Brief Information of the Cell Line and Protein
Cell Line ID: CL000596 , U266B1
Synonyms
U266-B1
U266 B1
U-266
U 266
U266
U266S
U266BL
U266 Bl
266 Bl
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0566
Protein ID: PT01503 , Signal transducer and activator of transcription 3
Gene Name STAT3
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P40763
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000596  Protein ID: PT01503
 
Compound ID Compound Name Compound Formula
CP0431542
Benzyl 1-(4-Cyano-2,3,5,6-tetrafluorophenyl)-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
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C24H9F7N2O3
 1
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
CP0209354
ethyl 1-(4-cyano-2,3,5,6-tetrafluorophenyl)-6,7,8-trifluoro-4-oxoquinoline-3-carboxylate
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C19H7F7N2O3
 1
1
EC50 = 170 nM
   TI
   LI
   LO
   TS
CP0431541
1-(4-Cyano-2,3,5,6-tetrafluorophenyl)-6,7,8-trifluoro-N-(4-fluorobenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
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C24H9F8N3O2
 1
1
EC50 = 200 nM
   TI
   LI
   LO
   TS
CP0461408
ethyl 5,6,7,8-tetrafluoro-4-oxo-1-(2,3,4,5,6-pentafluorophenyl)quinoline-3-carboxylate
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C18H6F9NO3
 1
1
EC50 = 4600 nM
   TI
   LI
   LO
   TS
CP0504307
5,6,7,8-Tetrafluoro-4-oxo-1-(pentafluoro-phenyl)-1,4-dihydroquinoline-3-carboxylic acid
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C16H2F9NO3
 1
1
EC50 = 46000 nM
   TI
   LI
   LO
   TS