| Compound ID |
Compound Name |
Compound Formula |
|
CP0375046
|
[1-[(1-hydroxy-2-oxoazepan-3-yl)amino]-2-methyl-1-oxotetradecan-3-yl] 6-[acetyl(hydroxy)amino]-2-[[2-(2-hydroxyphenyl)-1,3-oxazole-4-carbonyl]amino]hexanoate
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|
C39H59N5O10
|
2
|
| 1 |
IC50 = 630 nM
|
|
|
| 2 |
Ki = 130 nM
|
|
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CP0494602
|
[1-[(1-hydroxy-2-oxoazepan-3-yl)amino]-2-methyl-1-oxohexadecan-3-yl] 6-[acetyl(hydroxy)amino]-2-[[2-(2-hydroxyphenyl)-1,3-oxazole-4-carbonyl]amino]hexanoate
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|
C41H63N5O10
|
2
|
| 1 |
IC50 = 1100 nM
|
|
|
| 2 |
Ki = 230 nM
|
|
|
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CP0496084
|
[2-methyl-1-oxo-1-[(2-oxoazepan-3-yl)amino]hexadecan-3-yl] 6-[acetyl(hydroxy)amino]-2-[[2-(2-hydroxyphenyl)-1,3-oxazole-4-carbonyl]amino]hexanoate
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|
C41H63N5O9
|
2
|
| 1 |
IC50 = 4560 nM
|
|
|
| 2 |
Ki = 970 nM
|
|
|
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CP0447192
|
[2-methyl-1-oxo-1-[(2-oxoazepan-3-yl)amino]tetradecan-3-yl] 6-[acetyl(hydroxy)amino]-2-[[2-(2-hydroxyphenyl)-1,3-oxazole-4-carbonyl]amino]hexanoate
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|
C39H59N5O9
|
2
|
| 1 |
IC50 = 4700 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
|
|
CP0496083
|
[1-[(1-hydroxy-2-oxoazepan-3-yl)amino]-2-methyl-1-oxododecan-3-yl] 6-[acetyl(hydroxy)amino]-2-[[2-(2-hydroxyphenyl)-1,3-oxazole-4-carbonyl]amino]hexanoate
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|
C37H55N5O10
|
2
|
| 1 |
IC50 = 5890 nM
|
|
|
| 2 |
Ki = 1250 nM
|
|
|
|
CP0496082
|
[1-[(1-hydroxy-2-oxoazepan-3-yl)amino]-2-methyl-1-oxooctadecan-3-yl] 6-[acetyl(hydroxy)amino]-2-[[2-(2-hydroxyphenyl)-1,3-oxazole-4-carbonyl]amino]hexanoate
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|
C43H67N5O10
|
2
|
| 1 |
IC50 = 6290 nM
|
|
|
| 2 |
Ki = 1330 nM
|
|
|
|
CP0421919
|
3-(cyclohexylmethyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C18H27NO2
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0444975
|
3-((4-methoxyphenethylamino)methyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C21H28N2O3
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0458615
|
2-phenyl-N-((3-(piperidin-1-yl)-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-yl)methyl)ethanamine
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|
C23H30N2O2
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0467970
|
2-phenyl-N-((3-(pyrrolidin-1-yl)-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-yl)methyl)ethanamine
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|
C22H28N2O2
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0485539
|
3-(4-cyclohexylbutyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C21H33NO2
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0496806
|
N,N-dimethyl-3-[[methyl(2-phenylethyl)amino]methyl]-2,4-dihydro-1,5-benzodioxepin-3-amine
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|
C21H28N2O2
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0466856
|
7,8-dichloro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyran-4-yl)ethylamino)methyl)-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C19H28Cl2N2O3
|
1
|
| 1 |
Ki = 0.22 nM
|
|
|
|
CP0062485
|
4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester
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|
C22H31NO3
|
1
|
| 1 |
Ki = 0.78 nM
|
|
|
|
CP0505615
|
3-[[2-(1-adamantyl)ethylamino]methyl]-N,N-dimethyl-2,4-dihydro-1,5-benzodioxepin-3-amine
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|
C24H36N2O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
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CP0421914
|
(4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-yl)methylamino)ethyl)cyclohexyl)methanol
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|
C21H34N2O3
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
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CP0425660
|
3-((2-cyclohexylethylamino)methyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C20H32N2O2
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
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CP0501809
|
3-((2-cycloheptylethylamino)methyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C21H34N2O2
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
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CP0485540
|
4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-yl)methylamino)ethyl)cyclohexanol
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|
C20H32N2O3
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
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CP0524517
|
3-((2-cyclopentylethylamino)methyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C19H30N2O2
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
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CP0461474
|
7-fluoro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyran-4-yl)ethylamino)methyl)-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C19H29FN2O3
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
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CP0485512
|
3-((cyclohexylmethylamino)methyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C19H30N2O2
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
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CP0466854
|
3-((2-(3,6-dihydro-2H-thiopyran-4-yl)ethylamino)methyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C19H28N2O2S
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
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CP0485536
|
N,N-dimethyl-3-[[2-(thian-4-yl)ethylamino]methyl]-2,4-dihydro-1,5-benzodioxepin-3-amine
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|
C19H30N2O2S
|
1
|
| 1 |
Ki = 6.8 nM
|
|
|
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CP0524516
|
N,N-dimethyl-3-[[2-(oxan-4-yl)ethylamino]methyl]-2,4-dihydro-1,5-benzodioxepin-3-amine
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|
C19H30N2O3
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0509444
|
N,N-dimethyl-3-[[2-(oxan-4-ylidene)ethylamino]methyl]-2,4-dihydro-1,5-benzodioxepin-3-amine
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|
C19H28N2O3
|
1
|
| 1 |
Ki = 14 nM
|
|
|
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CP0424219
|
N,N-dimethyl-3-[[2-(4-methylphenyl)ethylamino]methyl]-2,4-dihydro-1,5-benzodioxepin-3-amine
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|
C21H28N2O2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
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CP0458616
|
3-((2-fluorophenethylamino)methyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C20H25FN2O2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
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CP0421962
|
N,N-dimethyl-3-[(2-phenylethylamino)methyl]-2,4-dihydro-1,5-benzodioxepin-3-amine
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|
C20H26N2O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0444976
|
3-((4-chlorophenethylamino)methyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C20H25ClN2O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
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CP0458618
|
3-((2,6-dichlorophenethylamino)methyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C20H24Cl2N2O2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
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CP0421918
|
3-((4-isopropylphenethylamino)methyl)-N,N-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine
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|
C23H32N2O2
|
1
|
| 1 |
Ki = 56 nM
|
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