Brief Information of the Cell Line and Protein
Cell Line ID: CL000273 , Hep 3B2.1-7
 Cell Line Info 
Synonyms
Hep 3B2_1-7
HEP3B217
Hep 3B2
HEP-3B2
HEP3B2
Hep-3B
HEP-3B
Hep 3B
Hep3B
HEP3B
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0326
Protein ID: PT01286 , Bile acid receptor
 Protein Info 
Gene Name NR1H4
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID Q96RI1
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000273
 Cell Line Info 
 Protein ID: PT01286
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0556636
 Compound Info 
3-[(1S)-1-(6-chloro-1-methylbenzimidazol-2-yl)-2-[1-(2-methylpropanoyl)piperidin-4-yl]ethyl]-1-(4-phenoxyphenyl)imidazolidine-2,4-dione
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C34H36ClN5O4
  1
1
IC50 = 0.05 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0561829
 Compound Info 
3-[(1S)-1-(5-fluoro-1-methylbenzimidazol-2-yl)-2-[1-(2-methylpropanoyl)piperidin-4-yl]ethyl]-1-(4-phenoxyphenyl)imidazolidine-2,4-dione
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C34H36FN5O4
  1
1
IC50 = 0.06 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0364655
 Compound Info 
3-[(1S)-2-(1-acetylpiperidin-4-yl)-1-(1,6-dimethylbenzimidazol-2-yl)ethyl]-1-(4-phenoxyphenyl)imidazolidine-2,4-dione
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C33H35N5O4
  1
1
IC50 = 0.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0489955
 Compound Info 
3-[(1S)-2-(1-acetylpiperidin-4-yl)-1-(6-chloro-1-methylbenzimidazol-2-yl)ethyl]-1-(4-phenoxyphenyl)imidazolidine-2,4-dione
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C32H32ClN5O4
  1
1
IC50 = 0.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0537010
 Compound Info 
3-[(1S)-2-(1-acetylpiperidin-4-yl)-1-(5-fluoro-1-methylbenzimidazol-2-yl)ethyl]-1-(4-phenoxyphenyl)imidazolidine-2,4-dione
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C32H32FN5O4
  1
1
IC50 = 1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0224620
 Compound Info 
3-[(1S)-1-(1,6-dimethylbenzimidazol-2-yl)-2-piperidin-4-ylethyl]-1-(4-phenoxyphenyl)imidazolidine-2,4-dione
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C31H33N5O3
  1
1
IC50 = 4510 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0354505
 Compound Info 
3-[(1S)-1-(1,6-dimethylbenzimidazol-2-yl)-2-[1-(2-methylpropyl)piperidin-4-yl]ethyl]-1-(4-phenoxyphenyl)imidazolidine-2,4-dione
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C35H41N5O3
  1
1
IC50 = 17400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS