Compound ID |
Compound Name |
Compound Formula |
CP0059919
|
3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H28N6OS
|
2
|
1 |
IC50 = 35 nM
|
|
|
2 |
Ki = 2.5 nM
|
|
|
CP0046110
|
7-methyl-3-[2-(4-quinolin-4-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H28N6OS
|
2
|
1 |
IC50 = 85 nM
|
|
|
2 |
Ki = 9.7 nM
|
|
|
CP0196504
|
[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
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|
C13H15F3N2O3S
|
1
|
1 |
IC50 = 98 nM
|
|
|
CP0332330
|
[3-[2-(diethylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
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|
C15H19F3N2O3S
|
1
|
1 |
IC50 = 530 nM
|
|
|
CP0036796
|
[3-[2-(dipropylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
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|
C17H23F3N2O3S
|
1
|
1 |
IC50 = 660 nM
|
|
|
CP0494608
|
3-[2-(4-isoquinolin-8-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H28N6OS
|
1
|
1 |
Ki = 0.1 nM
|
|
|
CP0500568
|
7-methyl-3-[2-(4-quinolin-8-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H28N6OS
|
1
|
1 |
Ki = 0.3 nM
|
|
|
CP0500569
|
3-[2-(4-benzo[b]thiophen-7-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C24H27N5OS2
|
1
|
1 |
Ki = 0.4 nM
|
|
|
CP0376629
|
7-methyl-3-[2-(4-naphthalen-1-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C26H29N5OS
|
1
|
1 |
Ki = 0.5 nM
|
|
|
CP0486971
|
3-{2-[4-(2,3-dihydro-benzofuran-7-yl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C24H29N5O2S
|
1
|
1 |
Ki = 0.5 nM
|
|
|
CP0552368
|
3-[2-(4-isoquinolin-1-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H28N6OS
|
1
|
1 |
Ki = 0.5 nM
|
|
|
CP0562477
|
3-{2-[4-(3-chloro-2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C23H28ClN5O2S
|
1
|
1 |
Ki = 0.5 nM
|
|
|
CP0491903
|
3-[2-(4-isoquinolin-5-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H28N6OS
|
1
|
1 |
Ki = 0.9 nM
|
|
|
CP0340926
|
1-(7-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)naphthalen-1-yl)-4-methylpiperazine
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|
C24H23ClN4O2
|
1
|
1 |
Ki < 1 nM
|
|
|
CP0371941
|
7-methyl-3-{2-[4-(2-phenoxy-phenyl)-piperazin-1-yl]-ethyl}-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C28H31N5O2S
|
1
|
1 |
Ki = 1.1 nM
|
|
|
CP0508160
|
3-[2-(4-biphenyl-2-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C28H31N5OS
|
1
|
1 |
Ki = 1.1 nM
|
|
|
CP0499997
|
3-{2-[4-(2-benzyloxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C29H33N5O2S
|
1
|
1 |
Ki = 1.2 nM
|
|
|
CP0371945
|
2-{4-[2-(7-methyl-4-oxo-5,6,7,8-tetrahydro-4H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-3-yl)-ethyl]-piperazin-1-yl}-benzonitrile
Show/Hide
|
C23H26N6OS
|
1
|
1 |
Ki = 1.4 nM
|
|
|
CP0499998
|
3-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C23H29N5O2S
|
1
|
1 |
Ki = 1.4 nM
|
|
|
CP0508159
|
7-methyl-3-[2-(4-quinolin-5-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H28N6OS
|
1
|
1 |
Ki = 1.7 nM
|
|
|
CP0524378
|
3-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C22H26ClN5OS
|
1
|
1 |
Ki = 1.7 nM
|
|
|
CP0391071
|
3-{2-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H33N5O2S
|
1
|
1 |
Ki = 2.5 nM
|
|
|
CP0511007
|
3-{2-[4-(4-chloro-2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C23H28ClN5O2S
|
1
|
1 |
Ki = 3.3 nM
|
|
|
CP0508161
|
7-methyl-3-[2-(4-o-tolyl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C23H29N5OS
|
1
|
1 |
Ki = 3.5 nM
|
|
|
CP0436660
|
3-{2-[4-(3,5-dichloro-2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C23H27Cl2N5O2S
|
1
|
1 |
Ki = 3.8 nM
|
|
|
CP0391068
|
3-{2-[4-(4,5-dichloro-2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3a':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C23H27Cl2N5O2S
|
1
|
1 |
Ki = 4.9 nM
|
|
|
CP0382468
|
3-{2-[4-(2-methoxy-naphthalen-1-yl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C27H31N5O2S
|
1
|
1 |
Ki = 5.4 nM
|
|
|
CP0496567
|
3-(2-{4-[2-(2,2-dimethyl-propoxy)-phenyl]-piperazin-1-yl}-ethyl)-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C27H37N5O2S
|
1
|
1 |
Ki = 5.4 nM
|
|
|
CP0524377
|
3-{2-[4-(2-methoxy-5-methyl-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C24H31N5O2S
