| Compound ID |
Compound Name |
Compound Formula |
|
CP0502196
|
(5-(1-cyclobutylpiperidin-4-yloxy)-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C24H30F3N3O3
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0471954
|
(1-(3,4-dichlorophenyl)-5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(4,4-difluoropiperidin-1-yl)methanone
Show/Hide
|
C28H31Cl2F2N3O2
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0471955
|
(5-(1-cyclopropylpiperidin-4-yloxy)-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C23H28F3N3O3
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0453808
|
(5-(1-isopropylpiperidin-4-yloxy)-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C23H30F3N3O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0506037
|
(4,4-difluoropiperidin-1-yl)(5-(1-isopropylpiperidin-4-yloxy)-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl)methanone
Show/Hide
|
C24H30F5N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0271769
|
2-methyl-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5,6,7,8-tetrahydrophthalazin-1-one
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0473620
|
4-[4-[3-(azepan-1-yl)propoxy]phenyl]-2-methylphthalazin-1-one
Show/Hide
|
C24H29N3O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0417486
|
(5-(1-cyclopropylpiperidin-4-yloxy)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C21H27N3O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0453807
|
2-(2-(4,4-difluoropiperidine-1-carbonyl)-5-(1-isopropylpiperidin-4-yloxy)-1H-indol-1-yl)acetonitrile
Show/Hide
|
C24H30F2N4O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0070231
|
3-methyl-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-6,7-dihydro-5H-cyclopenta[d]pyridazin-4-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0399074
|
4-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0078724
|
3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0482220
|
2-methyl-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]isoquinolin-1-one
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0387957
|
(3,3-difluoropiperidin-1-yl)(5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)methanone
Show/Hide
|
C22H29F2N3O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0491081
|
(4,4-Difluoropiperidin-1-yl)[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]methanone
Show/Hide
|
C22H29F2N3O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0194592
|
(R)-4-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofuran-5-yl)benzonitrile
Show/Hide
|
C22H22N2O
|
2
|
| 1 |
Ki = 3 nM
|
|
|
| 2 |
Ki = 31 nM
|
|
|
|
CP0461427
|
1-methyl-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxopyridine-3-carbonitrile
Show/Hide
|
C21H25N3O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0292222
|
6-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-2-methylpyridazin-3-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0387781
|
2-methyl-4-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]phthalazin-1-one
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0447758
|
(4-fluorophenyl) 4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazine-1-carboxylate
Show/Hide
|
C27H34FN3O4
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0490291
|
2-methyl-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]phthalazin-1-one
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0417499
|
(4,4-difluoropiperidin-1-yl)(5-(1-isopropylpiperidin-4-yloxy)-1-(methylsulfonyl)-1H-indol-2-yl)methanone
Show/Hide
|
C23H31F2N3O4S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0417992
|
(4,4-difluoropiperidin-1-yl)(1-(4-fluorophenylsulfonyl)-5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)methanone
Show/Hide
|
C28H32F3N3O4S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0437596
|
(5-(1-tert-butylpiperidin-4-yloxy)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C22H31N3O3
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0496092
|
5-methyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C19H27N3O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0470543
|
2-[4-(1-benzothiophene-2-carbonyl)piperazin-1-yl]-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C29H35N3O3S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0197280
|
3-methyl-1-[4-(3-piperidin-1-ylpropoxy)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyridazin-4-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0077210
|
3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-5,5-dimethyl-1,4-dihydropyridazin-6-one
Show/Hide
|
C21H29N3O2
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0070230
|
2-methyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]-5,6,7,8-tetrahydrophthalazin-1-one
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0072372
|
2-methyl-6-[4-[(2S)-2-methyl-3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0223879
|
3-methyl-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5,6,7,7a-tetrahydro-4aH-cyclopenta[d]pyridazin-4-one
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0246942
|
(4,4-Difluoropiperidin-1-yl)[1-isopropyl-5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl]methanone
Show/Hide
|
C25H35F2N3O2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0387958
|
(4-cyclobutylpiperazin-1-yl)(2-(morpholine-4-carbonyl)-1-(2,2,2-trifluoroethyl)-1H-indol-5-yl)methanone
Show/Hide
|
C24H29F3N4O3
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0453809
|
(1,1-Dioxo-1lambda*6*-thiomorpholin-4-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1-(2,2,2-trifluoro-ethyl)-1H-indol-2-yl]-methanone
Show/Hide
|
C23H30F3N3O4S
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0494446
|
1-(2-(4,4-difluoropiperidine-1-carbonyl)-5-(1-isopropylpiperidin-4-yloxy)-1H-indol-1-yl)ethanone
Show/Hide
|
C24H31F2N3O3
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0435366
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-propan-2-yl-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0473435
|
5-[4-(1-cyclopentylpiperidin-4-yl)oxyphenyl]-3-methyl-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0447757
|
2-[4-(4-fluorobenzoyl)piperazin-1-yl]-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C27H34FN3O3
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
|
CP0210518
|
4-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-methyl-1H-pyridazin-6-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0271597
|
6-[4-(1-cyclopentylpiperidin-4-yl)oxyphenyl]-2-methylpyridazin-3-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0189162
|
1-[4-(1'-cyclobutylspiro[3,4-dihydrochromene-2,4'-piperidine]-6-yl)oxypiperidin-1-yl]-2-methylpropan-1-one
Show/Hide
|
C26H38N2O3
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0525071
|
1'-cyclobutyl-6-piperidin-4-yloxyspiro[3,4-dihydrochromene-2,4'-piperidine]
Show/Hide
|
C22H32N2O2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0282219
|
2-methyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0457185
|
3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-4-methyl-1H-pyridazin-6-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0441107
|
3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 6.7 nM
|
|
|
|
CP0456970
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-(4-fluorophenyl)-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C26H28FN3O2
|
1
|
| 1 |
Ki = 6.7 nM
|
|
|
|
CP0470541
|
phenyl 4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazine-1-carboxylate
Show/Hide
|
C27H35N3O4
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0380706
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-methyl-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0417488
|
(5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C21H29N3O3
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0491039
|
2-(ethoxycarbonyl)-1H-indole-5-carboxylic acid
Show/Hide
|
C12H11NO4
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0505537
|
(1,1-Dioxo-1lambda*6*-thiomorpholin-4-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-methanone
Show/Hide
|
C21H29N3O4S
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0424450
|
5-propan-2-yl-7-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]thieno[2,3-d]pyridazin-4-one
Show/Hide
|
C22H27N3O2S
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0046463
|
3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C18H23N3O2
|
2
|
| 1 |
Ki = 7 nM
|
|
|
| 2 |
Ki = 7.2 nM
|
|
|
|
CP0401216
|
3-[4-(1-cyclopentylpiperidin-4-yl)oxyphenyl]-1H-pyridazin-6-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0398253
|
3-[4-(1-cyclobutylpiperidin-4-yl)oxy-3-fluorophenyl]-5,5-dimethyl-1,4-dihydropyridazin-6-one
Show/Hide
|
C21H28FN3O2
|
1
|
| 1 |
Ki = 7.2 nM
|
|
|
|
CP0055894
|
(1R,6S)-5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 7.3 nM
|
|
|
|
CP0490005
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-propan-2-ylpyridazin-3-one
Show/Hide
|
C21H29N3O2
|
1
|
| 1 |
Ki = 7.6 nM
|
|
|
|
CP0388461
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-phenylpyridazin-3-one
Show/Hide
|
C24H27N3O2
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0271704
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-pyrimidin-2-ylpyridazin-3-one
Show/Hide
|
C22H25N5O2
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0395112
|
1-methyl-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-3-phenylpyridin-2-one
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0437563
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-thiophen-3-ylpyridazin-3-one
Show/Hide
|
C24H27N3O2S
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0441134
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-2,6-dimethylpyridazin-3-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0435364
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-ethyl-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0258253
|
5-[4-(1-cyclopentylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 8.1 nM
|
|
|
|
CP0204973
|
7-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one
Show/Hide
|
C23H29N3O2S
|
1
|
| 1 |
Ki = 8.3 nM
|
|
|
|
CP0123547
|
2-methyl-8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-5,6-dihydrobenzo[h]cinnolin-3-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 8.3 nM
|
|
|
|
CP0486636
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 8.4 nM
|
|
|
|
CP0397274
|
4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C18H23N3O2
|
2
|
| 1 |
Ki = 8.5 nM
|
|
|
| 2 |
Ki = 13 nM
|
|
|
|
CP0167907
|
1-methyl-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C20H26N2O2
|
1
|
| 1 |
Ki = 8.5 nM
|
|
|
|
CP0503415
|
6-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-2-methylpyridazin-3-one
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
Ki = 8.6 nM
|
|
|
|
CP0494534
|
5-methyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 8.7 nM
|
|
|
|
CP0070556
|
3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C18H25N3O2
|
1
|
| 1 |
Ki = 8.8 nM
|
|
|
|
CP0062835
|
2-methyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]phthalazin-1-one
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0391683
|
5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridin-2-one
Show/Hide
|
C19H24N2O2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0077317
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-pyridin-2-ylpyridazin-3-one
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0410375
|
1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethanone
Show/Hide
|
C25H33N3O3S
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0416089
|
1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-[4-(trifluoromethyl)piperidin-1-yl]ethanone
Show/Hide
|
C22H31F3N2O2
|
1
|
| 1 |
Ki = 9.1 nM
|
|
|
|
CP0062831
|
3-methyl-1-[4-(3-piperidin-1-ylpropoxy)phenyl]-5,6,7,7a-tetrahydro-4aH-cyclopenta[d]pyridazin-4-one
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0488287
|
6-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-2-propan-2-ylpyridazin-3-one
Show/Hide
|
C21H28N4O2
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0423908
|
2-[4-(1-methylpyrrole-2-carbonyl)piperazin-1-yl]-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C26H36N4O3
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0466127
|
2-(2-hydroxyethyl)-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C20H27N3O3
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0440670
|
1-(4-fluorophenyl)-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C25H27FN2O2
|
1
|
| 1 |
Ki = 9.6 nM
|
|
|
|
CP0398250
|
(4R)-3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 9.6 nM
|
|
|
|
CP0466128
|
3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-pyridin-2-yl-1H-pyridazin-6-one
Show/Hide
|
C23H26N4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0461426
|
1-benzyl-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0418921
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-(2,2,2-trifluoroethyl)-4,5-dihydropyridazin-3-one
Show/Hide
|
C20H26F3N3O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0399073
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-(6-methylpyridin-2-yl)pyridazin-3-one
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0093208
|
1-[4-(1'-cyclobutylspiro[3,4-dihydrochromene-2,4'-piperidine]-6-yl)oxypiperidin-1-yl]ethanone
Show/Hide
|
C24H34N2O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0459565
|
2-ethyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0456101
|
2-(2-fluoroethyl)-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C20H26FN3O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0494716
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-(2,2,2-trifluoroethyl)pyridazin-3-one
Show/Hide
|
C20H24F3N3O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0428265
|
2-benzyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C25H29N3O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0078015
|
4-methyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0490289
|
7-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-propylthieno[2,3-d]pyridazin-4-one
Show/Hide
|
C23H29N3O2S
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0490290
|
2-[(4-chlorophenyl)methyl]-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]phthalazin-1-one
Show/Hide
|
C29H30ClN3O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0508562
|
5-[(4-chlorophenyl)methyl]-7-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]thieno[2,3-d]pyridazin-4-one
Show/Hide
|
C27H28ClN3O2S
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0387519
|
1-methyl-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C20H26N2O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0392530
|
6-[6-(1-cyclopentylpiperidin-4-yl)oxypyridin-3-yl]-2-methylpyridazin-3-one
Show/Hide
|
C20H26N4O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0525000
|
2-methylpropyl 4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazine-1-carboxylate
Show/Hide
|
C25H39N3O4
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0077302
|
(1S,6R)-5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0491083
|
morpholin-4-yl-[5-[1-(oxetan-3-yl)piperidin-4-yl]oxy-1-(2,2,2-trifluoroethyl)indol-2-yl]methanone
Show/Hide
|
C23H28F3N3O4
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0070554
|
5,5-dimethyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1,4-dihydropyridazin-6-one
Show/Hide
|
C20H29N3O2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0427598
|
4-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-methyl-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0077209
|
(4S)-3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0417489
|
(3-hydroxypyrrolidin-1-yl)(5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)methanone
Show/Hide
|
C21H29N3O3
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0499348
|
6-[3-chloro-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-methylpyridazin-3-one
Show/Hide
|
C19H24ClN3O2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0188655
|
8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-5,6-dihydro-2H-benzo[h]cinnolin-3-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0114141
|
2-(4-benzoylpiperazin-1-yl)-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C27H35N3O3
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0437567
|
6-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-2-pyridin-2-ylpyridazin-3-one
Show/Hide
|
C24H26N4O2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0428469
|
2-methyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4,5-dihydropyridazin-3-one
Show/Hide
|
C19H27N3O2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0461672
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-phenyl-4,5-dihydropyridazin-3-one
Show/Hide
|
C24H29N3O2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0093209
|
[4-(1'-cyclobutylspiro[3,4-dihydrochromene-2,4'-piperidine]-6-yl)oxypiperidin-1-yl]-cyclopropylmethanone
Show/Hide
|
C26H36N2O3
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0399719
|
2-[4-(furan-2-carbonyl)piperazin-1-yl]-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C25H33N3O4
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0437564
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-(3-methylpyridin-2-yl)pyridazin-3-one
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0066511
|
1'-cyclobutyl-6-(1-methylsulfonylpiperidin-4-yl)oxyspiro[3,4-dihydrochromene-2,4'-piperidine]
Show/Hide
|
C23H34N2O4S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0139334
|
8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-2-propan-2-yl-5,6-dihydrobenzo[h]cinnolin-3-one
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0410374
|
2,2,2-trifluoro-1-[4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazin-1-yl]ethanone
Show/Hide
|
C22H30F3N3O3
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0466013
|
3-methyl-5-[4-(1-propan-2-ylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0433181
|
2-benzyl-6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]pyridazin-3-one
Show/Hide
|
C24H27N3O
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0093210
|
1'-cyclobutyl-6-(1-cyclopropylsulfonylpiperidin-4-yl)oxyspiro[3,4-dihydrochromene-2,4'-piperidine]
Show/Hide
|
C25H36N2O4S
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0431300
|
7-[4-(3-piperidin-1-ylpropoxy)phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one
Show/Hide
|
C23H29N3O2S
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0467406
|
5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1-phenylpyridin-2-one
