Brief Information of the Cell Line and Protein
Cell Line ID: CL000083 , MCF-7
 Cell Line Info 
Synonyms
MCF 7
MCF.7
MCF7
Michigan Cancer Foundation-7
ssMCF-7
ssMCF7
MCF7/WT
MCF7-CTRL
IBMF-7
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0031
Protein ID: PT01170 , DNA topoisomerase 1
 Protein Info 
Gene Name TOP1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P11387
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000083
 Cell Line Info 
 Protein ID: PT01170
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0093295
 Compound Info 
(S)-10-Dimethylaminomethyl-4-ethyl-4,9-dihydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione; hydrochloride
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C23H23N3O5
  1
1
IC50 = 1800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0036977
 Compound Info 
(S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]florene-3,13-dione
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C20H16N2O4
  1
1
IC50 = 2500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0556736
 Compound Info 
6-(4-aminophenyl)-N-(3-imidazol-1-ylpropyl)-3-(1,3,4-oxadiazol-2-yl)quinolin-4-amine
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C23H21N7O
  1
1
IC50 = 2500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0438641
 Compound Info 
6-(4-methoxyphenyl)-N-(3-morpholin-4-ylpropyl)-3-(1,3,4-oxadiazol-2-yl)quinolin-4-amine
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C25H27N5O3
  1
1
IC50 = 2510 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0422192
 Compound Info 
N-(3-imidazol-1-ylpropyl)-6-(4-methoxyphenyl)-3-(1,3,4-oxadiazol-2-yl)quinolin-4-amine
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C24H22N6O2
  1
1
IC50 = 2740 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0509640
 Compound Info 
N-(3-imidazol-1-ylpropyl)-6-(4-methoxy-3-methylphenyl)-3-(1,3,4-oxadiazol-2-yl)quinolin-4-amine
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C25H24N6O2
  1
1
IC50 = 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0474388
 Compound Info 
N-(3-imidazol-1-ylpropyl)-6-(4-methylphenyl)-3-(1,3,4-oxadiazol-2-yl)quinolin-4-amine
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C24H22N6O
  1
1
IC50 = 3750 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0474389
 Compound Info 
N-(3-imidazol-1-ylpropyl)-6-(3-methoxyphenyl)-3-(1,3,4-oxadiazol-2-yl)quinolin-4-amine
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C24H22N6O2
  1
1
IC50 = 4110 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS