroxyphenyl)methylidene]-2-(2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C22H21N3O3S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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CP0540605
 Compound Info 
(2E,5Z)-3-[2-(dimethylamino)ethyl]-5-[(4-hydroxyphenyl)methylidene]-2-(2-oxo-1H-indol-3-ylidene)-1,3-thiazolidin-4-one
   Show/Hide
C22H21N3O3S
  1
1
Ki > 2230 nM
 Bioactivity Info 
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