Show/Hide
|
C25H28N2O2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0488288
|
3-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-1H-pyridazin-6-one
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0227894
|
8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-5,6-dihydro-3H-benzo[f]cinnolin-2-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0123612
|
methyl 4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazine-1-carboxylate
Show/Hide
|
C22H33N3O4
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0390401
|
4-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-1H-pyridazin-6-one
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0482218
|
1-methyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C20H26N2O2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0461673
|
3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4-pyridin-2-yl-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0410373
|
2-(3,3-difluoropyrrolidin-1-yl)-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C20H28F2N2O2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0512832
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-pyridin-2-ylpyridazin-3-one
Show/Hide
|
C23H26N4O2
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0473623
|
2-[(4-chlorophenyl)methyl]-4-[4-(3-piperidin-1-ylpropoxy)phenyl]phthalazin-1-one
Show/Hide
|
C29H30ClN3O2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0430677
|
8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-2-phenyl-5,6-dihydrobenzo[h]cinnolin-3-one
Show/Hide
|
C26H29N3O2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0416088
|
ethyl 4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazine-1-carboxylate
Show/Hide
|
C23H35N3O4
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0450683
|
1-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperidine-4-carbonitrile
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0549244
|
1'-cyclobutyl-6-(1-ethylsulfonylpiperidin-4-yl)oxyspiro[3,4-dihydrochromene-2,4'-piperidine]
Show/Hide
|
C24H36N2O4S
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0427350
|
2-benzyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4,5-dihydropyridazin-3-one
Show/Hide
|
C25H31N3O2
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0395345
|
2-(4-chlorophenyl)-6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]pyridazin-3-one
Show/Hide
|
C23H24ClN3O
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0474044
|
8-(1-cyclobutylpiperidin-4-yl)oxy-4,4a,5,6-tetrahydro-2H-benzo[h]cinnolin-3-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0542408
|
1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-(4-methylsulfonylpiperazin-1-yl)ethanone
Show/Hide
|
C21H33N3O4S
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0072371
|
6-[3-fluoro-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-methylpyridazin-3-one
Show/Hide
|
C19H24FN3O2
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0522574
|
1'-cyclobutyl-6-(1-propan-2-ylsulfonylpiperidin-4-yl)oxyspiro[3,4-dihydrochromene-2,4'-piperidine]
Show/Hide
|
C25H38N2O4S
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0372971
|
(5-(1-isopropylpiperidin-4-ylamino)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C21H30N4O2
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0428471
|
4-methyl-3-[4-(3-piperidin-1-ylpropoxy)phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C19H27N3O2
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0398254
|
3-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-5,5-dimethyl-1,4-dihydropyridazin-6-one
Show/Hide
|
C20H28N4O2
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0524999
|
2-(4-acetylpiperazin-1-yl)-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C22H33N3O3
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0380162
|
1-(2,4-difluorophenyl)-3-[4-(3-piperidin-1-ylpropoxy)phenyl]urea
Show/Hide
|
C21H25F2N3O2
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0494438
|
(5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(4-methoxypiperidin-1-yl)methanone
Show/Hide
|
C23H33N3O3
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0508446
|
3-[4-(3-piperidin-1-ylpropoxy)phenyl]-1H-pyridazin-6-one
Show/Hide
|
C18H23N3O2
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0406981
|
1-[4-[2-(diethylamino)ethoxy]phenyl]-3-[4-(2-methylpropoxy)phenyl]thiourea
Show/Hide
|
C23H33N3O2S
|
1
|
| 1 |
Ki = 39.9 nM
|
|
|
|
CP0438280
|
3-[3,5-difluoro-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C18H21F2N3O2
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0410758
|
tert-butyl 4-(1'-cyclobutylspiro[3,4-dihydrochromene-2,4'-piperidine]-6-yl)oxypiperidine-1-carboxylate
Show/Hide
|
C27H40N2O4
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0512531
|
6-[3,5-difluoro-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-methylpyridazin-3-one
Show/Hide
|
C19H23F2N3O2
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0401129
|
6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-2-phenylpyridazin-3-one
Show/Hide
|
C23H25N3O
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0452072
|
3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-pyridin-2-yl-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0499398
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-pyridin-2-yl-4,5-dihydropyridazin-3-one
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
Ki = 42 nM
|
|
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CP0513526
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3-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-1H-pyridazin-6-one
Show/Hide
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C17H21N3O
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1
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| 1 |
Ki = 43 nM
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CP0134393
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2-(4,4-difluoropiperidin-1-yl)-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
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C21H30F2N2O2
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1
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| 1 |
Ki = 43 nM
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CP0494483
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3-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-1H-pyridazin-6-one
Show/Hide
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C17H21N3O2
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1
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| 1 |
Ki = 45 nM
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CP0398252
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2-methyl-6-[4-(1-propan-2-ylpiperidin-4-yl)oxyphenyl]pyridazin-3-one
Show/Hide
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C19H25N3O2
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1
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| 1 |
Ki = 46 nM
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CP0455351
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6-[4-[3-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]propoxy]phenyl]-2-methylpyridazin-3-one
Show/Hide
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C19H25N3O3
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1
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| 1 |
Ki = 48 nM
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CP0091564
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2-(4-fluorophenyl)-6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]pyridazin-3-one
Show/Hide
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C23H24FN3O
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1
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| 1 |
Ki = 48 nM
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CP0432893
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2-(3,3-difluoropiperidin-1-yl)-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
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C21H30F2N2O2
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1
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| 1 |
Ki = 48 nM
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CP0499237
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3-[4-[3-[(2S)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
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C18H23N3O2
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1
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| 1 |
Ki = 50 nM
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CP0066136
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1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-morpholin-4-ylethanone
Show/Hide
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C20H30N2O3
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1
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| 1 |
Ki = 50 nM
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CP0428567
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3-[6-(1-cyclopentylpiperidin-4-yl)oxypyridin-3-yl]-1H-pyridazin-6-one
Show/Hide
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C19H24N4O2
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1
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| 1 |
Ki = 51 nM
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CP0159228
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5-[4-(1-propan-2-ylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
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C19H25N3O2
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1
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| 1 |
Ki = 51 nM
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CP0528020
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2-methyl-6-[4-[(2R)-2-methyl-3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
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C20H27N3O2
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1
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| 1 |
Ki = 52 nM
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CP0496514
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azepan-1-yl-[5-(1-propan-2-ylpiperidin-4-yl)oxy-1H-indol-2-yl]methanone
Show/Hide
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C23H33N3O2
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1
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| 1 |
Ki = 53 nM
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CP0517470
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8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-4,4a,5,6-tetrahydro-2H-benzo[h]cinnolin-3-one
Show/Hide
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C20H27N3O2
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1
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| 1 |
Ki = 53 nM
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CP0473624
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7-[4-[3-(4-methylpiperidin-1-yl)propoxy]phenyl]-5-propylthieno[2,3-d]pyridazin-4-one
Show/Hide
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C24H31N3O2S
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1
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| 1 |
Ki = 58 nM
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CP0105108
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2-methyl-6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]pyridazin-3-one
Show/Hide
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C18H23N3O
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1
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| 1 |
Ki = 58 nM
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CP0385548
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4,4-dimethyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1,5-dihydropyridazin-6-one
Show/Hide
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C20H29N3O2
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1
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| 1 |
Ki = 59 nM
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CP0392979
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6-[4-(3-piperidin-1-ylpropoxy)phenyl]-2-(2,2,2-trifluoroethyl)-4,5-dihydropyridazin-3-one
Show/Hide
