Brief Information of the Cell Line and Protein
Cell Line ID: CL000392 , Y1
 Cell Line Info 
Synonyms
Y-1
Y 1
Clone Y-1
Clone Y1
GM05384
Category Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0585
Protein ID: PT01431 , Melanocortin receptor 4
 Protein Info 
Gene Name MC4R
Organism Mus musculus, Mouse
Protein Classification Membrane receptor
Uniprot ID P56450
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000392
 Cell Line Info 
 Protein ID: PT01431
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0149367
 Compound Info 
(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide
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C33H41ClN6O2
  1
1
EC50 = 7.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0045108
 Compound Info 
(4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S)-6-amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl]carbamoyl}-4-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]butanoic acid
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C77H109N21O19S
  1
1
EC50 = 8.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393281
 Compound Info 
(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-4-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide
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C32H34ClN7O2
  1
1
EC50 = 38 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0269557
 Compound Info 
(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-1-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide
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C32H34ClN7O2
  1
1
EC50 = 59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS