| Compound ID |
Compound Name |
Compound Formula |
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CP0659262
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(1S,2S,3R,4R)-3-{6-Chloro-2-[2-methoxy-4-(4-morpholin-4-yl-piperidin-1-yl)-phenyl]-3H-imidazo[4,5-b]pyridin-7-ylamino}-bicyclo[2.2.1]hept-5-ene-2-carboxylicacidamide
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C30H36ClN7O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
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CP0704533
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(1S,2S,3R,4R)-3-{6-Chloro-2-[2-methoxy-4-(4-methyl-piperazin-1-yl)-phenyl]-3Himidazo[4,5-b]pyridin-7-ylamino}-bicyclo[2.2.1]hept-5-ene-2-carboxylic
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C26H30ClN7O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
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CP0842622
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(1S,2S,3R,4R)-3-{6-Chloro-2-[2-methoxy-4-(4-methyl-piperazin-1-ylmethyl)-phenyl]-3H-imidazo[4,5-b]pyridin-7-ylamino}-bicyclo[2.2.1]hept-5-ene-2-carboxylicacidamide
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|
C27H32ClN7O2
|
1
|
| 1 |
IC50 = 8 nM
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|
|
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CP0078581
|
N-[6-chloro-19-methoxy-17-(4-methylpiperazin-1-yl)-2,4,8,22-tetrazatetracyclo[14.3.1.13,7.19,13]docosa-1(19),3,5,7(22),9,11,13(21),16(20),17-nonaen-10-yl]-N-methylmethanesulfonamide
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|
C26H32ClN7O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
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CP0762036
|
(1S,2S,3R,4R)-3-(6-Chloro-2-{2-methoxy-4-[4-(4-methyl-piperazin-1-yl)-piperidin-1-yl]-phenyl}-3H-imidazo[4,5-b]pyridin-7-ylamino)-bicyclo[2.2.1]hept-5-ene-2-carboxylicacidamide
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|
C31H39ClN8O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
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CP0071455
|
2-[4-[2-[[5-chloro-4-(2-pyrazol-1-ylanilino)pyrimidin-2-yl]amino]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-6-yl]piperazin-1-yl]ethanol
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|
C31H37ClN8O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
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CP0089290
|
(1S,2S,3R,4R)-3-[[5-chloro-2-[[(7S)-4-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
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|
C28H35ClN6O3
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1
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| 1 |
IC50 = 20 nM
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|
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CP0059911
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2-[[5-chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C30H38ClN7O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
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CP0110196
|
6-chloro-19-methoxy-17-(4-methylpiperazin-1-yl)-10-propan-2-ylsulfonyl-2,4,8,22-tetrazatetracyclo[14.3.1.13,7.19,13]docosa-1(19),3,5,7(22),9,11,13(21),16(20),17-nonaene
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|
C27H33ClN6O3S
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
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CP0769733
|
(1S,2S,3R,4R)-3-{6-Chloro-2-[4-(4-methyl-piperazin-1-yl)-phenyl]-3H-imidazo[4,5-b]pyridin-7-ylamino}-bicyclo[2.2.1]hept-5-ene-2-carboxylicacidamide
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|
C25H28ClN7O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
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CP0046482
|
(1S,2S,3R,4R)-3-[[5-chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
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|
C30H40ClN7O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
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CP0555827
|
N-[2-[[5-chloro-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]phenyl]-N-methylmethanesulfonamide
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|
C30H40ClN7O4S
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
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CP0659259
|
(1S,2S,3R,4R)-3-{6-Bromo-2-[4-(4-methyl-piperazin-1-yl)-phenyl]-3H-imidazo[4,5-b]pyridin-7-ylamino}-bicyclo[2.2.1]hept-5-ene-2-carboxylicacidamide
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|
C25H28BrN7O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
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CP0769350
|
(1S,2S,3R,4R)-3-[6-Chloro-2-(2-methoxy-4-morpholin-4-yl-phenyl)-3H-imidazo[4,5-b]pyridin-7-ylamino]-bicyclo[2.2.1]hept-5-ene-2-carboxylicacidamide
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|
C25H27ClN6O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
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CP0091557
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2-[[5-chloro-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]-N,N-dimethylbenzenesulfonamide
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|
C30H40ClN7O4S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
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CP0191549
|
2-[[5-chloro-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C30H38ClN7O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
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CP0398360
|
N-[2-[[5-chloro-2-[[1-methoxy-6-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]phenyl]-N-methylmethanesulfonamide
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|
C29H38ClN7O3S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
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CP0091556
|
(1S,2S,3R,4R)-3-[[5-chloro-2-[[(6R)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
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|
C30H40ClN7O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
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CP0294241
|
2-[[5-chloro-2-[[(6R)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C30H38ClN7O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
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CP0555839
|
2-[4-[2-[[5-chloro-4-[2-(1-methylimidazol-2-yl)anilino]pyrimidin-2-yl]amino]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-6-yl]piperazin-1-yl]ethanol
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|
C32H39ClN8O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
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CP0842621
|
(1S,2S,3R,4R)-3-[6-Chloro-2-(2-methoxy-4-morpholin-4-ylmethyl-phenyl)-3Himidazo[4,5-b]pyridin-7-ylamino]-bicyclo[2.2.1]hept-5-ene-2-carboxylicacidamide
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|
C26H29ClN6O3
|
1
|
| 1 |
IC50 = 60 nM
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CP0226176
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2-[4-[2-[[5-chloro-4-[2-(1,1-dioxo-1,2-thiazolidin-2-yl)anilino]pyrimidin-2-yl]amino]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-6-yl]piperazin-1-yl]ethanol
Show/Hide
|
C31H40ClN7O4S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
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CP0285873
|
6-chloro-17-(4-methylpiperazin-1-yl)-10-propan-2-ylsulfonyl-2,4,8,22-tetrazatetracyclo[14.3.1.13,7.19,13]docosa-1(20),3,5,7(22),9,11,13(21),16,18-nonaene
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|
C26H31ClN6O2S
|
1
|
| 1 |
IC50 = 70 nM
|
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CP0170188
|
5-chloro-4-N-(2-methoxyphenyl)-2-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrimidine-2,4-diamine
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|
C22H25ClN6O
|
1
|
| 1 |
IC50 = 100 nM
|
|
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CP0103868
|
N-[6-chloro-19-methoxy-17-(4-methylpiperazin-1-yl)-2,4,8,22-tetrazatetracyclo[14.3.1.13,7.19,13]docosa-1(19),2,5,7,9,11,13(21),14,16(20),17-decaen-10-yl]-N-methylmethanesulfonamide
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|
C26H30ClN7O3S
|
1
|
| 1 |
IC50 = 120 nM
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|
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CP0110195
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N-[6-chloro-17-(4-methylpiperazin-1-yl)-2,4,8,22-tetrazatetracyclo[14.3.1.13,7.19,13]docosa-1(20),3,5,7(22),9,11,13(21),16,18-nonaen-10-yl]-N-methylmethanesulfonamide
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|
C25H30ClN7O2S
|
1
|
| 1 |
IC50 = 120 nM
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CP0103867
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6-chloro-10-methoxy-17-(4-methylpiperazin-1-yl)-2,4,8,22-tetrazatetracyclo[14.3.1.13,7.19,13]docosa-1(20),3,5,7(22),9,11,13(21),16,18-nonaene
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C24H27ClN6O
|
1
|
| 1 |
IC50 = 150 nM
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CP0275596
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5-chloro-N2-(8-methoxy-3-(2-methoxyethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-N4-(2-methoxy-4-morpholinophenyl)pyrimidine-2,4-diamine
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|
C29H37ClN6O4
|
1
|
| 1 |
IC50 = 150 nM
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CP0704531
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(1S,2S,3R,4R)-3-[6-Chloro-2-(2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridine-7-ylamino]-bicyclo[2.2.1]hept-5-ene-2-carboxylicacidamide
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|
C21H20ClN5O2
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1
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| 1 |
IC50 = 200 nM
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CP0530939
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(1S,2S,3R,4R)-3-[[5-chloro-2-[[(6S)-1-methoxy-6-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
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|
C29H38ClN7O2
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1
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| 1 |
IC50 = 200 nM
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CP0530940
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(1S,2S,3R,4R)-3-[[5-chloro-2-[[(6R)-1-methoxy-6-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
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|
C29H38ClN7O2
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1
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| 1 |
IC50 = 200 nM
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CP0078539
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6-chloro-19-methoxy-17-(4-methylpiperazin-1-yl)-2,4,8,22-tetrazatetracyclo[14.3.1.13,7.19,13]docosa-1(19),3,5,7(22),9,11,13(21),16(20),17-nonaene
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C24H27ClN6O
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1
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| 1 |
IC50 = 800 nM
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CP0283340
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6-chloro-N-methyl-17-(4-methylpiperazin-1-yl)-2,4,8,22-tetrazatetracyclo[14.3.1.13,7.19,13]docosa-1(20),3,5,7(22),9,11,13(21),16,18-nonaene-10-carboxamide
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C25H28ClN7O
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1
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| 1 |
IC50 = 1200 nM
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