Brief Information of the Cell Line and Protein
Cell Line ID: CL000460 , Flp-In-T-REx-293
 Cell Line Info 
Synonyms
Flp-In-T-REx 293
Flp-In T-REx-293
Flp-In T-REx 293
Flp-In T-Rex HEK293
Flp-In 293 T-Rex
Flp-In-T-REx
293-Flip-in-TRex
HEK293 Flp-In T-REx
HEK293FlpIN
293FlpIn T-Rex
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_U427
Protein ID: PT01491 , Metabotropic glutamate receptor 2
 Protein Info 
Gene Name GRM2
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P31421
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000460
 Cell Line Info 
 Protein ID: PT01491
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0426559
 Compound Info 
(2S)-2-[[4-(2,3-dimethylphenyl)phenoxy]methyl]-5-methyl-2,3-dihydro-[1,3]oxazolo[3,2-a]pyrimidin-7-one
   Show/Hide
C22H22N2O3
  1
1
EC50 = 10.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0426536
 Compound Info 
(2S)-2-[[4-(2,3-dimethylphenyl)phenoxy]methyl]-6-ethyl-2,3-dihydro-[1,3]oxazolo[3,2-a]pyrimidin-7-one
   Show/Hide
C23H24N2O3
  1
1
EC50 = 20.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0392577
 Compound Info 
(2S)-2-[[4-(2,3-dimethylphenyl)phenoxy]methyl]-2,3-dihydro-[1,3]oxazolo[3,2-a]pyrimidin-7-one
   Show/Hide
C21H20N2O3
  1
1
EC50 = 29.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0389393
 Compound Info 
(2S)-2-[[4-[3-(trifluoromethyl)phenyl]phenoxy]methyl]-2,3-dihydro-[1,3]oxazolo[3,2-a]pyrimidin-7-one
   Show/Hide
C20H15F3N2O3
  1
1
EC50 = 79.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0434655
 Compound Info 
(2S)-2-[(1,1-dimethyl-2,3-dihydroinden-5-yl)oxymethyl]-2,3-dihydro-[1,3]oxazolo[3,2-a]pyrimidin-7-one
   Show/Hide
C18H20N2O3
  1
1
EC50 = 250 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0389392
 Compound Info 
(2S)-2-[(4-tert-butylphenoxy)methyl]-2,3-dihydro-[1,3]oxazolo[3,2-a]pyrimidin-7-one
   Show/Hide
C17H20N2O3
  1
1
EC50 = 314 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS