Brief Information of the Compound and Protein
Compound Name
3-[2-(4-isoquinolin-1-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
    Show/Hide
PubChem ID
CID: 9933975
SID: 14907026
Canonical SMILES
CN1CCc2c(C1)sc1ncn(CCN3CCN(CC3)c3nccc4ccccc34)c(=O)c21
    Show/Hide
Compound Formula C25H28N6OS
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28222
Gene Name
HTR1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 0.5 nM
   TI
   LI
   LO
   TS