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C20H26F3N3O2
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1
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| 1 |
Ki = 62 nM
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CP0428470
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6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-propan-2-yl-4,5-dihydropyridazin-3-one
Show/Hide
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C21H31N3O2
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1
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| 1 |
Ki = 63 nM
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CP0503180
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3-[2-fluoro-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
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C18H22FN3O2
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1
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| 1 |
Ki = 69 nM
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CP0466129
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3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4-pyridin-2-yl-1H-pyridazin-6-one
Show/Hide
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C23H26N4O2
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1
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| 1 |
Ki = 70 nM
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CP0511569
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3-[6-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]pyridin-3-yl]-1H-pyridazin-6-one
Show/Hide
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C17H22N4O2
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1
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| 1 |
Ki = 70 nM
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CP0398256
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6-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-2-pyridin-2-ylpyridazin-3-one
Show/Hide
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C23H25N5O2
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1
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| 1 |
Ki = 82 nM
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CP0392980
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4-methyl-3-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
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C18H25N3O2
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1
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| 1 |
Ki = 85 nM
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CP0453817
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morpholin-4-yl-[5-(3-piperidin-1-ylpropoxy)-1H-indol-2-yl]methanone
Show/Hide
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C21H29N3O3
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1
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| 1 |
Ki = 91 nM
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CP0417498
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(6-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
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C21H29N3O3
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1
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| 1 |
Ki = 95 nM
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CP0398255
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3-[6-(1-propan-2-ylpiperidin-4-yl)oxypyridin-3-yl]-1H-pyridazin-6-one
Show/Hide
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C17H22N4O2
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1
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| 1 |
Ki = 101 nM
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CP0494485
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2-methyl-6-[4-(3-piperidin-1-ylpropoxy)phenyl]pyridazin-3-one
Show/Hide
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C19H25N3O2
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1
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| 1 |
Ki = 106 nM
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CP0528021
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2-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-5-(6-oxo-1H-pyridazin-3-yl)benzonitrile
Show/Hide
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C19H22N4O2
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1
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| 1 |
Ki = 111 nM
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CP0499397
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3-[4-[3-[(2S)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
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C18H25N3O2
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1
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| 1 |
Ki = 114 nM
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CP0456238
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2-methyl-6-[4-(2-pyrrolidin-1-ylethyl)phenyl]pyridazin-3-one
Show/Hide
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C17H21N3O
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1
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| 1 |
Ki = 135 nM
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CP0380117
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1-(3,5-dichloro-4-methylphenyl)-3-[4-(3-piperidin-1-ylpropoxy)phenyl]urea
Show/Hide
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C22H27Cl2N3O2
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1
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| 1 |
Ki = 135 nM
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CP0474217
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2-benzyl-8-(3-piperidin-1-ylpropoxy)-5,6-dihydrobenzo[h]cinnolin-3-one
Show/Hide
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C27H31N3O2
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1
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| 1 |
Ki = 140 nM
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CP0396888
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5-[(4-chlorophenyl)methyl]-7-[4-(3-piperidin-1-ylpropoxy)phenyl]thieno[2,3-d]pyridazin-4-one
