| Compound ID |
Compound Name |
Compound Formula |
|
CP0484359
|
(S)-1-(2-(4-(6-cyanonaphthalen-1-yl)piperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide
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|
C27H28N4O2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0434306
|
(S)-1-(2-((S)-4-(6-cyanonaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide
Show/Hide
|
C28H30N4O2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0414812
|
1-[2-(4-Naphthalen-1-yl-piperidin-1-yl)-ethyl]-isochroman-6-carboxylic acid amide
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|
C27H30N2O2
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0910646
|
(1R)-1-(2-((S)-4-(6-cyanonaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-1,3,7,7a-tetrahydroisobenzofuran-5-carboxamide
Show/Hide
|
C27H28N4O2
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0444835
|
(R)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide
Show/Hide
|
C27H30FN3O2
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0496522
|
1-{2-[3-(6-Fluoro-1H-indol-3-yl)-pyrrolidin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
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|
C24H26FN3O2
|
1
|
| 1 |
Ki = 96 nM
|
|
|
|
CP0484374
|
(S)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide
Show/Hide
|
C27H30FN3O2
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0897706
|
(1S)-1-(2-((S)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-1,3,7,7a-tetrahydroisobenzofuran-5-carboxamide
Show/Hide
|
C26H28FN3O2
|
1
|
| 1 |
Ki = 114 nM
|
|
|
|
CP0429491
|
1-{2-[4-(6-Fluoro-1H-indol-3-yl)-piperidin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C25H28FN3O2
|
1
|
| 1 |
Ki = 131 nM
|
|
|
|
CP0382352
|
1-[2-(4-Naphthalen-1-yl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-isochroman-6-carboxylic acid amide
Show/Hide
|
C27H28N2O2
|
1
|
| 1 |
Ki = 153 nM
|
|
|
|
CP0371723
|
1-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C24H24FN3O3
|
1
|
| 1 |
Ki = 155 nM
|
|
|
|
CP0382349
|
1-{2-[4-(6-Fluoro-benzofuran-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C25H25FN2O3
|
1
|
| 1 |
Ki = 155 nM
|
|
|
|
CP0377764
|
1-{2-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C25H25FN2O2S
|
1
|
| 1 |
Ki = 186 nM
|
|
|
|
CP0449623
|
(1R)-1-[2-[4-(7-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3,4-dihydro-1H-isochromene-6-carboxamide
Show/Hide
|
C25H26FN3O2
|
1
|
| 1 |
Ki = 199 nM
|
|
|
|
CP0406435
|
1-{2-[4-(6-Fluoro-benzo[d]isothiazol-3-yl)-piperidin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C24H26FN3O2S
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0077951
|
1-(2-(4-(6-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide
Show/Hide
|
C25H26FN3O2
|
2
|
| 1 |
Ki = 203 nM
|
|
|
| 2 |
Ki = 281 nM
|
|
|
|
CP0431122
|
1-{2-[4-(7-Fluoro-naphthalen-1-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C27H27FN2O2
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0493033
|
1-{2-[4-(6-Fluoro-1H-indazol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C24H25FN4O2
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0460217
|
1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide
Show/Hide
|
C27H30FN3O2
|
1
|
| 1 |
Ki = 281 nM
|
|
|
|
CP0378425
|
1-{2-[4-(6-Fluoro-1H-indol-3-yl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C24H27FN4O2
|
1
|
| 1 |
Ki = 310 nM
|
|
|
|
CP0460141
|
1-{2-[4-(5-Methoxy-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
Ki = 316 nM
|
|
|
|
CP0405805
|
(1S)-1-[2-[4-(7-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3,4-dihydro-1H-isochromene-6-carboxamide
Show/Hide
|
C25H26FN3O2
|
1
|
| 1 |
Ki = 387 nM
|
|
|
|
CP0374878
|
1-{2-[4-(6-Fluoro-1-methyl-1H-indazol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C25H27FN4O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0374882
|
1-{2-[4-(6-Fluoro-1-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C26H28FN3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0391779
|
1-{2-[4-(6-Fluoro-naphthalen-2-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C27H27FN2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0397314
|
1-{2-[4-(6,7-Dichloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C25H25Cl2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0453762
|
1-{2-[4-(7-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C25H26FN3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0460685
|
1-{2-[4-(7-Cyano-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C26H26N4O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0460873
|
1-{2-[4-(6-Chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C25H26ClN3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0471466
|
1-{2-[4-(6,7-Difluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C25H25F2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0496521
|
1-{2-[(S)-4-(6-Fluoro-1H-indol-3-yl)-2-methyl-piperidin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C26H30FN3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0496529
|
1-{2-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C25H26FN3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0524051
|
1-{2-[4-(6-Trifluoromethyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Show/Hide
|
C26H26F3N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0485357
|
(S)-1-(2-(4-(6-fluoronaphthalen-2-yl)piperazin-1-yl)ethyl)isochroman-6-carboxamide
Show/Hide
|
C26H28FN3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0485429
|
(S)-1-(2-((S)-4-(6-fluoronaphthalen-2-yl)-2-methylpiperazin-1-yl)ethyl)isochroman-6-carboxamide
Show/Hide
|
C27H30FN3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0876644
|
(1R)-1-(2-((S)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-1,3,7,7a-tetrahydroisobenzofuran-5-carboxamide
Show/Hide
|
C26H28FN3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