|
1
|
1 |
Ki = 11.9 nM
|
|
|
CP0338890
|
1-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)-4-isopropylpiperazine
Show/Hide
|
C25H29ClN4O2
|
1
|
1 |
Ki = 31 nM
|
|
|
CP0382467
|
7-methyl-3-[2-(4-quinolin-2-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H28N6OS
|
1
|
1 |
Ki = 36.6 nM
|
|
|
CP0562479
|
3-{2-[4-(2-methoxy-5-trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C24H28F3N5O2S
|
1
|
1 |
Ki = 42.3 nM
|
|
|
CP0436661
|
3-{2-[4-(2,5-dimethoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C24H31N5O3S
|
1
|
1 |
Ki = 50.2 nM
|
|
|
CP0486974
|
3-{2-[4-(5-chloro-2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C23H28ClN5O2S
|
1
|
1 |
Ki = 70.3 nM
|
|
|
CP0121280
|
7-[2-[2-(3-chlorophenyl)ethylamino]ethyl]quinolin-2-amine
Show/Hide
|
C19H20ClN3
|
1
|
1 |
Ki < 100 nM
|
|
|
CP0499995
|
3-{2-[4-(4-methoxy-biphenyl-3-yl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C29H33N5O2S
|
1
|
1 |
Ki = 116.4 nM
|
|
|
CP0391064
|
7-methyl-3-[2-(4-quinazolin-4-yl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C24H27N7OS
|
1
|
1 |
Ki = 319.6 nM
|
|
|
CP0408019
|
1-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)-4-(3,4-dimethylcyclopentyl)piperazine
Show/Hide
|
C29H35ClN4O2
|
1
|
1 |
Ki = 414 nM
|
|
|
CP0335097
|
benzyl 5-(4-methylpiperazin-1-yl)-1,3-dihydroisoindole-2-carboxylate
Show/Hide
|
C21H25N3O2
|
1
|
1 |
Ki = 1431 nM
|
|
|
CP0177507
|
(1-(4-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)piperazin-1-yl)cyclopentyl)methanol
Show/Hide
|
C28H33ClN4O3
|
1
|
1 |
Ki = 1490 nM
|
|
|
CP0001212
|
1-(2-methoxyphenyl)-4-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperazine
Show/Hide
|
C23H29N5OS
|
1
|
1 |
Ki = 2032 nM
|
|
|
CP0389578
|
benzyl 7-[4-(3-ethoxy-3-oxopropyl)piperazin-1-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylate
Show/Hide
|
C26H33N3O4
|
1
|
1 |
Ki = 2438 nM
|
|
|
CP0127400
|
(-)-Pramipexole
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|
C10H17N3S
|
1
|
1 |
Ki = 3508 nM
|
|
|
CP0064188
|
4-[4-(6-methylimidazo[1,2-a]pyrazin-5-yl)-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
Show/Hide
|
C21H13F3N4O2
|
1
|
1 |
Ki = 8800 nM
|
|
|
CP0064183
|
4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine
Show/Hide
|
C21H16N4O2
|
1
|
1 |
Ki = 9300 nM
|
|
|
CP0369306
|
4-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
Show/Hide
|
C21H12F3N3O2
|
1
|
1 |
Ki = 9300 nM
|
|
|
CP0244206
|
7-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]thieno[2,3-c]pyridine
Show/Hide
|
C21H12F3N3OS
|
1
|
1 |
Ki = 9900 nM
|
|
|
CP0635067
|
2-amino-6-chloro-3,4-dihydroquinazoline hydrochloride
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|
C8H9Cl2N3
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0114041
|
CHEMBL2058429
Show/Hide
|
C15H15BrN4O
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0146889
|
CHEMBL2058420
Show/Hide
|
C14H13BrN4O
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0237316
|
CHEMBL2058419
Show/Hide
|
C14H13BrN4O
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0237317
|
CHEMBL2058415
Show/Hide
|
C14H13BrN4O
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0848198
|
(E)-5-((4-bromo-1H-indol-3-yl)methylene)-3-methyl-2-(methylimino)imidazolidin-4-one
Show/Hide
|
C14H13BrN4O
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0054519
|
(1R,12R,13S,17R,21S)-12-ethyl-18-propyl-7-(trifluoromethyl)-10,18-diazapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-2(11),3,5,7,9-pentaene
Show/Hide
|
C25H31F3N2
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0085414
|
(3aS,6R,6aS,9aR,9bR)-6-benzyl-1-methyl-3,3a,4,6,6a,7,8,9,9a,9b-decahydro-2H-benzo[de]quinolin-5-one
Show/Hide
|
C20H27NO
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0110111
|
[(4S,5S)-5-methyl-2-thiophen-3-yl-4,5-dihydro-1,3-thiazol-4-yl]methanol
Show/Hide
|
C9H11NOS2
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0315736
|
2-[4-(1H-imidazol-5-ylmethyl)-4,5-dihydro-1,3-thiazol-2-yl]phenol
Show/Hide
|
C13H13N3OS
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0315738
|
[(4S,5S)-5-methyl-2-phenyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
