Compound ID |
Compound Name |
Compound Formula |
CP0576839
|
4-[(1S)-1-[[2-[(4-methylphenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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C25H25NO4S
|
1
|
1 |
IC50 = 0.4 nM
|
|
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CP0569366
|
4-[(1S)-1-[[2-[(4-chlorophenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C24H22ClNO4S
|
1
|
1 |
IC50 = 1 nM
|
|
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CP0579483
|
4-[1-[[2-[[3-(trifluoromethyl)phenyl]methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]cyclopropyl]benzoic acid
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|
C26H22F3NO4S
|
1
|
1 |
IC50 = 1 nM
|
|
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CP0564321
|
4-[(1S)-1-[[2-[[3-(trifluoromethyl)phenyl]methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C25H22F3NO4S
|
1
|
1 |
IC50 = 1.7 nM
|
|
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CP0552065
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4-[(1S)-1-[[2-[(3-fluoro-4-methoxyphenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C25H24FNO5S
|
1
|
1 |
IC50 = 1.9 nM
|
|
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CP0564322
|
4-[(1S)-1-[[2-[(3-methoxyphenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C25H25NO5S
|
1
|
1 |
IC50 = 1.9 nM
|
|
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CP0550439
|
4-[(1S)-1-[[2-[(4-methoxyphenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C25H25NO5S
|
1
|
1 |
IC50 = 2.1 nM
|
|
|
CP0575940
|
4-[(1S)-1-[[2-[[4-(trifluoromethyl)phenyl]methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C25H22F3NO4S
|
1
|
1 |
IC50 = 2.1 nM
|
|
|
CP0452755
|
4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}-carbonyl)amino]cyclopropyl}benzoic Acid
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|
C25H22F3NO3S
|
1
|
1 |
IC50 = 2.5 nM
|
|
|
CP0579647
|
4-[(1S)-1-[[2-[(2,4-dichloro-5-fluorophenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C24H20Cl2FNO4S
|
1
|
1 |
IC50 = 2.5 nM
|
|
|
CP0568147
|
4-[(1S)-1-[[2-[(4-propan-2-ylphenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C27H29NO4S
|
1
|
1 |
IC50 = 2.7 nM
|
|
|
CP0568146
|
4-[(1S)-1-[[2-[(3-chlorophenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C24H22ClNO4S
|
1
|
1 |
IC50 = 3.2 nM
|
|
|
CP0569367
|
4-[1-[[2-[(4-fluorophenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]cyclopropyl]benzoic acid
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|
C25H22FNO4S
|
1
|
1 |
IC50 = 3.4 nM
|
|
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CP0570161
|
4-[[[2-[[3-(trifluoromethyl)phenyl]methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]methyl]benzoic acid
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|
C24H20F3NO4S
|
1
|
1 |
IC50 = 3.4 nM
|
|
|
CP0569215
|
4-[[[2-[(4-fluorophenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]methyl]benzoic acid
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|
C23H20FNO4S
|
1
|
1 |
IC50 = 4.3 nM
|
|
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CP0578933
|
4-[(1S)-1-[[2-[(4-fluorophenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C24H22FNO4S
|
1
|
1 |
IC50 = 4.5 nM
|
|
|
CP0579924
|
4-[(1S)-1-[[2-[(3-fluorophenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C24H22FNO4S
|
1
|
1 |
IC50 = 5.1 nM
|
|
|
CP0576838
|
4-[(1S)-1-[[2-[[3-chloro-4-(trifluoromethoxy)phenyl]methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C25H21ClF3NO5S
|
1
|
1 |
IC50 = 6.6 nM
|
|
|
CP0435681
|
US8686018, 107
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|
C22H18F5N3O4
|
1
|
1 |
IC50 = 7.5 nM
|
|
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CP0564324
|
4-[(1S)-1-[[2-[(4-tert-butylphenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C28H31NO4S
|
1
|
1 |
IC50 = 9.5 nM
|
|
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CP0576837
|
4-[(1S)-1-[[2-[2-(4-fluorophenyl)ethyl]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carbonyl]amino]ethyl]benzoic acid
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|
C25H24FNO3S
|
1
|
1 |
IC50 = 10.3 nM
|
|
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CP0564320
|
4-[(1S)-1-[[2-[2-(3-methoxyphenyl)ethynyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C26H23NO5S
|
1
|
1 |
IC50 = 12.4 nM
|
|
|
CP0564319
|
4-[(1S)-1-[[2-[2-(4-fluorophenyl)ethyl]-6,7-dihydro-4H-thieno[3,2-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C25H24FNO4S
|
1
|
1 |
IC50 = 13.1 nM
|
|
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CP0570157
|
4-[(1S)-1-[[2-[2-(4-fluorophenyl)ethynyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
Show/Hide
|
C25H20FNO4S
|
1
|
1 |
IC50 = 15.8 nM
|
|
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CP0569739
|
4-[(1S)-1-[[2-[2-(4-fluorophenyl)ethyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C25H24FNO4S
|
1
|
1 |
IC50 = 19.1 nM
|
|
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CP0580247
|
4-[(1S)-1-[[2-[2-(6-methoxynaphthalen-2-yl)ethynyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C30H25NO5S
