Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01202 , 5-hydroxytryptamine receptor 1B
Gene Name HTR1B
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P28222
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT01202
 
Compound ID Compound Name Compound Formula
CP0059919
3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C25H28N6OS
 2
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
2
Ki = 2.5 nM
   TI
   LI
   LO
   TS
CP0046110
7-methyl-3-[2-(4-quinolin-4-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C25H28N6OS
 2
1
IC50 = 85 nM
   TI
   LI
   LO
   TS
2
Ki = 9.7 nM
   TI
   LI
   LO
   TS
CP0196504
[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
   Show/Hide
C13H15F3N2O3S
 1
1
IC50 = 98 nM
   TI
   LI
   LO
   TS
CP0332330
[3-[2-(diethylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
   Show/Hide
C15H19F3N2O3S
 1
1
IC50 = 530 nM
   TI
   LI
   LO
   TS
CP0036796
[3-[2-(dipropylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
   Show/Hide
C17H23F3N2O3S
 1
1
IC50 = 660 nM
   TI
   LI
   LO
   TS
CP0494608
3-[2-(4-isoquinolin-8-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C25H28N6OS
 1
1
Ki = 0.1 nM
   TI
   LI
   LO
   TS
CP0500568
7-methyl-3-[2-(4-quinolin-8-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C25H28N6OS
 1
1
Ki = 0.3 nM
   TI
   LI
   LO
   TS
CP0500569
3-[2-(4-benzo[b]thiophen-7-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C24H27N5OS2
 1
1
Ki = 0.4 nM
   TI
   LI
   LO
   TS
CP0376629
7-methyl-3-[2-(4-naphthalen-1-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C26H29N5OS
 1
1
Ki = 0.5 nM
   TI
   LI
   LO
   TS
CP0486971
3-{2-[4-(2,3-dihydro-benzofuran-7-yl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C24H29N5O2S
 1
1
Ki = 0.5 nM
   TI
   LI
   LO
   TS
CP0552368
3-[2-(4-isoquinolin-1-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C25H28N6OS
 1
1
Ki = 0.5 nM
   TI
   LI
   LO
   TS
CP0562477
3-{2-[4-(3-chloro-2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C23H28ClN5O2S
 1
1
Ki = 0.5 nM
   TI
   LI
   LO
   TS
CP0491903
3-[2-(4-isoquinolin-5-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C25H28N6OS
 1
1
Ki = 0.9 nM
   TI
   LI
   LO
   TS
CP0340926
1-(7-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)naphthalen-1-yl)-4-methylpiperazine
   Show/Hide
C24H23ClN4O2
 1
1
Ki < 1 nM
   TI
   LI
   LO
   TS
CP0371941
7-methyl-3-{2-[4-(2-phenoxy-phenyl)-piperazin-1-yl]-ethyl}-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C28H31N5O2S
 1
1
Ki = 1.1 nM
   TI
   LI
   LO
   TS
CP0508160
3-[2-(4-biphenyl-2-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C28H31N5OS
 1
1
Ki = 1.1 nM
   TI
   LI
   LO
   TS
CP0499997
3-{2-[4-(2-benzyloxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C29H33N5O2S
 1
1
Ki = 1.2 nM
   TI
   LI
   LO
   TS
CP0371945
2-{4-[2-(7-methyl-4-oxo-5,6,7,8-tetrahydro-4H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-3-yl)-ethyl]-piperazin-1-yl}-benzonitrile
   Show/Hide
C23H26N6OS
 1
1
Ki = 1.4 nM
   TI
   LI
   LO
   TS
CP0499998
3-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C23H29N5O2S
 1
1
Ki = 1.4 nM
   TI
   LI
   LO
   TS
CP0508159
7-methyl-3-[2-(4-quinolin-5-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C25H28N6OS
 1
1
Ki = 1.7 nM
   TI
   LI
   LO
   TS
CP0524378
3-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C22H26ClN5OS
 1
1
Ki = 1.7 nM
   TI
   LI
   LO
   TS
CP0391071
3-{2-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C25H33N5O2S
 1
1
Ki = 2.5 nM
   TI
   LI
   LO
   TS
CP0511007
3-{2-[4-(4-chloro-2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C23H28ClN5O2S
 1
1
Ki = 3.3 nM
   TI
   LI
   LO
   TS
CP0508161
7-methyl-3-[2-(4-o-tolyl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C23H29N5OS
 1
1
Ki = 3.5 nM
   TI
   LI
   LO
   TS
CP0436660
3-{2-[4-(3,5-dichloro-2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C23H27Cl2N5O2S
 1
1
Ki = 3.8 nM
   TI
   LI
   LO
   TS
CP0391068
3-{2-[4-(4,5-dichloro-2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3a':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C23H27Cl2N5O2S