Show/Hide
|
C11H13NOS
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0315739
|
[(4S,5S)-2-(1H-indol-3-yl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
Show/Hide
|
C13H14N2OS
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0315740
|
[(4S,5S)-5-methyl-2-thiophen-2-yl-4,5-dihydro-1,3-thiazol-4-yl]methanol
Show/Hide
|
C9H11NOS2
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0396119
|
2-[(3aR,6aS)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]thiazol-2-yl]phenol
Show/Hide
|
C12H13NOS
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0396120
|
[(4S,5S)-5-methyl-2-(4-octoxyphenyl)-4,5-dihydro-1,3-thiazol-4-yl]methanol
Show/Hide
|
C19H29NO2S
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0396121
|
[(4S,5S)-2-(4-butoxyphenyl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
Show/Hide
|
C15H21NO2S
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0396122
|
[(4S,5S)-2-(4-hexoxyphenyl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
Show/Hide
|
C17H25NO2S
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0396185
|
[(4S,5S)-5-methyl-2-[2-(methylamino)phenyl]-4,5-dihydro-1,3-thiazol-4-yl]methanol
Show/Hide
|
C12H16N2OS
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0444340
|
3-[(4S,5S)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]naphthalen-2-ol
Show/Hide
|
C15H15NO2S
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0475794
|
[(4S,5S)-2-(furan-2-yl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
Show/Hide
|
C9H11NO2S
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0391901
|
3-(4-chlorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C13H14ClN3
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0391904
|
3-(4-methylphenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C14H17N3
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0391906
|
3-(4-fluorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C13H14FN3
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0391907
|
3-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C13H13ClN2O
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0391908
|
3-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C13H13FN2O
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0456120
|
3-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C14H16N2O
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0085824
|
2-[(4S,5R)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]phenol
Show/Hide
|
C11H13NO2S
|
1
|
1 |
Ki > 10 nM
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CP0110059
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2-[(4S,5S)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]phenol
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C11H13NO2S
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1
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1 |
Ki > 10 nM
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CP0475795
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2-[(4R,5R)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]phenol
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C11H13NO2S
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1
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1 |
Ki > 10 nM
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CP0369262
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(1-(3-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)propylamino)cyclopentyl)methanol
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C27H32ClN3O3
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1
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1 |
Ki > 300 nM
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CP0341244
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(1-(3-(7-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperidin-3-yl)methanol
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C28H34ClN3O3
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1
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1 |
Ki > 1000 nM
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