|
1
|
1 |
IC50 = 27.2 nM
|
|
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CP0564330
|
4-[(1S)-1-[[2-[2-(4-fluorophenyl)ethyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonyl]amino]ethyl]benzoic acid
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|
C26H26FNO3S
|
1
|
1 |
IC50 = 27.8 nM
|
|
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CP0569368
|
4-[[[2-[(4-fluorophenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]methyl]cyclohexane-1-carboxylic acid
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|
C23H26FNO4S
|
1
|
1 |
IC50 = 30.3 nM
|
|
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CP0564380
|
4-[(1S)-1-[[2-[[4-(trifluoromethyl)phenyl]methylamino]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C25H23F3N2O4S
|
1
|
1 |
IC50 = 32.9 nM
|
|
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CP0579246
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4-[(1S)-1-[[2-[2-(4-fluorophenyl)ethyl]-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C27H28FNO4S
|
1
|
1 |
IC50 = 36.2 nM
|
|
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CP0570162
|
4-[[[2-[[3-(trifluoromethyl)phenyl]methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]methyl]cyclohexane-1-carboxylic acid
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|
C24H26F3NO4S
|
1
|
1 |
IC50 = 36.6 nM
|
|
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CP0564325
|
2-[(4-fluorophenyl)methyl]-N-[(1S)-1-[4-(hydrazinecarbonyl)phenyl]ethyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
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|
C24H24FN3O3S
|
1
|
1 |
IC50 = 74.9 nM
|
|
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CP0578379
|
2-[(4-fluorophenyl)methyl]-N-[(1S)-1-[4-[methoxy(methyl)carbamoyl]phenyl]ethyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
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|
C26H27FN2O4S
|
1
|
1 |
IC50 = 186.9 nM
|
|
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CP0578918
|
4-[(1S)-1-[[2-[2-(4-fluorophenyl)ethyl]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonyl]amino]ethyl]benzoic acid
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|
C27H28FNO3S
|
1
|
1 |
IC50 = 205.5 nM
|
|
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CP0580216
|
4-[(1S)-1-[[2-[2-(4-fluorophenyl)ethyl]-6-[(2-methylpropan-2-yl)oxycarbonyl]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carbonyl]amino]ethyl]benzoic acid
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|
C30H33FN2O5S
|
1
|
1 |
IC50 = 315 nM
|
|
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CP0575939
|
4-[(1S)-1-[[2-[2-(6-oxo-1H-pyridin-3-yl)ethynyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C24H20N2O5S
|
1
|
1 |
IC50 = 642.3 nM
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|
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CP0579482
|
4-[(1S)-1-[[6-ethyl-2-[2-(4-fluorophenyl)ethyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonyl]amino]ethyl]benzoic acid
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|
C28H30FNO3S
|
1
|
1 |
IC50 = 648.5 nM
|
|
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CP0579925
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4-[(1R)-1-[[2-[(4-fluorophenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C24H22FNO4S
|
1
|
1 |
IC50 = 786.1 nM
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|
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CP0543689
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3-[[[2-[[3-(trifluoromethyl)phenyl]methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]methyl]benzoic acid
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|
C24H20F3NO4S
|
1
|
1 |
IC50 > 1000 nM
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|
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CP0579247
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4-[(1S)-1-[[6-acetyl-2-[2-(4-fluorophenyl)ethyl]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carbonyl]amino]ethyl]benzoic acid
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|
C27H27FN2O4S
|
1
|
1 |
IC50 > 1000 nM
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CP0579291
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methyl 4-[(1S)-1-[[2-[(4-fluorophenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoate
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|
C25H24FNO4S
|
1
|
1 |
IC50 > 1000 nM
|
|
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CP0580179
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4-[(1S)-1-[[2-[(4-fluorobenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C24H21FN2O5S
|
1
|
1 |
IC50 > 1000 nM
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CP0580231
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4-[(1S)-1-[[2-[(E)-[3-(trifluoromethyl)phenyl]methylideneamino]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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|
C25H21F3N2O4S
|
1
|
1 |
IC50 > 1000 nM
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