| Compound ID |
Compound Name |
Compound Formula |
|
CP0117454
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2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)-N-methylbenzamide
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C23H25ClN6O3
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1
|
| 1 |
IC50 = 6.9 nM
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|
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CP0544191
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2-[[5-chloro-2-[4-[4-[5-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]amino]-5-oxopentyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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C41H43ClN10O7
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1
|
| 1 |
IC50 = 13.6 nM
|
|
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CP0567702
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2-[[5-chloro-2-[4-[4-[5-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]-5-oxopentyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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C41H43ClN10O7
|
1
|
| 1 |
IC50 = 14.9 nM
|
|
|
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CP0567704
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2-[[5-chloro-2-[4-[4-[5-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethylamino]-5-oxopentyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C43H48ClN11O7
|
1
|
| 1 |
IC50 = 16.9 nM
|
|
|
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CP0577480
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2-[[5-chloro-2-[4-[4-[5-[[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]amino]-5-oxopentyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C41H45ClN10O6
|
1
|
| 1 |
IC50 = 17.1 nM
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|
|
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CP0544196
|
2-[[5-chloro-2-[4-[4-[3-[3-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethylamino]-3-oxopropoxy]propyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C44H50ClN11O8
|
1
|
| 1 |
IC50 = 18.4 nM
|
|
|
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CP0572441
|
2-[[5-chloro-2-[4-[4-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C44H51ClN10O9
|
1
|
| 1 |
IC50 = 20.2 nM
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|
|
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CP0571975
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2-[[5-chloro-2-[4-[4-[6-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethylamino]-6-oxohexyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C44H50ClN11O7
|
1
|
| 1 |
IC50 = 23.7 nM
|
|
|
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CP0544193
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2-[[5-chloro-2-[4-[4-[6-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]-6-oxohexyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C42H45ClN10O7
|
1
|
| 1 |
IC50 = 27.6 nM
|
|
|
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CP0546979
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2-[[5-chloro-2-[4-[4-[8-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethylamino]-8-oxooctyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C46H54ClN11O7
|
1
|
| 1 |
IC50 = 29.6 nM
|
|
|
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CP0543539
|
2-[[5-chloro-2-[4-[4-[7-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethylamino]-7-oxoheptyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C45H52ClN11O7
|
1
|
| 1 |
IC50 = 31.4 nM
|
|
|
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CP0546978
|
2-[[5-chloro-2-[4-[4-[2-[2-[2-[[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetyl]amino]ethoxy]ethoxy]ethyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C44H50ClN11O9
|
1
|
| 1 |
IC50 = 37.3 nM
|
|
|
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CP0543414
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2-[[5-chloro-2-[4-[4-[7-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]-7-oxoheptyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C43H47ClN10O7
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
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CP0544197
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[8-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]-8-oxooctyl] 4-[4-[[5-chloro-4-[2-(methylcarbamoyl)anilino]pyrimidin-2-yl]amino]-3-methoxyphenyl]piperazine-1-carbodithioate
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C45H49ClN10O7S2
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1
|
| 1 |
IC50 = 49.5 nM
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|
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CP0554524
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2-[[5-chloro-2-[4-[4-[8-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]-8-oxooctyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C44H49ClN10O7
|
1
|
| 1 |
IC50 = 49.8 nM
|
|
|
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CP0544195
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2-[[5-chloro-2-[4-[4-[10-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethylamino]-10-oxodecyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C48H58ClN11O7
|
1
|
| 1 |
IC50 = 52.5 nM
|
|
|
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CP0544047
|
2-[[5-chloro-2-[4-[4-[8-[[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetyl]amino]octyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C46H54ClN11O7
|
1
|
| 1 |
IC50 = 57.1 nM
|
|
|
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CP0544192
|
[10-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]-10-oxodecyl] 4-[4-[[5-chloro-4-[2-(methylcarbamoyl)anilino]pyrimidin-2-yl]amino]-3-methoxyphenyl]piperazine-1-carbodithioate
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|
C47H53ClN10O7S2
|
1
|
| 1 |
IC50 = 69.5 nM
|
|
|
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CP0543415
|
2-[[5-chloro-2-[4-[4-[9-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]-9-oxononyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C45H51ClN10O7
|
1
|
| 1 |
IC50 = 71.8 nM
|
|
|
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CP0544194
|
2-[[5-chloro-2-[4-[4-[10-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]-10-oxodecyl]piperazin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
Show/Hide
|
C46H53ClN10O7
|
1
|
| 1 |
IC50 = 82.7 nM
|
|
|