 1
1
Ki = 4.9 nM
   TI
   LI
   LO
   TS
CP0382468
3-{2-[4-(2-methoxy-naphthalen-1-yl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C27H31N5O2S
 1
1
Ki = 5.4 nM
   TI
   LI
   LO
   TS
CP0496567
3-(2-{4-[2-(2,2-dimethyl-propoxy)-phenyl]-piperazin-1-yl}-ethyl)-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C27H37N5O2S
 1
1
Ki = 5.4 nM
   TI
   LI
   LO
   TS
CP0524377
3-{2-[4-(2-methoxy-5-methyl-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C24H31N5O2S
 1
1
Ki = 11.9 nM
   TI
   LI
   LO
   TS
CP0338890
1-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)-4-isopropylpiperazine
   Show/Hide
C25H29ClN4O2
 1
1
Ki = 31 nM
   TI
   LI
   LO
   TS
CP0382467
7-methyl-3-[2-(4-quinolin-2-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C25H28N6OS
 1
1
Ki = 36.6 nM
   TI
   LI
   LO
   TS
CP0562479
3-{2-[4-(2-methoxy-5-trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C24H28F3N5O2S
 1
1
Ki = 42.3 nM
   TI
   LI
   LO
   TS
CP0436661
3-{2-[4-(2,5-dimethoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C24H31N5O3S
 1
1
Ki = 50.2 nM
   TI
   LI
   LO
   TS
CP0486974
3-{2-[4-(5-chloro-2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C23H28ClN5O2S
 1
1
Ki = 70.3 nM
   TI
   LI
   LO
   TS
CP0121280
7-[2-[2-(3-chlorophenyl)ethylamino]ethyl]quinolin-2-amine
   Show/Hide
C19H20ClN3
 1
1
Ki < 100 nM
   TI
   LI
   LO
   TS
CP0499995
3-{2-[4-(4-methoxy-biphenyl-3-yl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C29H33N5O2S
 1
1
Ki = 116.4 nM
   TI
   LI
   LO
   TS
CP0391064
7-methyl-3-[2-(4-quinazolin-4-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
   Show/Hide
C24H27N7OS
 1
1
Ki = 319.6 nM
   TI
   LI
   LO
   TS
CP0408019
1-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)-4-(3,4-dimethylcyclopentyl)piperazine
   Show/Hide
C29H35ClN4O2
 1
1
Ki = 414 nM
   TI
   LI
   LO
   TS
CP0335097
benzyl 5-(4-methylpiperazin-1-yl)-1,3-dihydroisoindole-2-carboxylate
   Show/Hide
C21H25N3O2
 1
1
Ki = 1431 nM
   TI
   LI
   LO
   TS
CP0177507
(1-(4-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)piperazin-1-yl)cyclopentyl)methanol
   Show/Hide
C28H33ClN4O3
 1
1
Ki = 1490 nM
   TI
   LI
   LO
   TS
CP0001212
1-(2-methoxyphenyl)-4-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperazine
   Show/Hide
C23H29N5OS
 1
1
Ki = 2032 nM
   TI
   LI
   LO
   TS
CP0389578
benzyl 7-[4-(3-ethoxy-3-oxopropyl)piperazin-1-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylate
   Show/Hide
C26H33N3O4
 1
1
Ki = 2438 nM
   TI
   LI
   LO
   TS
CP0127400
(-)-Pramipexole
   Show/Hide
C10H17N3S
 1
1
Ki = 3508 nM
   TI
   LI
   LO
   TS
CP0064188
4-[4-(6-methylimidazo[1,2-a]pyrazin-5-yl)-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
   Show/Hide
C21H13F3N4O2
 1
1
Ki = 8800 nM
   TI
   LI
   LO
   TS
CP0064183
4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine
   Show/Hide
C21H16N4O2
 1
1
Ki = 9300 nM
   TI
   LI
   LO
   TS
CP0369306
4-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
   Show/Hide
C21H12F3N3O2
 1
1
Ki = 9300 nM
   TI
   LI
   LO
   TS
CP0244206
7-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]thieno[2,3-c]pyridine
   Show/Hide
C21H12F3N3OS
 1
1
Ki = 9900 nM
   TI
   LI
   LO
   TS
CP0635067
2-amino-6-chloro-3,4-dihydroquinazoline hydrochloride
   Show/Hide
C8H9Cl2N3
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0114041
CHEMBL2058429
   Show/Hide
C15H15BrN4O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0146889
CHEMBL2058420
   Show/Hide
C14H13BrN4O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0237316
CHEMBL2058419
   Show/Hide
C14H13BrN4O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0237317
CHEMBL2058415
   Show/Hide
C14H13BrN4O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0848198
(E)-5-((4-bromo-1H-indol-3-yl)methylene)-3-methyl-2-(methylimino)imidazolidin-4-one
   Show/Hide
C14H13BrN4O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0054519
(1R,12R,13S,17R,21S)-12-ethyl-18-propyl-7-(trifluoromethyl)-10,18-diazapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-2(11),3,5,7,9-pentaene
   Show/Hide
C25H31F3N2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0085414
(3aS,6R,6aS,9aR,9bR)-6-benzyl-1-methyl-3,3a,4,6,6a,7,8,9,9a,9b-decahydro-2H-benzo[de]quinolin-5-one
   Show/Hide
C20H27NO
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0110111
[(4S,5S)-5-methyl-2-thiophen-3-yl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C9H11NOS2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0315736
2-[4-(1H-imidazol-5-ylmethyl)-4,5-dihydro-1,3-thiazol-2-yl]phenol
   Show/Hide
C13H13N3OS
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0315738
[(4S,5S)-5-methyl-2-phenyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C11H13NOS
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0315739
[(4S,5S)-2-(1H-indol-3-yl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C13H14N2OS
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0315740
[(4S,5S)-5-methyl-2-thiophen-2-yl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C9H11NOS2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0396119
2-[(3aR,6aS)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]thiazol-2-yl]phenol
   Show/Hide
C12H13NOS
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0396120
[(4S,5S)-5-methyl-2-(4-octoxyphenyl)-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C19H29NO2S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0396121
[(4S,5S)-2-(4-butoxyphenyl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C15H21NO2S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0396122
[(4S,5S)-2-(4-hexoxyphenyl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C17H25NO2S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0396185
[(4S,5S)-5-methyl-2-[2-(methylamino)phenyl]-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C12H16N2OS
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0444340
3-[(4S,5S)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]naphthalen-2-ol
   Show/Hide
C15H15NO2S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0475794
[(4S,5S)-2-(furan-2-yl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C9H11NO2S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391901
3-(4-chlorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
   Show/Hide
C13H14ClN3
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391904
3-(4-methylphenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
   Show/Hide
C14H17N3
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391906
3-(4-fluorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
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C13H14FN3
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391907
3-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
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C13H13ClN2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391908
3-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
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C13H13FN2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0456120
3-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
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C14H16N2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0085824
2-[(4S,5R)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]phenol
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C11H13NO2S
 1
1
Ki > 10 nM
   TI
   LI
   LO
   TS
CP0110059
2-[(4S,5S)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]phenol
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C11H13NO2S
 1
1
Ki > 10 nM
   TI
   LI
   LO
   TS
CP0475795
2-[(4R,5R)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]phenol
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C11H13NO2S
 1
1
Ki > 10 nM
   TI
   LI
   LO
   TS
CP0369262
(1-(3-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)propylamino)cyclopentyl)methanol
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C27H32ClN3O3
 1
1
Ki > 300 nM
   TI
   LI
   LO
   TS
CP0341244
(1-(3-(7-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperidin-3-yl)methanol
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C28H34ClN3O3
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS