Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(2-(4-(6-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide
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 PubChem ID
CID: 9802187
SID: 14758182
Canonical SMILES
NC(=O)c1ccc2C(CCN3CCC(=CC3)c3c[nH]c4cc(F)ccc34)OCCc2c1
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Compound Formula C25H26FN3O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
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Serotonin receptor
Uniprot ID
P28222
Gene Name
HTR1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000101 L-M(TK-)
 Cell Line Info 
Mus musculus (Mouse)  2
1
Ki = 203 nM
   TI
   LI
   LO
   TS
2
Ki = 281 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 281 nM