Brief Information of the Cell Line and Protein
Cell Line ID: CL000064 , Chem-1
 Cell Line Info 
Synonyms
ChemiSCREEN Chem-1
Wild-type control Chem-1 cell line
ChemiSCREEN Chem-1 parental cell line
Category Undefined cell line type
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_L474
Protein ID: PT01205 , Prostaglandin E2 receptor EP1 subtype
 Protein Info 
Gene Name PTGER1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P34995
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000064
 Cell Line Info 
 Protein ID: PT01205
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0055947
 Compound Info 
(15S)-prostaglandin E2
   Show/Hide
C20H32O5
  1
1
IC50 < 30 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0168917
 Compound Info 
Omidenepag
   Show/Hide
C23H22N6O4S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440482
 Compound Info 
De-117
   Show/Hide
C26H28N6O4S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0179414
 Compound Info 
3-(2-((E)-3-(4-(benzyloxy)-3-methoxyphenyl)prop-1-enyl)phenyl)-N-(thiophen-2-ylsulfonyl)acrylamide
   Show/Hide
C30H27NO5S2
  1
1
Ki = 2443 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0058712
 Compound Info 
N-[5-(2,6-dichlorophenyl)-1,3,4-thiadiazol-2-yl]-4-ethyl-2,3-dihydro-1,4-benzoxazine-6-carboxamide
   Show/Hide
C19H16Cl2N4O2S
  1
1
Ki > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380092
 Compound Info 
N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-4-ethyl-2,3-dihydro-1,4-benzoxazine-6-carboxamide
   Show/Hide
C16H18N4O2S
  1
1
Ki > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0397467
 Compound Info 
(E)-3-[2-[(E)-3-[4-[2-(1-cyanoisoindol-2-yl)ethoxy]-3-methoxyphenyl]prop-1-enyl]phenyl]prop-2-enoic acid
   Show/Hide
C30H26N2O4
  1
1
Ki = 15990 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0314860
 Compound Info 
(E)-3-[2-[(E)-3-[4-[2-(1-cyanoisoindol-2-yl)ethoxy]-3-methoxyphenyl]prop-1-enyl]phenyl]-N-thiophen-2-ylsulfonylprop-2-enamide
   Show/Hide
C34H29N3O5S2
  1
1
Ki = 20260 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0857864
 Compound Info 
1-(2-(4-((E)-3-(2-((E)-2-Carboxyvinyl)phenyl)allyl)-2-methoxyphenoxy)ethyl)-4-((1E,3E)-4-(4-(dimethylamino)phenyl)buta-1,3-dienyl)-2,6-dimethylpyridinium boron tetrafluoride
   Show/Hide
C40H43BF4N2O4
  1
1
Ki = 68625 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS