| Compound ID |
Compound Name |
Compound Formula |
|
CP0080110
|
[[4-[2-(benzotriazol-1-yl)-3-[4-[difluoro(phosphono)methyl]phenyl]-2-quinolin-2-ylpropyl]phenyl]-difluoromethyl]phosphonic acid
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|
C32H26F4N4O6P2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0152540
|
4-{1-Benzotriazol-1-yl-1-[4-(difluoro-phosphono-methyl)-benzyl]-2-[4-(difluoro-phosphono-methyl)-phenyl]-ethyl}-benzoic acid methyl ester
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|
C31H27F4N3O8P2
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0245304
|
[[4-[2-(1,3-benzothiazol-2-yl)-2-(benzotriazol-1-yl)-3-[4-[difluoro(phosphono)methyl]phenyl]propyl]phenyl]-difluoromethyl]phosphonic acid
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|
C30H24F4N4O6P2S
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0112045
|
({4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluoro(phosphono)methyl]phenyl}-2-(3,4-difluorophenyl)propyl]phenyl}difluoromethyl)phosphonic acid
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|
C29H23F6N3O6P2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0151508
|
[[4-[(E)-2-(benzotriazol-1-yl)-5-[4-[difluoro(phosphono)methyl]phenyl]-2-phenylpent-4-enyl]phenyl]-difluoromethyl]phosphonic acid
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|
C31H27F4N3O6P2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0321165
|
({4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluoro(phosphono)methyl]phenyl}-2-phenylpropyl]phenyl}difluoromethyl)phosphonic acid
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|
C29H25F4N3O6P2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0267727
|
[[4-[2-(benzotriazol-1-yl)-3-[3-bromo-4-[difluoro(phosphono)methyl]phenyl]-2-phenylpropyl]phenyl]-difluoromethyl]phosphonic acid
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|
C29H24BrF4N3O6P2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0078105
|
({4-[2-Benzotriazol-1-yl-3-[4-(difluoro-phosphono-methyl)-phenyl]-2-(4-phenyl-thiazol-2-yl)-propyl]-phenyl}-difluoro-methyl)-phosphonic acid
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|
C32H26F4N4O6P2S
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0194946
|
6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluoro(phosphono)methyl]phenyl}-2-phenylpropyl]phenyl}-2-methylquinoline-8-phosphonic acid
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|
C38H32F2N4O6P2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0166681
|
3-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluoro(phosphono)methyl]phenyl}-2-phenylpropyl]phenyl}benzene-1-phosphonic acid
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|
C34H29F2N3O6P2
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0267643
|
[[4-[2-(benzotriazol-1-yl)-2-phenyl-1-[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]ethyl]phenyl]-difluoromethyl]phosphonic acid
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|
C34H26F2N7O3P
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0302509
|
({4-[(4E)-2-(1H-1,2,3-benzotriazol-1-yl)-2,5-diphenylpent-4-en-1-yl]phenyl}difluoromethyl)phosphonic acid
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|
C30H26F2N3O3P
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0081269
|
2,2-Bis-[4-(difluoro-phosphono-methyl)-benzyl]-malonic acid dibenzyl ester
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|
C33H30F4O10P2
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0267562
|
[[4-[2-(benzotriazol-1-yl)-2,5-diphenylpentyl]phenyl]-difluoromethyl]phosphonic acid
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|
C30H28F2N3O3P
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0102074
|
({4-[2-Benzotriazol-1-yl-2-phenyl-3-(2'-sulfamoyl-biphenyl-4-yl)-propyl]-phenyl}-difluoro-methyl)-phosphonic acid
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|
C34H29F2N4O5PS
|
1
|
| 1 |
IC50 = 930 nM
|
|
|
|
CP0287450
|
2,2-Bis-[4-(difluoro-phosphono-methyl)-benzyl]-malonic acid benzyl ester methyl ester
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|
C27H26F4O10P2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0424766
|
[difluoro-[4-(2-oxo-1,2-diphenylethyl)phenyl]methyl]phosphonic acid
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|
C21H17F2O4P
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0212665
|
({4-[2-Benzotriazol-1-yl-3-[4-(difluoro-phosphono-methyl)-phenyl]-2-(1H-tetrazol-5-yl)-propyl]-phenyl}-difluoro-methyl)-phosphonic acid
Show/Hide
|
C24H21F4N7O6P2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0105082
|
(2-bromo-4-(3-oxo-2,3-diphenylpropyl)phenyl)difluoromethylphosphonic acid
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|
C22H18BrF2O4P
|
1
|
| 1 |
IC50 = 1220 nM
|
|
|
|
CP0275477
|
[[4-[3-[4-[difluoro(phosphono)methyl]phenyl]-2,2-bis(phenylmethoxy)propyl]phenyl]-difluoromethyl]phosphonic acid
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|
C31H30F4O8P2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0102048
|
({4-[2-Benzotriazol-1-yl-3-(4-bromo-phenyl)-2-phenyl-propyl]-phenyl}-difluoro-methyl)-phosphonic acid
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|
C28H23BrF2N3O3P
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0303831
|
({4-[2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyl-3-(4-phenylphenyl)propyl]phenyl}difluoromethyl)phosphonic acid
Show/Hide
|
C34H28F2N3O3P
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0245576
|
2,2-Bis-[4-(difluoro-phosphono-methyl)-benzyl]-malonic acid diisopropyl ester
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|
C25H30F4O10P2
|
1
|
| 1 |
IC50 = 1650 nM
|
|
|
|
CP0263427
|
2-(4-Acetylsulfamoyl-benzyl)-2-[4-(difluoro-phosphono-methyl)-benzyl]-malonic acid dibenzyl ester
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|
C34H32F2NO10PS
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0211305
|
2-Benzotriazol-1-yl-3-[4-(difluoro-phosphono-methyl)-phenyl]-2-phenyl-propionic acid benzyl ester
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|
C29H24F2N3O5P
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0268538
|
2-[4-(Carboxy-difluoro-methyl)-benzyl]-2-[4-(difluoro-phosphono-methyl)-benzyl]-malonic acid dibenzyl ester
Show/Hide
|
C34H29F4O9P
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0225529
|
[[4-[(E)-2-benzoyl-2,5-diphenylpent-4-enyl]phenyl]-difluoromethyl]phosphonic acid
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|
C31H27F2O4P
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0278748
|
[[2-chloro-4-(3-oxo-2,3-diphenylpropyl)phenyl]-difluoromethyl]phosphonic acid
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|
C22H18ClF2O4P
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0336775
|
2-(4-(benzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanoic acid
Show/Hide
|
C28H23ClF3NO5S
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
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CP0151233
|
2,2-Bis-[4-(difluoro-phosphono-methyl)-benzyl]-malonic acid monomethyl ester
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|
C20H20F4O10P2
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0212664
|
({4-[2-Benzotriazol-1-yl-3-(4-benzyloxy-phenyl)-2-phenyl-propyl]-phenyl}-difluoro-methyl)-phosphonic acid
Show/Hide
|
C35H30F2N3O4P
|
1
|
| 1 |
IC50 = 4070 nM
|
|
|
|
CP0292182
|
4-{2-[4-(Difluoro-phosphono-methyl)-benzyl]-3-oxo-2,3-diphenyl-propyl}-benzoic acid
Show/Hide
|
C30H25F2O6P
|
1
|
| 1 |
IC50 = 6630 nM
|
|
|
|
CP0205894
|
2-[4-(Difluoro-phosphono-methyl)-benzyl]-2-(4-methanesulfonyl-benzyl)-malonic acid dibenzyl ester
Show/Hide
|
C33H31F2O9PS
|
1
|
| 1 |
IC50 = 7200 nM
|
|
|
|
CP0440715
|
2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)-4-phenethoxyphenyl)-3,3,3-trifluoro-2-hydroxypropanoic acid
Show/Hide
|
C29H25ClF3NO5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0384343
|
2-(4-(4-methoxybenzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanoic acid
Show/Hide
|
C29H25ClF3NO6S
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
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CP0436367
|
2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)-4-(pentyloxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanoic acid
Show/Hide
|
C26H27ClF3NO5S
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
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CP0289829
|
[difluoro-[4-(3-oxo-2,3-diphenylpropyl)phenyl]methyl]phosphonic acid
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|
C22H19F2O4P
|
1
|
| 1 |
IC50 = 16000 nM
|
|
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CP0446532
|
2-(4-(4-fluorobenzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanoic acid
Show/Hide
|
C28H22ClF4NO5S
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
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CP0516528
|
2-(1-benzyl-5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoic acid
Show/Hide
|
C30H24ClF3N2O4S
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
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CP0457723
|
2-(5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoic acid
Show/Hide
|
C29H32ClF3N2O5SSi
|
1
|
| 1 |
IC50 = 32000 nM
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|
|
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CP0528034
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2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)-4-(pyridin-4-ylmethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanoic acid
Show/Hide
|
C27H22ClF3N2O5S
|
1
|
| 1 |
IC50 = 36000 nM
|
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CP0516147
|
2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanoic acid
Show/Hide
|
C21H17ClF3NO4S
|
1
|
| 1 |
IC50 = 37000 nM
|
|
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CP0486824
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2-(5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)-1-(methoxymethyl)-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoic acid
Show/Hide
|
C25H22ClF3N2O5S
|
1
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| 1 |
IC50 = 59000 nM
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