Show/Hide
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C27H28ClN3O2S
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1
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| 1 |
Ki = 143 nM
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CP0499688
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1-methyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
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C20H26N2O2
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1
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| 1 |
Ki = 144 nM
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CP0473622
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7-[4-[3-(diethylamino)propoxy]phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one
Show/Hide
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C22H29N3O2S
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1
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| 1 |
Ki = 167 nM
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CP0501124
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5-[4-(1-ethylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
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C18H23N3O2
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1
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| 1 |
Ki = 228 nM
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CP0458348
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3-[2-methoxy-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
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C19H25N3O3
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1
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| 1 |
Ki = 229 nM
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CP0476369
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6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-2-pyridin-2-ylpyridazin-3-one
Show/Hide
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C22H24N4O
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1
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| 1 |
Ki = 242 nM
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CP0392978
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3-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
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C17H23N3O2
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1
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| 1 |
Ki = 256 nM
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CP0388464
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2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
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C18H23N3O2
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1
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| 1 |
Ki = 347 nM
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CP0499193
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6-[4-[3-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]propoxy]phenyl]-2-methylpyridazin-3-one
Show/Hide
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C19H25N3O3
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1
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| 1 |
Ki = 427 nM
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CP0428264
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3-[4-(3-morpholin-4-ylpropoxy)phenyl]-1H-pyridazin-6-one
Show/Hide
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C17H21N3O3
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1
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| 1 |
Ki = 822 nM
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CP0532294
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7-[4-[3-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]propoxy]phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one
Show/Hide
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C24H31N3O3S
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1
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| 1 |
Ki = 1167 nM
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CP0492340
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1-methyl-5-[3-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
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C20H26N2O2
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1
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| 1 |
Ki > 500 nM
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CP0431301
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2-methyl-4-[4-(2-piperidin-1-ylethoxy)phenyl]phthalazin-1-one
Show/Hide
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C22H25N3O2
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1
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| 1 |
Ki > 1000 nM
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CP0428566
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2-methyl-6-(4-piperidin-4-yloxyphenyl)pyridazin-3-one
Show/Hide
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C16H19N3O2
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1
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| 1 |
Ki > 1000 nM
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CP0508015
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7-[4-[3-[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]propoxy]phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one
Show/Hide
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C24H31N3O3S
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1
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| 1 |
Ki > 3000 nM
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CP0417290
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1'-cyclobutylspiro[3,4-dihydrochromene-2,4'-piperidine]-6-ol
Show/Hide
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C17H23NO2
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1
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| 1 |
Ki > 3000 nM
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