Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
 Cell Line Info 
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01154 , Mineralocorticoid receptor
 Protein Info 
Gene Name NR3C2
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P08235
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053
 Cell Line Info 
 Protein ID: PT01154
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0068586
 Compound Info 
(1S,2R,10S,11S,14S,15R,17S)-17-hydroxy-14-(2-hydroxyacetyl)-2-methyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-15-carbaldehyde
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C21H28O5
  1
1
EC50 = 3.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0422544
 Compound Info 
11BETA-HYDROXYPROGESTERONE
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C21H30O3
  1
1
EC50 = 50 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0035175
 Compound Info 
2',15'-dimethyl-5,5'-dioxo-(9'R)-spiro[tetrahydrofuran-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadec-6'-ene]-9-yl ethanethioate
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C24H32O4S
  1
1
IC50 = 1.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0035186
 Compound Info 
(10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one
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C29H35NO2
  1
1
IC50 = 590 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0845015
 Compound Info 
Asoprinsil
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C28H35NO4
  1
1
IC50 = 1600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0404871
 Compound Info 
5-(7-fluoro-3,3-dimethyl-2-oxo-1H-indol-5-yl)-1-methylpyrrole-2-carbonitrile
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C16H14FN3O
  1
1
IC50 = 3700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0373077
 Compound Info 
3-[5-Ethyl-5-(2-furyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl]-5-fluorobenzonitrile
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C22H17FN2O3
  1
1
IC50 > 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0401079
 Compound Info 
3-(5,5-Dimethyl-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl)-5-fluorobenzonitrile
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C18H15FN2O2
  1
1
IC50 > 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0445223
 Compound Info 
3-[5,5-Di(2-furyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl]-5-fluorobenzonitrile
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C24H15FN2O4
  1
1
IC50 > 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS